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Science
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l.
10
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2
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May
201
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d
o
w
n
a
n
d
s
tatio
n
ar
y
.
De
tecti
n
g
ab
n
o
r
m
a
l c
o
n
d
itio
n
s
i
s
d
ep
en
d
en
t o
n
t
h
e
h
ea
r
t r
ate
(
HR
)
p
ar
am
eter
o
n
l
y
.
So
m
e
o
f
t
h
e
r
elate
d
liter
atu
r
e
co
n
ce
n
tr
ates
o
n
t
h
e
d
ata
ac
q
u
is
i
tio
n
an
d
t
h
e
h
ar
d
w
ar
e
d
esig
n
o
f
th
e
s
y
s
te
m
.
W
h
ile
m
aj
o
r
ity
u
s
es
w
ir
ele
s
s
tr
an
s
m
is
s
io
n
s
u
ch
as
Gen
er
al
P
ac
k
et
R
ad
io
Ser
v
i
ce
(
GP
R
S),
g
lo
b
al
s
y
s
te
m
f
o
r
m
o
b
ile
co
m
m
u
n
ic
atio
n
s
(
G
SM)
,
an
d
I
n
ter
n
et
f
o
r
r
em
o
te
m
o
n
ito
r
in
g
.
T
h
e
p
r
o
p
o
s
ed
d
esig
n
b
y
A
b
o
-
Z
a
h
h
ad
et.
al.
is
ca
p
ab
le
o
f
m
ea
s
u
r
in
g
v
ital
s
i
g
n
s
s
u
c
h
as
h
ea
r
t
-
r
ate,
b
lo
o
d
p
r
ess
u
r
e,
b
lo
o
d
o
x
y
g
en
le
v
el,
an
d
E
C
G
o
f
t
h
e
p
atien
t
a
n
d
s
en
d
in
g
r
esu
lts
u
s
i
n
g
in
ter
n
et
[
4
]
.
B
u
t
f
o
r
ab
n
o
r
m
al
r
ea
d
in
g
s
,
aler
ts
o
r
d
ata
ar
e
s
en
t
th
r
o
u
g
h
GP
R
S
f
o
r
t
h
e
d
o
cto
r
an
d
GSM
f
o
r
t
h
e
p
atie
n
t
’
s
r
elati
v
es
to
m
in
i
m
ize
t
h
e
co
s
t
o
f
s
e
n
d
in
g
d
ata.
T
h
e
au
th
o
r
s
d
id
n
o
t
p
r
o
v
id
e
t
ests
an
d
r
es
u
lts
to
p
r
o
v
e
th
at
th
eir
p
r
o
p
o
s
ed
d
esig
n
i
s
w
o
r
k
in
g
p
r
o
p
er
l
y
.
I
t
is
ev
id
en
t
i
n
th
eir
s
t
u
d
ies
t
h
at
m
aj
o
r
ity
o
f
th
e
tele
m
ed
ici
n
e
u
s
e
s
in
ter
n
et
to
tr
an
s
f
er
d
ata,
b
e
i
t
w
ir
ed
o
r
w
ir
eless
.
T
h
e
s
u
m
m
ar
ized
tab
le
th
e
y
p
r
o
v
id
ed
s
h
o
w
s
th
at
m
aj
o
r
ity
o
f
au
t
h
o
r
s
co
n
ce
n
t
r
ates
o
n
t
h
e
h
ar
d
w
ar
e
d
esig
n
,
s
ig
n
al
ac
q
u
is
it
io
n
,
a
n
d
en
er
g
y
e
f
f
ic
ien
c
y
.
I
t
w
as
n
o
t
clea
r
l
y
s
tated
w
h
et
h
er
t
h
e
tele
m
ed
icin
e
d
ev
ice
s
ar
e
ca
p
ab
le
o
f
g
i
v
i
n
g
d
ia
g
n
o
s
i
s
b
ased
o
n
t
h
e
ac
q
u
ir
ed
d
ata.
A
d
ev
ice
t
h
at
al
s
o
tr
an
s
m
its
d
at
a
u
s
in
g
GSM
w
as
d
ev
elo
p
ed
b
y
P
at
il
et.
al.
T
h
e
d
esig
n
u
s
e
s
a
3
-
lead
E
C
G
d
ev
ice
an
d
s
h
o
w
s
th
e
r
es
u
lt
s
in
L
iq
u
id
C
r
y
s
tal
Dis
p
la
y
(
L
C
D
)
ch
ar
ac
ter
d
is
p
lay
[
5
]
.
T
h
e
p
ap
er
w
r
itte
n
b
y
Stei
n
h
u
b
l
et.
al.
u
s
ed
B
lu
e
to
o
th
o
r
f
r
eq
u
en
c
y
m
o
d
u
latio
n
o
f
u
ltra
s
o
u
n
d
to
tr
an
s
f
er
th
e
E
C
G
m
ea
s
u
r
e
m
e
n
t
d
ir
ec
tly
to
th
e
s
m
ar
tp
h
o
n
e
[
6
]
.
I
t
u
s
es
a
f
in
g
er
-
co
n
ta
ct
o
n
th
e
b
ac
k
o
f
t
h
e
s
m
ar
tp
h
o
n
e
to
ac
ti
v
ate
th
e
r
ea
d
in
g
p
r
o
ce
s
s
a
n
d
th
e
r
es
u
lts
ar
e
tr
an
s
m
it
ted
to
t
h
e
d
o
cto
r
in
p
o
r
tab
le
d
o
cu
m
e
n
t
f
o
r
m
at
(
P
DF
)
f
o
r
m
at.
I
t
ca
n
g
i
v
e
a
d
iag
n
o
s
is
u
n
li
k
e
w
it
h
t
h
e
p
r
ev
io
u
s
liter
at
u
r
e.
Ho
w
e
v
er
,
it
w
o
u
ld
ta
k
e
ti
m
e
f
o
r
th
e
d
o
cto
r
to
s
ee
th
e
r
esu
l
ts
s
in
ce
t
h
e
r
esu
l
ts
w
ill
b
e
co
n
v
er
ted
f
ir
s
t
to
P
DF
f
ile
b
e
f
o
r
e
s
e
n
d
in
g
i
t to
t
h
e
d
o
cto
r
.
Mia
o
et.
al.
’
s
d
ev
ice
u
s
es
B
lu
eto
o
th
to
tr
a
n
s
f
er
d
ata
[
7
]
.
Ho
w
e
v
er
,
Mia
o
et.
al.
d
esig
n
ed
t
h
eir
o
w
n
co
n
te
x
t
-
a
w
ar
e
E
C
G
d
ev
ice
w
h
ich
ca
n
b
e
u
s
ed
w
h
i
le
r
esti
n
g
o
r
m
o
v
i
n
g
.
Ma
j
o
r
co
n
ce
r
n
is
th
e
u
s
e
o
f
s
ec
u
r
e
d
ig
ita
l
(
S
D)
ca
r
d
to
s
to
r
e
d
ata
s
in
ce
it
w
il
l
b
e
v
er
y
l
i
m
ited
b
ased
o
n
th
e
ca
p
ac
it
y
o
f
t
h
e
ca
r
d
.
T
h
e
s
y
s
te
m
d
o
es
n
o
t
p
r
o
v
id
e
a
d
iag
n
o
s
is
o
n
t
h
e
p
ati
en
t
.
I
t
o
n
l
y
s
h
o
w
s
t
h
e
r
ea
d
in
g
s
o
f
t
h
e
d
if
f
er
en
t
p
ar
am
eter
s
.
An
o
th
er
p
ap
er
wr
itten
b
y
I
r
ian
to
et.
al.
u
s
ed
1
2
-
lead
E
C
G,
g
r
ap
h
ical
L
C
D
an
d
co
m
p
u
ter
f
o
r
d
is
p
la
y
o
f
E
C
G,
s
p
ea
k
er
s
to
h
ea
r
th
e
h
ea
r
tb
ea
ts
,
a
n
d
p
r
in
ter
as
an
ad
d
itio
n
al
o
u
tp
u
t.
T
h
e
a
u
th
o
r
s
d
esi
g
n
ed
t
h
e
b
io
am
p
li
f
ier
s
f
o
r
t
h
e
E
C
G
b
u
t
it
w
a
s
n
o
t
clea
r
l
y
s
tated
if
t
h
e
y
w
er
e
ab
le
to
p
r
o
v
id
e
d
ia
g
n
o
s
is
b
ased
o
n
t
h
e
E
C
G
r
ea
d
in
g
s
[
8
]
.
T
h
e
d
esig
n
b
y
R
izal
et.
al.
t
h
at
m
ea
s
u
r
es
v
ital
s
ig
n
s
s
u
c
h
as
b
lo
o
d
p
r
ess
u
r
e,
p
u
ls
e
r
ate,
E
C
G
a
n
d
te
m
p
er
at
u
r
e
is
s
i
m
il
ar
to
th
e
s
tu
d
y
b
ec
au
s
e
t
h
at
d
a
ta
is
tr
a
n
s
f
er
r
ed
w
ir
eless
l
y
(
d
o
cto
r
an
d
n
u
r
s
e)
an
d
h
as
GUI
f
o
r
t
h
e
r
es
u
lt.
B
ased
o
n
t
h
e
s
a
m
p
le
G
UI
,
th
e
d
iag
n
o
s
is
f
o
r
t
h
e
h
ea
r
t
r
ate
a
n
d
t
h
e
te
m
p
er
atu
r
e
ar
e
in
d
icate
d
b
u
t
n
o
t
th
e
d
iag
n
o
s
i
s
f
o
r
th
e
E
C
G
a
n
d
b
lo
o
d
p
r
ess
u
r
e
[
9
]
.
Fro
m
t
h
ese
ex
i
s
ti
n
g
a
n
d
p
r
ev
io
u
s
s
tu
d
ie
s
,
th
e
p
r
o
p
o
n
en
ts
d
ec
id
ed
co
m
b
in
e
t
h
e
u
s
e
o
f
i
n
ter
n
e
t
an
d
p
r
o
v
id
in
g
a
p
o
s
s
ib
le
d
iag
n
o
s
i
s
b
ased
o
n
th
e
E
C
G
r
ea
d
in
g
s
.
B
o
th
t
h
e
d
o
cto
r
an
d
p
atien
t
’
s
r
elat
iv
e
ca
n
s
ee
t
h
e
E
C
G
r
ea
d
in
g
s
a
n
d
d
iag
n
o
s
i
s
.
On
l
y
t
h
e
d
o
cto
r
ca
n
s
ee
all
th
e
p
atie
n
ts
u
n
d
er
h
i
s
c
ar
e
an
d
ad
d
co
m
m
e
n
ts
o
n
th
ei
r
co
n
d
itio
n
s
.
W
ith
I
n
ter
n
et
co
n
n
ec
ted
m
ed
ical
eq
u
ip
m
e
n
t,
t
h
e
d
ev
ice
s
a
r
e
ab
le
to
au
to
m
atica
ll
y
r
ela
y
co
llected
in
f
o
r
m
atio
n
to
h
ea
l
th
ca
r
e
p
r
o
f
ess
io
n
als
m
ak
i
n
g
th
e
eq
u
ip
m
e
n
t
m
o
r
e
ef
f
ec
t
iv
e
b
y
allo
w
i
n
g
r
ea
l
-
ti
m
e
m
o
n
ito
r
i
n
g
o
f
p
atien
t
h
ea
lt
h
.
A
d
ata
is
s
h
o
w
n
in
a
co
m
p
le
t
e
d
etailed
p
ictu
r
e
o
f
p
atien
t
s
t
atu
s
w
h
ic
h
ca
n
t
h
e
n
b
e
r
ev
ie
w
ed
w
h
er
e
v
er
t
h
e
p
h
y
s
ician
m
a
y
b
e.
B
y
ap
p
l
y
i
n
g
r
em
o
te
-
p
atie
n
t
m
o
n
ito
r
in
g
,
h
ea
lt
h
ca
r
e
p
r
o
f
ess
io
n
al
s
ca
n
co
n
ti
n
u
o
u
s
l
y
g
a
th
er
d
at
a
an
d
u
s
e
it
to
h
elp
d
iag
n
o
s
e
t
h
e
p
atien
t
s
o
th
e
y
co
u
ld
r
ec
eiv
e
th
e
b
est
tr
ea
t
m
e
n
t
as
q
u
ick
l
y
as
p
o
s
s
ib
le.
So
m
e
p
r
o
j
ec
ts
also
aim
to
p
r
ev
en
t
o
r
d
elay
th
e
n
ee
d
f
o
r
ex
p
en
s
i
v
e
lo
n
g
-
ter
m
ca
r
e
an
d
r
ed
u
ce
th
e
n
ee
d
f
o
r
u
n
p
lan
n
ed
h
o
s
p
ital
v
is
i
ts
.
An
o
th
er
b
en
e
f
it
o
f
u
s
i
n
g
I
o
T
in
m
ed
ical
tech
n
o
lo
g
y
is
to
lo
w
er
th
e
m
ar
g
i
n
o
f
er
r
o
r
s
[
3
]
.
Deta
iled
ex
p
lan
atio
n
o
n
h
o
w
th
e
I
o
T
:
E
lectr
o
ca
r
d
io
g
r
am
m
o
n
ito
r
in
g
s
y
s
te
m
w
as
d
ev
elo
p
ed
an
d
test
ed
w
il
l
b
e
d
is
cu
s
s
ed
o
n
th
e
s
u
cc
ee
d
i
n
g
s
ec
tio
n
s
.
Sectio
n
2
ex
p
lai
n
s
th
e
m
e
th
o
d
o
lo
g
y
u
s
ed
an
d
h
o
w
t
h
e
E
C
G
m
o
n
ito
r
i
n
g
d
ev
ice
w
o
r
k
s
.
Sectio
n
3
s
h
o
w
s
t
h
e
r
es
u
lts
o
f
t
h
e
test
i
n
g
an
d
its
in
ter
p
r
etatio
n
.
Sectio
n
4
s
h
o
w
s
th
e
co
n
lu
s
io
n
b
ased
o
n
th
e
r
esu
lt
s
.
2.
RE
S
E
ARCH
M
E
T
H
O
D
R
ap
id
A
p
p
licatio
n
De
v
elo
p
m
en
t
(
R
A
D)
[
10
]
b
eg
in
s
with
r
esear
ch
a
n
d
d
ata
g
ath
e
r
in
g
h
er
ein
co
n
d
u
cted
as
t
h
e
r
ev
ie
w
o
f
t
h
e
r
elate
d
liter
atu
r
es
a
n
d
ca
n
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Evaluation Warning : The document was created with Spire.PDF for Python.
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4
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5
P
h
ilip
p
in
es.
RE
F
E
R
E
NC
E
S
[1
]
P
.
Je
v
o
n
a
n
d
B.
Ew
e
n
s,
M
o
n
it
o
ri
n
g
t
h
e
c
riti
c
a
ll
y
il
l
p
a
ti
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n
t
:
Jo
h
n
W
il
e
y
&
S
o
n
s,
2
0
1
2
.
[2
]
C.
M
.
Ja
d
h
a
v
a
n
d
V
.
Ba
irag
i,
"
De
tec
ti
o
n
&
Clas
sif
ica
ti
o
n
o
f
Ca
rd
iac
A
rrh
y
th
m
ia,"
In
ter
n
a
ti
o
n
a
l
J
o
u
r
n
a
l
o
f
In
fo
rm
a
t
ics
a
n
d
C
o
mm
u
n
ic
a
ti
o
n
T
e
c
h
n
o
l
o
g
y
(
IJ
-
ICT
),
v
o
l.
6
,
p
p
.
3
1
-
3
6
,
2
0
1
7
.
[3
]
G
.
Ch
risto
p
h
e
r,
"
In
tern
e
t
o
f
T
h
in
g
s in
He
a
lt
h
c
a
re
:
W
h
a
t’s
Ne
x
t
f
o
r
Io
T
T
e
c
h
n
o
lo
g
y
in
th
e
He
a
lt
h
S
e
c
to
r,
"
e
d
,
2
0
1
6
.
[4
]
M
.
A
b
o
-
Zah
h
a
d
,
S
.
M
.
A
h
m
e
d
,
a
n
d
O.
El
n
a
h
a
s,
"
A
w
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e
m
e
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e
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y
tele
m
e
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e
s
y
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p
a
ti
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ts
m
o
n
it
o
rin
g
a
n
d
d
iag
n
o
sis,"
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ter
n
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ti
o
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l
jo
u
rn
a
l
o
f
tele
me
d
icin
e
a
n
d
a
p
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ica
ti
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n
s,
v
o
l.
2
0
1
4
,
p
.
4
,
2
0
1
4
.
[5
]
M
.
S
.
P
a
ti
l,
M
.
S
.
Ja
g
d
a
le,
M
.
A
.
G
.
A
.
P
.
M
s,
a
n
d
R.
T
a
p
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se
,
"
W
I
REL
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S
ECG
M
ON
IT
ORI
N
G
S
YST
EM
,
"
2
0
1
6
.
[6
]
J.
A
.
Walsh
,
E.
J.
T
o
p
o
l,
a
n
d
S
.
R.
S
tein
h
u
b
l
,
"
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p
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.
[7
]
F
.
M
iao
,
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Ch
e
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g
,
Y.
He
,
Q.
H
e
,
a
n
d
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L
i,
"
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.
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.
[8
]
B.
G
.
Irian
to
,
B.
B
u
d
h
iaji,
a
n
d
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.
S
y
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if
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,
"
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sig
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El
e
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tro
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ra
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a
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e
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se
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tm
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a
M
icro
c
o
n
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r,
"
I
n
d
o
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e
sia
n
J
o
u
rn
a
l
o
f
El
e
c
trica
l
En
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m
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ter
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l.
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p
.
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0
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6
.
Evaluation Warning : The document was created with Spire.PDF for Python.
I
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:
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[9
]
A
.
Riza
l,
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i,
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J
o
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ri,
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n
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.
Ha
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,
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ro
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ter
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0
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.
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A
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k
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.
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u
sli,
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IT
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im),
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ter
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p
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1
]
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.
F
e
n
t,
J.
G
o
sa
i,
a
n
d
M
.
P
u
rv
a
,
"
T
e
a
c
h
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th
e
i
n
terp
re
tatio
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o
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tro
c
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rd
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ra
m
s:
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h
ich
m
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th
o
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is
b
e
st?
,
"
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o
u
rn
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l
o
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p
.
1
9
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0
1
5
.
[1
2
]
P
.
H.
Ch
a
rlt
o
n
,
T
.
Bo
n
n
ici
,
L
.
Tara
ss
e
n
k
o
,
J.
A
las
tru
e
y
,
D.
A
.
Cl
if
to
n
,
R.
Be
a
le
,
e
t
a
l.
,
"
Ex
trac
ti
o
n
o
f
re
sp
irato
ry
sig
n
a
ls
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ro
m
th
e
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tro
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io
g
ra
m
a
n
d
p
h
o
to
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leth
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s
m
o
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m
:
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a
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p
h
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sio
lo
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ica
l
d
e
ter
m
in
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n
ts,"
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y
sio
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l.
3
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3
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.
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r
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f
ield
,
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h
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o
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se
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h
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s f
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r P
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ra
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tes
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p
.
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6
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0
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.
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4
]
M
.
G
.
Kh
a
n
,
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a
p
id
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in
ter
p
re
ta
ti
o
n
:
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p
ri
n
g
e
r
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c
ien
c
e
&
Bu
sin
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d
ia,
2
0
0
8
.
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5
]
J.
F
ro
st.
(
2
0
1
3
).
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h
e
n
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h
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u
ld
I
U
se
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In
ter
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a
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ter
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In
ter
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ls
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le:
h
tt
p
:
//
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l
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it
a
b
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o
m
/b
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g
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n
tu
re
s
-
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ti
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-
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o
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[1
6
]
M
.
W
e
ip
p
e
rt,
M
.
Ku
m
a
r,
S
.
Kre
u
z
fe
ld
,
D.
A
rn
d
t,
A
.
Ri
e
g
e
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a
n
d
R.
S
to
ll
,
"
Co
m
p
a
riso
n
o
f
th
re
e
m
o
b
il
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d
e
v
ice
s
f
o
r
m
e
a
su
rin
g
R
–
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in
terv
a
ls
a
n
d
h
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a
rt
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v
a
riab
il
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:
P
o
lar
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8
1
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u
u
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o
t
6
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d
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n
a
m
b
u
lato
ry
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s
y
ste
m
,
"
Eu
ro
p
e
a
n
jo
u
rn
a
l
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f
a
p
p
l
ied
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h
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l.
1
0
9
,
p
p
.
7
7
9
-
7
8
6
,
2
0
1
0
.
Evaluation Warning : The document was created with Spire.PDF for Python.
I
n
d
o
n
esia
n
J
E
lec
E
n
g
&
C
o
m
p
Sci
I
SS
N:
2502
-
4752
I
o
T:
E
lectro
ca
r
d
io
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(
E
C
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Mo
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S
ystem
(
K
r
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tin
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Jo
yc
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P
.
Ort
iz
)
489
B
I
O
G
RAP
H
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S
O
F
AUTH
O
RS
Kristin
e
Jo
y
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Ortiz rec
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M
a
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Co
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p
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a
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Un
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m
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a
s M
a
p
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stit
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ro
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ter E
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0
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h
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is c
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rre
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tl
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m
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In
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f
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p
u
ter E
n
g
in
e
e
r
s o
f
th
e
P
h
i
li
p
p
in
e
s
(ICp
E
P
).
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r
re
se
a
rc
h
in
tere
st i
n
c
lu
d
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s se
n
so
rs,
m
icro
c
o
n
tro
ll
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rs,
a
n
d
w
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e
ss
n
e
tw
o
rk
.
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h
n
P
e
ter
Da
v
a
lo
s
re
c
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iv
e
d
h
is
Ba
c
h
e
lo
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d
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re
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Co
m
p
u
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En
g
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rin
g
f
ro
m
M
a
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n
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ll
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e
s
Lag
u
n
a
.
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is
p
ro
f
icie
n
t
in
C+
+
,
C#
,
M
A
TL
A
B,
M
u
lt
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e
ril
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g
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L
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HP,
HT
M
L
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a
n
d
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in
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is
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tere
ste
d
w
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h
e
m
b
e
d
d
e
d
p
r
o
g
ra
m
m
in
g
(F
P
GA
b
o
a
rd
,
m
icro
c
o
n
tro
ll
e
rs),
so
f
twa
re
p
ro
g
r
a
m
m
in
g
(M
a
n
a
g
e
m
e
n
t
T
o
o
ls,
S
QL
)
a
n
d
c
o
n
f
ig
u
rin
g
n
e
t
w
o
rk
d
e
v
ice
s (Ci
sc
o
Ro
u
ter an
d
S
w
it
c
h
e
s).
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o
ra
E
u
se
b
io
re
c
e
iv
e
d
h
e
r
Ba
c
h
e
lo
r’s d
e
g
re
e
in
C
o
m
p
u
ter E
n
g
in
e
e
rin
g
f
ro
m
M
a
la
y
a
n
Co
ll
e
g
e
s L
a
g
u
n
a
.
S
h
e
is a
d
e
p
t
a
t
u
sin
g
p
r
o
g
ra
m
m
in
g
lan
g
u
a
g
e
s su
c
h
a
s C+
+
,
C#
,
C,
V
HD
L
,
A
s
se
m
b
l
y
a
n
d
M
A
TL
AB,
a
n
d
so
f
tw
a
r
e
a
p
p
li
c
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ti
o
n
s
su
c
h
a
s HT
M
L
,
F
lo
w
c
o
d
e
,
M
u
lt
isim
a
n
d
M
S
Of
f
ic
e
a
p
p
li
c
a
ti
o
n
.
S
h
e
is also
k
n
o
w
led
g
e
a
b
le ab
o
u
t
Cisc
o
a
rc
h
it
e
c
tu
re
.
He
r
i
n
tere
sts
in
c
lu
d
e
b
o
th
p
h
y
sic
a
l
a
n
d
li
f
e
sc
ie
n
c
e
,
a
s w
e
ll
a
s p
h
il
o
so
p
h
ica
l
st
u
d
i
e
s.
Do
m
in
ic
T
u
c
a
y
r
e
c
e
i
v
e
d
h
is
Ba
c
h
e
lo
r’s
d
e
g
re
e
in
Co
m
p
u
ter
En
g
in
e
e
rin
g
f
ro
m
M
a
la
y
a
n
Co
ll
e
g
e
s
L
a
g
u
n
a
.
H
is
i
n
tere
sts
w
it
h
c
o
m
p
u
ters
a
n
d
w
it
h
th
e
e
v
o
lv
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tec
h
n
o
lo
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s
e
rv
e
a
s
h
is
d
riv
in
g
f
o
rc
e
to
p
u
rsu
e
h
is ch
o
se
n
c
a
re
e
r.
He
h
a
s
f
in
e
sk
il
ls
w
it
h
so
m
e
p
ro
g
ra
m
m
in
g
lan
g
u
a
g
e
s
a
n
d
so
f
tw
a
re
a
p
p
li
c
a
ti
o
n
s li
k
e
C+
+
,
C#
,
HT
M
L
,
P
H
P
,
V
HL
D an
d
F
lo
w
c
o
d
e
.
Evaluation Warning : The document was created with Spire.PDF for Python.