I
n
t
e
r
n
at
ion
al
Jou
r
n
a
l
of
P
u
b
l
ic
Hea
l
t
h
S
c
ience
(
I
JP
HS
)
Vo
l
.
8
,
N
o
.
3
,
S
e
p
t
e
m
b
e
r
2019
,
pp.
307~313
I
S
S
N:
2252
-
8806,
DO
I
:
10
.
11591/i
j
p
h
s
.
v
8
i
3
.
20254
307
J
our
nal
home
page
:
htt
ps
:
//
w
w
w
.
iaes
c
or
e
.
c
om/jour
nals
/i
nde
x
.
php/I
J
P
HS
A
n
asse
ss
m
e
n
t
of
r
is
k
of
i
od
i
n
e
d
e
f
ic
ie
n
c
y
am
on
g p
r
e
gn
an
t
w
om
e
n
i
n
S
ar
aw
ak
, M
al
ay
si
a
L
im
K
u
an
g
K
u
ay
1
,
T
an
B
e
n
g
C
h
i
n
2
,
M
oh
d
S
h
ai
f
u
l
A
z
l
an
K
as
s
im
3
,
Nur
Az
n
a
M
ah
m
u
d
4
,
Ru
h
ay
a
S
all
e
h
5
,
Cheong
S
iew
M
an
6
,
Nor
a
z
i
z
ah
I
b
r
ah
i
m
Won
g
7
,
C
h
an
Yin
g
Yin
g
8
,
T
ah
ir
Ar
i
s
9
1,
3,
4,
5
,
6,
7
,
8,
9
I
n
s
t
i
t
u
t
e
fo
r
Pu
b
l
i
c
H
e
al
t
h
,
Mi
n
i
s
t
r
y
o
f
H
e
a
l
t
h
,
Mal
a
y
s
i
a
2
N
u
t
ri
t
i
o
n
U
n
i
t
,
Sara
w
a
k
St
at
e
H
e
al
t
h
D
e
p
art
m
e
n
t
,
M
i
n
i
s
t
ry
o
f
H
e
al
t
h
,
Mal
a
y
s
i
a
Ar
t
ic
l
e
I
n
f
o
AB
S
T
RA
CT
A
r
ti
c
le
h
is
tor
y
:
R
e
c
e
i
ve
d
J
u
n
4
,
201
9
R
e
vi
s
e
d
J
u
l
2
1
,
201
9
A
c
c
e
pt
e
d
A
ug
22
,
201
9
Pre
v
i
o
u
s
fi
n
d
i
n
g
s
fro
m
a
s
t
at
e
-
w
i
d
e
I
o
d
i
n
e
D
e
f
i
ci
e
n
cy
D
i
s
o
rd
e
rs
(
I
D
D
)
s
t
u
d
y
am
o
n
g
p
reg
n
a
n
t
w
o
men
(P
W
)
i
n
Sara
w
ak
i
n
d
i
c
at
e
d
t
h
at
PW
are
at
ri
s
k
o
f
I
D
D
an
d
fu
rt
h
e
r
s
t
u
d
y
i
s
n
e
ed
e
d
.
T
h
i
s
p
ap
e
r
d
e
s
c
ri
b
e
s
t
h
e
me
t
h
o
d
o
l
o
g
y
u
s
e
d
i
n
co
n
d
u
c
t
i
n
g
t
h
i
s
s
t
u
d
y
o
n
as
s
e
s
s
me
n
t
o
f
ri
s
k
o
f
i
o
d
i
n
e
d
e
f
i
c
i
en
cy
a
m
o
n
g
p
re
g
n
a
n
t
w
o
men
i
n
Sara
w
ak
,
Ma
l
a
y
s
i
a.
T
h
i
rt
y
m
at
e
r
n
al
c
h
i
l
d
h
e
al
t
h
c
ar
e
c
l
i
n
i
c
s
(MCH
Cs
)
w
e
r
e
s
el
ec
t
e
d
u
s
i
n
g
p
ro
b
ab
i
l
i
t
y
p
ro
p
o
rt
i
o
n
al
t
o
p
o
p
u
l
at
i
o
n
s
i
ze
(PPS)
s
am
p
l
i
n
g
t
ech
n
i
q
u
e
.
T
h
e
PW
s
am
p
l
e
s
i
z
e
w
a
s
c
al
cu
l
at
e
d
b
as
e
d
o
n
9
5
%
c
o
n
f
i
d
en
ce
i
n
t
e
rv
a
l
(C
I
),
r
e
l
at
i
v
e
p
rec
i
s
i
o
n
o
f
5
%
,
d
e
s
i
g
n
e
ff
ec
t
o
f
2
,
an
t
i
ci
p
at
e
d
ID
D
p
r
e
v
a
l
e
n
ce
o
f
6
5
.
0
%
an
d
n
o
n
-
r
e
s
p
o
n
s
e
rat
e
o
f
2
0
%
.
T
h
u
s
,
t
h
e
t
o
t
al
s
am
p
l
e
s
i
z
e
r
e
q
u
i
r
ed
w
as
7
5
0
(2
5
re
s
p
o
n
d
en
t
s
p
e
r
s
el
ec
t
ed
MCH
C).
T
h
e
W
H
O
E
x
p
an
d
ed
Pro
g
ra
mme
o
n
Immu
n
i
zat
i
o
n
(E
P
I
)
s
u
rv
ey
s
ap
p
ro
ac
h
w
as
u
s
ed
t
o
ra
n
d
o
m
l
y
s
el
ec
t
t
h
e
fi
rs
t
re
s
p
o
n
d
en
t
an
d
s
u
b
s
e
q
u
e
n
t
re
s
p
o
n
d
en
t
s
w
e
r
e
c
h
o
s
en
u
n
t
i
l
t
h
e
r
e
q
u
i
r
e
d
n
u
m
b
e
r
o
f
PW
w
as
me
t
.
T
h
e
re
q
u
i
r
ed
d
at
a
w
e
r
e
o
b
t
ai
n
ed
t
h
ro
u
g
h
:
fa
ce
-
to
-
face
i
n
t
e
r
v
i
ew
s
(s
o
c
i
o
-
d
emo
g
rap
h
i
c
an
d
fo
o
d
fr
e
q
u
e
n
cy
q
u
e
s
t
i
o
n
n
a
i
r
e
),
c
l
i
n
i
c
a
l
as
s
e
s
s
m
en
t
s
(t
h
y
r
o
i
d
s
i
z
e
,
an
d
h
y
p
e
r/
h
y
p
o
t
h
y
r
o
i
d
i
s
m
)
an
d
b
i
o
c
h
emi
c
al
a
n
al
y
s
i
s
(u
ri
n
e
an
d
b
l
o
o
d
s
e
r
u
m
).
A
t
o
t
al
o
f
6
7
7
PW
re
s
p
o
n
d
e
d
i
n
t
h
e
s
t
u
d
y
w
i
t
h
a
re
s
p
o
n
s
e
rat
e
o
f
9
0
.
2
%
.
Maj
o
ri
t
y
o
f
t
h
e
PW
w
e
r
e
at
s
ec
o
n
d
g
ra
v
i
d
a,
ag
ed
2
5
-
2
9
y
e
ars
o
l
d
an
d
o
f
Ma
l
a
y
e
t
h
n
i
ci
t
y
.
T
h
e
me
t
h
o
d
o
l
o
g
y
u
s
ed
i
n
t
h
i
s
s
t
u
d
y
w
as
b
as
e
d
o
n
i
n
t
e
r
n
at
i
o
n
al
g
u
i
d
el
i
n
e
s
w
h
i
ch
m
a
y
p
ro
v
i
d
e
s
t
at
e
’s
e
s
t
i
m
at
e
s
.
A
l
l
t
h
e
n
ece
s
s
ary
s
t
e
p
s
w
e
r
e
t
ak
en
i
n
t
o
co
n
s
i
d
e
rat
i
o
n
t
o
e
n
s
u
r
e
v
al
i
d
a
n
d
r
el
i
ab
l
e
fi
n
d
i
n
g
s
o
n
c
u
rr
en
t
i
o
d
i
n
e
s
t
at
u
s
am
o
n
g
PW
.
K
e
y
w
o
r
d
s
:
I
o
di
n
e
de
f
i
c
i
e
n
c
y
d
i
s
o
r
de
r
s
I
o
di
z
e
d
s
a
l
t
P
r
e
gn
a
n
t
w
o
m
e
n
S
a
r
a
wa
k
Co
p
yr
i
g
h
t
©
2
0
1
9
In
s
t
i
t
u
t
e
o
f
A
d
va
n
ced
E
n
g
i
n
ee
r
i
n
g
a
n
d
S
ci
e
n
ce
.
A
l
l
r
i
g
h
t
s
r
e
s
er
ved
.
C
or
r
e
s
pon
din
g
A
u
th
or
:
L
i
m
K
ua
n
g
K
ua
y
,
C
e
n
t
r
e
f
o
r
Oc
c
upa
t
i
o
n
a
l
He
a
l
t
h
R
e
s
e
a
r
c
h
,
I
n
s
t
i
t
ut
e
f
o
r
P
ubl
i
c
He
a
l
t
h
,
M
i
ni
s
t
r
y
o
f
He
a
l
t
h
,
B
a
n
da
r
S
e
t
i
a
Al
a
m
,
40170,
S
e
l
a
n
go
r
,
M
a
l
a
y
s
i
a
.
E
-
m
a
il
:
l
im
kua
n
gku
a
y
@g
m
a
i
l
.
c
o
m
1.
I
NT
RODU
C
T
I
ON
I
o
di
n
e
,
a
n
e
s
s
e
n
t
i
a
l
n
ut
r
i
e
n
t
f
o
r
t
hy
r
o
i
d
h
o
r
m
o
n
e
t
hy
r
o
xi
ne
(
T
4)
a
n
d
t
r
i
i
o
do
t
hy
r
o
ni
ne
(
T
3)
pr
o
duc
t
i
o
n
,
i
s
e
s
s
e
n
t
i
a
l
f
o
r
n
o
r
m
a
l
gr
o
wt
h
a
n
d
de
v
e
l
o
p
m
e
n
t
[
1]
.
A
de
qua
t
e
i
o
di
ne
i
n
t
a
ke
i
s
e
s
s
e
n
t
i
a
l
f
o
r
t
h
e
pr
o
duc
t
i
o
n
o
f
t
hy
r
o
i
d
h
o
r
m
o
n
e
s
.
T
h
e
b
o
d
y
o
f
a
he
a
l
t
hy
a
du
l
t
c
o
n
t
a
i
ns
a
b
o
ut
10
-
20
m
g
o
f
i
o
d
i
n
e
whi
c
h
o
n
a
v
e
r
a
ge
70
-
80%
(
8
-
15
m
g
o
f
i
o
d
i
ne
)
i
s
s
t
or
e
d
i
n
t
hy
r
o
i
d
g
l
a
n
d
[
2]
.
T
h
e
r
e
c
o
m
m
e
n
de
d
da
i
ly
i
o
d
i
n
e
i
n
t
a
ke
c
r
i
t
e
r
i
a
f
o
r
pr
e
-
s
c
h
o
o
l
c
hil
dr
e
n
,
a
du
l
t
s
a
n
d
pr
e
g
n
a
n
t
wo
m
e
n
a
r
e
90
ug/da
y
,
150
ug/da
y
a
n
d
25
0
ug/da
y
,
r
e
s
pe
c
t
i
ve
ly
[
3]
.
I
n
s
u
f
f
i
c
i
e
n
t
s
upp
l
y
o
f
i
o
d
i
ne
r
e
s
u
l
t
s
i
n
i
na
de
qu
a
t
e
t
hy
r
o
i
d
h
o
r
m
o
n
e
pr
o
duc
t
i
o
n
w
hi
c
h
m
a
y
h
a
v
e
m
u
l
t
i
p
l
e
e
f
f
e
c
t
s
o
n
h
u
m
a
n
gr
o
w
t
h
a
nd
de
v
e
l
o
p
m
e
n
t
,
c
o
l
l
e
c
t
i
v
e
ly
t
e
r
m
e
d
i
o
d
i
ne
d
e
f
i
c
i
e
n
c
y
d
i
s
o
r
de
r
s
(
I
DD
)
[
4]
.
W
o
r
l
dw
i
de
,
I
DD
i
s
a
m
a
j
o
r
pu
bli
c
h
e
a
l
t
h
pr
o
bl
e
m
whi
c
h
a
f
f
e
c
t
s
h
u
m
a
n
po
pu
l
a
t
i
o
n
f
r
o
m
e
a
r
ly
f
o
e
t
a
l
li
f
e
t
o
a
dul
t
h
o
o
d
[
5]
.
I
DD
c
a
n
a
f
f
e
c
t
a
ny
o
n
e
o
f
a
ny
a
ge
,
w
i
t
h
t
h
e
m
o
s
t
v
u
l
ne
r
a
bl
e
hi
g
h
-
r
i
s
k
gr
o
up
f
o
r
I
DD
i
n
Evaluation Warning : The document was created with Spire.PDF for Python.
I
S
S
N:
2252
-
8806
I
n
t
.
J
.
P
ubl
i
c
He
a
l
t
h
S
c
i
.
Vo
l
.
8
,
N
o
.
3
,
S
e
p
t
2019
:
307
–
313
308
pr
e
gn
a
n
t
wo
m
e
n
(
P
W
)
[
6]
.
I
o
di
n
e
r
e
qu
i
r
e
m
e
n
t
i
s
hi
g
h
dur
i
n
g
pr
e
gn
a
nc
y
,
i
t
m
a
y
i
nc
r
e
a
s
e
by
50%
due
to
phy
s
i
o
l
o
g
i
c
a
l
c
h
a
n
ge
s
a
n
d
i
nc
r
e
a
s
e
d
i
n
m
a
t
e
r
n
a
l
t
hy
r
o
xi
ne
pr
o
duc
t
i
o
n
[
7]
.
S
e
v
e
r
e
a
n
d
l
o
n
g
-
t
e
r
m
i
o
d
i
ne
d
e
f
i
c
i
e
nc
y
i
n
P
W
r
e
s
u
l
t
s
i
n
s
e
r
i
o
us
a
d
v
e
r
s
e
e
f
f
e
c
t
s
s
uc
h
a
s
i
nc
r
e
a
s
i
n
g
r
i
s
k
o
f
s
t
i
ll
b
i
r
t
h
s
,
a
b
o
r
t
i
o
ns
a
n
d
c
o
n
ge
ni
t
a
l
a
bn
o
r
m
a
li
t
i
e
s
[
8]
.
Ho
we
v
e
r
,
t
h
i
s
pr
o
bl
e
m
c
a
n
b
e
c
o
r
r
e
c
t
e
d
by
m
a
s
s
a
pp
l
i
c
a
t
i
o
n
o
f
i
o
d
i
z
e
d
s
a
l
t
[
9]
,
a
l
s
o
kn
o
wn
a
s
u
ni
v
e
r
s
a
l
s
a
l
t
i
o
d
i
z
a
t
i
o
n
(
USI
)
.
S
i
n
c
e
t
h
e
l
a
r
ge
s
t
pa
r
t
of
i
o
d
i
ne
i
n
t
a
ke
i
s
u
s
ua
l
ly
f
r
o
m
h
o
us
e
h
o
l
d
s
a
l
t
[
10]
,
USI
i
s
t
h
e
o
p
t
i
m
a
l
w
a
y
t
o
e
n
s
ur
e
s
u
f
f
i
c
i
e
n
t
i
n
t
a
ke
o
f
i
o
d
in
e
by
a
l
l
i
nd
i
v
i
dua
l
s
[
11]
,
a
n
d
t
h
e
i
n
t
e
r
n
a
t
i
o
n
a
l
e
x
pe
r
i
e
nc
e
h
a
s
c
o
n
vi
nc
i
ng
ly
de
m
o
n
s
t
r
a
t
e
d
t
h
a
t
USI
i
s
th
e
m
o
s
t
r
e
l
i
a
bl
e
,
s
a
f
e
a
n
d
c
o
s
t
-
e
f
f
e
c
t
i
v
e
wa
y
t
o
e
l
im
i
na
t
e
I
DD
[
12]
.
Nor
m
a
l
ly
,
a
n
a
v
e
r
a
ge
d
a
i
ly
s
a
l
t
in
t
a
ke
in
po
pul
a
t
i
o
n
r
a
n
ge
d
b
e
t
we
e
n
5
-
15g/da
y
m
a
y
pr
o
vi
de
a
ppr
o
xi
m
a
t
e
l
y
150
µ
g
o
f
i
o
d
i
ne
/da
y
a
f
t
e
r
t
a
ki
ng
i
n
t
o
a
c
c
o
un
t
t
h
e
l
o
s
e
o
f
i
o
d
i
ne
i
n
i
o
d
i
z
e
d
s
a
l
t
due
to
c
l
im
a
t
i
c
a
n
d
s
t
or
a
ge
f
a
c
t
o
r
s
[
13]
.
I
n
S
a
r
a
wa
k,
I
DD
i
s
c
o
m
m
o
n
i
n
m
o
s
t
o
f
i
t
s
i
n
t
e
r
i
o
r
a
r
e
a
s
due
t
o
t
h
e
pr
e
do
m
i
na
n
t
l
y
m
o
u
n
t
a
i
n
o
us
t
e
r
r
a
i
n
a
n
d
h
e
a
vy
r
a
i
n
.
Ho
we
v
e
r
,
w
i
t
h
r
a
p
i
d
o
n
go
i
n
gs
o
c
i
o
-
e
c
o
n
o
m
i
c
de
v
e
l
o
p
m
e
n
t
o
v
e
r
t
h
e
pa
s
t
20
y
e
a
r
s
a
n
d
t
h
e
e
m
e
r
g
i
n
g
o
f
n
e
w
t
o
wn
s
hi
ps
,
o
ut
s
i
d
e
f
o
o
ds
i
n
c
l
ud
i
ng
s
e
a
f
o
o
d
a
r
e
n
o
w
m
o
r
e
w
i
de
ly
a
v
a
il
a
bl
e
t
o
t
h
e
o
n
c
e
r
e
m
o
t
e
a
n
d
i
na
c
c
e
s
s
i
b
l
e
a
r
e
a
s
[
14
-
1
5]
.
I
n
2008,
a
Na
t
i
o
n
a
l
I
DD
s
ur
v
e
y
c
o
n
du
c
t
e
d
i
n
M
a
l
a
y
s
i
a
r
e
ve
a
l
e
d
t
h
e
m
e
d
i
a
n
ur
i
na
r
y
i
o
d
i
ne
c
o
n
c
e
n
t
r
a
t
i
o
n
(
m
UI
C
)
o
f
s
c
h
o
o
l
c
hil
dr
e
n
i
n
S
a
r
a
wa
k
wa
s
a
t
b
o
r
de
r
l
i
ne
-
a
de
qu
a
t
e
l
e
v
e
l
(
101.
9
µ
g/L
)
,
a
n
d
i
o
d
i
n
e
s
t
a
t
us
a
m
o
n
g
c
hil
dr
e
n
f
r
o
m
r
ur
a
l
a
r
e
a
s
r
e
m
a
i
ns
i
na
de
qua
t
e
(
m
UI
C
,
96.
6
µ
g/L
)
[
16]
.
He
n
c
e
,
w
i
t
hi
n
t
h
e
s
a
m
e
y
e
a
r
,
a
l
e
g
i
s
l
a
t
i
o
n
o
n
USI
wa
s
e
na
c
t
e
d
i
n
S
a
r
a
wa
k
w
hi
c
h
r
e
qu
i
r
e
d
a
l
l
s
a
l
t
f
o
r
h
u
m
a
n
c
o
n
s
u
m
pt
i
o
n
t
o
b
e
i
o
d
i
z
e
d
w
i
t
h
i
o
d
i
ne
c
o
n
t
e
n
t
o
f
20
ppm
t
o
40
ppm
[
17]
.
I
n
2015,
a
s
t
a
t
e
-
wi
d
e
I
DD
s
t
ud
y
a
m
o
n
g
pr
e
g
n
a
n
t
wo
m
e
n
(
P
W
)
i
n
S
a
r
a
wa
k
r
e
ve
a
l
e
d
a
n
i
na
de
qua
t
e
i
o
d
i
ne
s
t
a
t
us
a
m
o
n
g
t
h
e
s
t
ud
y
pa
r
t
i
c
i
pa
n
t
s
de
s
p
i
t
e
t
h
e
i
m
p
l
e
m
e
n
t
a
t
i
o
n
o
f
t
h
e
m
a
n
da
t
or
y
USI
s
i
nc
e
2008.
T
h
e
m
UI
C
o
f
t
he
P
W
i
n
t
hi
s
s
t
ud
y
wa
s
105.
6
µ
g/L
,
i
n
d
i
c
a
t
i
n
g
i
o
d
i
ne
de
f
i
c
i
e
n
c
y
a
n
d
t
h
e
d
i
s
t
r
i
b
ut
i
o
n
o
f
ur
i
n
a
r
y
i
o
d
i
ne
(
UI
)
l
e
v
e
l
s
s
h
o
we
d
t
h
a
t
a
tot
a
l
o
f
330
P
W
(
65.
0%
)
h
a
d
UI
C
<
150
µ
g/L
[
18]
.
T
h
e
pr
e
s
e
n
t
f
i
nd
i
n
g
s
w
hi
c
h
r
e
po
r
t
e
d
t
h
a
t
P
W
r
e
s
i
d
i
ng
i
n
a
r
e
a
s
wh
e
r
e
pe
o
pl
e
ge
ne
r
a
l
ly
h
a
v
e
s
u
f
f
i
c
i
e
n
t
i
o
d
i
n
e
i
n
t
a
ke
m
a
y
s
t
i
ll
e
x
p
e
r
i
e
nc
e
I
DD
we
r
e
i
n
c
o
nc
o
r
da
n
c
e
w
i
t
h
t
h
o
s
e
o
f
o
t
h
e
r
s
t
udi
e
s
[
19
-
22]
.
T
h
us
,
a
c
o
m
pr
e
h
e
n
s
i
ve
s
t
udy
i
s
wa
r
r
a
n
t
e
d
to
pr
ovi
de
S
a
r
a
wa
k
S
t
a
t
e
He
a
l
t
h
De
pa
r
t
m
e
n
t
(
S
S
HD
)
w
i
t
h
m
o
r
e
r
e
l
e
v
a
n
t
i
nf
o
r
m
a
t
i
o
n
o
n
t
h
e
c
ur
r
e
n
t
s
t
a
t
us
o
f
I
DD
a
m
o
n
g
pr
e
g
n
a
n
t
wo
m
e
n
i
n
S
a
r
a
wa
k
a
f
t
e
r
t
e
n
y
e
a
r
s
o
f
m
a
n
da
t
o
r
y
USI
i
m
p
l
e
m
e
n
t
a
t
i
o
n
s
i
nc
e
2008.
T
hi
s
a
r
t
i
c
l
e
a
im
s
t
o
de
s
c
r
i
be
t
h
e
m
e
t
h
o
do
l
o
g
y
us
e
d
i
n
c
o
n
duc
t
i
n
g
t
hi
s
s
t
ud
y
o
n
a
s
s
e
s
s
m
e
n
t
o
f
r
i
s
k
o
f
i
o
d
i
ne
de
f
i
c
i
e
n
c
y
a
m
o
n
g
pr
e
gn
a
n
t
wo
m
e
n
i
n
S
a
r
a
wa
k,
M
a
l
a
y
s
i
a
.
2.
RE
S
E
AR
CH
M
E
T
HO
D
2
.
1.
S
c
op
e
of
t
h
e
s
t
u
d
y
T
h
e
s
t
a
t
e
-
wi
de
a
s
s
e
s
s
m
e
n
t
o
f
r
i
s
k
o
f
i
o
d
i
ne
de
f
i
c
i
e
n
c
y
a
m
o
n
g
pr
e
g
n
a
n
t
w
o
m
e
n
(
P
W
)
i
n
S
a
r
a
wa
k,
M
a
l
a
y
s
i
a
w
a
s
a
c
o
l
l
a
b
o
r
a
t
i
v
e
s
t
ud
y
b
e
t
we
e
n
I
ns
t
i
t
ut
e
f
o
r
P
ubl
i
c
He
a
l
t
h
,
Na
t
i
o
n
a
l
I
ns
t
i
t
u
t
e
s
o
f
He
a
l
t
h
,
M
i
ni
s
t
r
y
o
f
He
a
l
t
h
M
a
l
a
y
s
i
a
a
n
d
t
h
e
S
a
r
a
wa
k
S
t
a
t
e
He
a
l
t
h
De
pa
r
t
m
e
n
t
(
S
S
HD
)
,
M
i
ni
s
t
r
y
o
f
He
a
l
t
h
M
a
l
a
y
s
i
a
.
T
h
e
s
ur
v
e
y
wa
s
t
a
r
ge
t
e
d
to
p
r
e
gn
a
n
t
wo
m
e
n
i
n
t
he
f
i
r
s
t
t
r
i
m
e
s
t
e
r
wh
o
r
e
gi
s
t
e
r
e
d
a
n
d
r
e
c
e
i
ve
d
a
n
t
e
na
t
a
l
c
a
r
e
i
n
go
ve
r
nm
e
n
t
m
a
t
e
r
n
a
l
c
hil
d
h
e
a
l
t
h
c
a
r
e
c
l
i
n
i
c
s
(
M
C
HC
s
)
.
2
.
2
.
S
am
p
l
in
g
f
r
am
e
an
d
s
am
p
l
e
s
i
z
e
T
h
e
s
a
m
p
li
ng
f
r
a
m
e
us
e
d
wa
s
t
h
e
2016
l
i
s
t
o
f
a
l
l
t
h
e
go
v
e
r
nm
e
n
t
M
C
HC
s
i
n
S
a
r
a
w
a
k.
B
a
s
e
d
o
n
t
h
e
f
r
a
m
e
,
t
h
e
r
e
we
r
e
267
M
C
HC
s
i
n
t
h
e
s
t
a
t
e
.
T
h
e
s
a
m
p
li
ng
d
i
d
n
o
t
i
n
c
l
ude
P
W
f
r
o
m
pr
i
va
t
e
ho
s
pi
t
a
l
s
.
T
h
e
s
a
m
p
li
ng
uni
t
s
f
o
r
t
h
e
s
ur
v
e
y
we
r
e
a
ll
t
h
e
M
C
HC
s
i
n
t
h
e
12
d
i
vi
s
i
o
n
s
i
n
S
a
r
a
w
a
k.
A
tot
a
l
o
f
30
M
C
HC
s
we
r
e
c
o
n
s
i
de
r
e
d
s
u
f
f
i
c
i
e
n
t
(
r
e
c
o
m
m
e
n
de
d
m
i
n
im
u
m
n
u
m
be
r
o
f
c
l
us
t
e
r
to
e
n
s
ur
e
a
r
e
l
a
t
i
ve
l
y
v
a
li
d
pr
e
v
a
l
e
nc
e
e
s
t
i
m
a
t
e
)
due
t
o
l
im
i
t
e
d
r
e
s
o
ur
c
e
s
a
n
d
l
o
g
i
s
t
i
c
s
f
e
a
s
i
b
i
li
t
y
[
3]
.
T
h
e
s
e
M
C
H
C
s
we
r
e
s
e
l
e
c
t
e
d
ba
s
e
d
o
n
pr
o
b
a
b
il
i
t
y
pr
o
por
t
i
o
n
a
l
t
o
s
i
z
e
(
P
P
S
)
m
e
t
h
o
d
whic
h
i
nv
o
l
ve
d
4
s
t
e
ps
:
i
.
L
i
s
t
i
n
g
t
h
e
M
C
H
C
s
t
o
b
e
s
a
m
p
l
e
d,
ii
.
W
r
i
t
i
ng
t
h
e
po
pul
a
t
i
o
n
s
i
z
e
(
b
a
s
e
d
o
n
tot
a
l
po
s
t
-
n
a
t
a
l
m
o
t
h
e
r
vi
s
i
t
to
M
C
HC
s
i
n
2016)
.
i
ii
.
C
u
mm
u
l
a
t
i
n
g
t
hi
s
s
i
z
e
m
e
a
s
ur
e
s
,
a
n
d
i
v
.
T
a
k
i
n
g
s
y
s
t
e
m
a
t
i
c
r
a
n
do
m
s
a
m
p
l
e
o
f
t
h
e
r
e
qu
i
r
e
d
s
i
z
e
f
r
o
m
t
h
e
c
u
m
m
u
l
a
t
e
d
li
s
t
[
23]
.
T
h
e
P
W
s
a
m
p
l
e
s
i
z
e
wa
s
c
a
l
c
u
l
a
t
e
d
us
i
ng
a
n
a
ppr
o
pr
i
a
t
e
f
o
r
m
u
l
a
o
n
t
h
e
b
a
s
i
s
o
f
t
h
e
a
bil
i
t
y
t
o
e
s
t
i
m
a
t
e
t
h
e
pr
e
v
a
l
e
n
c
e
o
f
I
DD
w
i
t
h
a
de
qua
t
e
pr
e
c
i
s
i
o
n
,
a
n
d
wa
s
i
n
f
l
a
t
e
d
to
c
a
t
e
r
f
o
r
e
s
t
i
m
a
t
e
d
d
e
s
ign
e
f
f
e
c
t
a
n
d
n
o
n
-
r
e
s
po
n
s
e
[
24
-
25]
.
T
h
e
s
a
m
p
l
e
s
i
z
e
o
f
t
h
e
s
t
ud
y
wa
s
c
a
l
c
u
l
a
t
e
d
b
a
s
e
d
o
n
95%
c
o
nf
i
d
e
n
t
i
a
l
i
n
t
e
r
v
a
l
(
C
I
)
,
r
e
l
a
t
i
v
e
pr
e
c
i
s
i
o
n
o
f
5%
,
de
s
i
g
n
e
f
f
e
c
t
o
f
2
a
n
d
n
o
n
-
r
e
s
po
n
s
e
r
a
t
e
o
f
20%
.
T
h
e
a
n
t
i
c
i
pa
t
e
d
pr
e
va
l
e
n
c
e
o
f
I
DD
f
o
r
t
h
e
S
a
r
a
wa
k
wa
s
65.
0%
,
b
a
s
e
d
o
n
t
h
e
pr
e
v
a
l
e
nc
e
r
e
po
r
t
e
d,
t
h
e
tot
a
l
s
a
m
p
l
e
s
i
z
e
r
e
qu
i
r
e
d
wa
s
737
(
r
o
un
d
up
to
750
)
.
T
h
e
r
e
f
o
r
e
,
t
h
e
s
a
m
p
l
e
s
i
z
e
p
e
r
M
C
HC
w
il
l
be
25
(
750/30=25)
.
T
h
e
s
a
m
p
l
e
s
i
z
e
a
l
s
o
e
x
c
e
e
ds
t
h
e
W
HO
r
e
c
o
m
m
e
n
de
d
s
a
m
p
l
e
s
i
z
e
o
f
300
f
o
r
r
e
l
i
a
bl
e
a
s
s
e
s
s
m
e
n
t
o
f
i
o
d
i
n
e
s
t
a
t
us
o
f
po
pul
a
t
i
o
n
[
26]
.
T
h
e
W
HO
E
x
pa
n
de
d
P
r
o
gr
a
m
me
o
n
I
m
m
u
ni
z
a
t
i
o
n
(
E
P
I
)
s
ur
v
e
y
s
a
ppr
o
a
c
h
w
a
s
us
e
d
t
o
r
a
n
do
m
ly
s
e
l
e
c
t
t
h
e
f
i
r
s
t
r
e
s
po
n
de
n
t
a
n
d
t
h
e
n
,
s
u
b
s
e
que
n
t
r
e
s
po
n
de
n
t
s
we
r
e
c
h
o
s
e
n
u
n
t
i
l
t
h
e
r
e
qu
i
r
e
d
n
u
m
be
r
o
f
P
W
wa
s
m
e
t
[
23
]
.
T
h
e
i
n
c
l
us
i
o
n
c
r
i
t
e
r
i
a
f
o
r
pa
r
t
i
c
i
pa
t
i
o
n
i
n
t
hi
s
s
t
ud
y
i
nc
l
ude
d
P
W
o
f
f
i
r
s
t
tr
i
m
e
s
t
e
r
(
f
i
r
s
t
12
we
e
ks
o
f
ge
s
t
a
t
i
o
n
)
,
a
ge
d
18
y
e
a
r
s
a
n
d
a
bo
v
e
,
a
n
d
we
r
e
a
tt
e
n
d
i
n
g
a
n
t
e
na
t
a
l
c
a
r
e
a
ppo
i
n
t
m
e
nt
s
a
t
t
h
e
30
s
e
l
e
c
t
e
d
M
C
HC
s
b
e
t
we
e
n
15
J
u
l
y
2018
a
n
d
15
Oc
to
b
e
r
2018.
Evaluation Warning : The document was created with Spire.PDF for Python.
I
n
t
.
J
.
P
ubl
i
c
He
a
l
t
h
S
c
i
.
I
S
S
N:
2252
-
8806
A
n
as
s
e
s
s
me
nt
of
r
is
k
of
iodi
ne
de
fi
c
ienc
y
among
p
r
e
gnant
w
o
me
n
in
Sar
a
w
a
k
,
M
alays
ia
(
L
im
K
uang
K
uay
)
309
2
.
3
.
S
t
u
d
y
i
n
s
t
r
u
m
e
n
t
All
r
e
qu
i
r
e
d
da
t
a
we
r
e
o
b
t
a
i
n
e
d
t
h
r
o
ugh
:
i
n
t
e
r
vi
e
w
s
o
n
m
o
t
h
e
r
’
s
s
o
c
i
o
-
de
m
o
gr
a
phi
c
a
n
d
f
o
o
d
f
r
e
qu
e
n
c
y
i
n
t
a
ke
,
t
hy
r
o
i
d
s
i
z
e
e
x
a
mi
na
t
i
o
n
,
hy
pe
r
/hy
po
t
hy
r
o
i
d
i
s
m
a
s
s
e
s
s
m
e
n
t
a
n
d
a
na
l
y
s
i
s
o
f
ur
i
ne
i
o
d
i
n
e
,
bl
o
o
d
s
e
r
u
m
a
n
d
h
o
us
e
h
o
l
d
s
a
l
t
f
r
o
m
t
he
s
t
ud
y
r
e
s
po
n
de
n
t
s
.
T
h
e
f
a
c
e
-
to
-
f
a
c
e
i
n
t
e
r
vi
e
w
o
f
I
D
D
s
ur
v
e
y
que
s
t
i
o
nna
i
r
e
s
too
k
a
ppr
o
x
i
m
a
t
e
ly
30
m
i
nut
e
s
to
c
o
m
p
l
e
t
e
.
2
.
4
.
S
oc
io
-
d
e
m
ogr
ap
h
ic
an
d
f
ood
f
r
e
q
u
e
n
c
y
in
t
ak
e
T
h
e
de
m
o
gr
a
p
hi
c
que
s
t
i
o
nn
a
i
r
e
i
nc
l
ude
d
que
s
t
i
o
n
s
r
e
l
a
t
e
d
to
pe
r
s
o
n
a
l
i
n
f
o
r
m
a
t
i
o
n
s
uc
h
a
s
a
ge
,
ge
n
de
r
a
n
d
e
t
hni
c
i
t
y
.
T
he
c
o
ns
u
m
pt
i
o
n
pa
t
t
e
r
n
s
of
i
o
d
i
ne
-
r
i
c
h
f
o
o
ds
o
v
e
r
t
h
e
pa
s
t
o
n
e
m
o
n
t
h
(
da
i
ly,
we
e
k
ly
a
n
d
m
o
n
t
hly
)
we
r
e
m
e
a
s
ur
e
d
u
s
i
ng
s
e
mi
-
qua
n
t
i
t
a
ti
ve
f
o
o
d
f
r
e
que
n
c
y
qu
e
s
t
i
o
nn
a
i
r
e
(
F
F
Q)
a
do
pt
e
d
f
r
o
m
t
h
e
Na
t
i
o
n
a
l
I
DD
S
ur
v
e
y
2008
[
16]
.
I
t
i
n
c
l
ude
d
11
io
di
n
e
-
r
i
c
h
f
o
o
d
i
t
e
m
s
s
uc
h
a
s
f
i
s
h
a
n
d
f
i
s
h
pr
o
duc
t
s
,
ot
h
e
r
s
e
a
f
o
o
d
a
n
d
s
e
a
we
e
d,
7
go
i
t
r
o
ge
n
-
r
i
c
h
f
o
o
d
i
t
e
m
s
s
u
c
h
a
s
t
ub
e
r
s
a
n
d
c
a
bba
ge
.
A
f
o
o
d
a
l
b
u
m
c
o
n
t
a
i
ni
ng
p
i
c
t
ur
e
s
o
f
c
o
m
m
o
nly
e
a
t
e
n
i
o
d
i
ne
-
r
i
c
h
f
o
o
d
we
r
e
us
e
d
to
h
e
l
p
t
h
e
r
e
s
po
n
de
n
t
s
i
de
n
t
i
f
y
t
h
e
f
o
od
i
t
e
m
s
.
Ho
us
e
h
o
l
d
ut
e
n
s
il
s
s
uc
h
a
s
c
up
a
n
d
s
po
o
n
we
r
e
a
l
s
o
us
e
d
to
h
e
l
p
t
h
e
r
e
s
po
n
de
n
t
s
qua
n
t
i
f
y
t
h
e
a
m
o
u
n
t
o
f
f
o
o
d
t
a
ke
n
.
2
.
5
.
T
h
yr
oid
s
iz
e
E
nl
a
r
ge
m
e
n
t
o
f
t
h
e
t
hy
r
o
i
d
g
l
a
n
d
i
n
P
W
wa
s
a
s
s
e
s
s
e
d
by
t
h
e
t
r
a
i
n
e
d
s
t
a
f
f
n
ur
s
e
s
a
n
d
gr
a
de
d
a
c
c
o
r
di
n
g
t
o
gr
a
de
0,
1
a
n
d
2
[
3]
.
Gr
a
de
0;
n
o
go
i
t
r
e
,
gr
a
de
1;
a
n
e
nl
a
r
ge
d
t
hy
r
o
i
d
t
h
a
t
i
s
p
a
l
p
a
bl
e
b
ut
n
o
t
vi
s
i
b
l
e
w
h
e
n
t
h
e
n
e
c
k
i
s
i
n
t
h
e
n
o
r
m
a
l
po
s
i
t
i
o
n
.
Gr
a
de
2,
a
s
we
ll
i
ng
i
n
t
he
n
e
c
k
t
h
a
t
i
s
vi
s
i
b
l
e
w
h
e
n
t
h
e
ne
c
k
i
s
i
n
a
n
o
r
m
a
l
po
s
i
t
i
o
n
.
A
pr
e
v
a
l
e
nc
e
r
a
t
e
o
f
0
-
4.
9
i
s
c
o
n
s
i
d
e
r
e
d
a
s
n
o
n
e
,
5.
0%
-
19.
9
%
a
s
m
il
d,
20.
0%
-
29.
9
%
a
s
m
o
de
r
a
t
e
,
≥
30.
0%
a
s
s
e
v
e
r
e
I
DD
[
3]
.
2
.
6
.
I
od
i
n
e
in
u
r
in
e
S
pot
ur
i
n
e
s
a
m
p
l
e
s
we
r
e
c
o
l
l
e
c
t
e
d
us
i
ng
ur
i
ne
c
o
n
t
a
i
n
e
r
s
f
r
o
m
a
ll
t
h
e
r
e
s
po
n
de
n
t
s
by
t
r
a
i
n
e
d
m
e
d
i
c
a
l
l
a
b
o
r
a
to
r
y
a
s
s
i
s
s
t
a
n
t
s
.
T
h
e
s
a
m
p
l
e
s
w
e
r
e
ke
pt
i
n
t
h
e
po
l
y
s
t
y
r
e
n
e
c
o
n
t
a
i
ne
r
b
e
f
o
r
e
t
r
a
s
po
r
ted
to
t
h
e
I
DD
L
a
b
o
r
a
to
r
y
i
n
K
o
t
a
Ki
n
a
ba
l
u,
S
a
b
a
h
.
T
h
e
s
a
m
p
l
e
s
we
r
e
s
t
or
e
d
a
t
-
18
o
C
un
t
i
l
a
n
a
ly
s
i
s
.
Ur
i
n
a
r
y
i
o
d
i
ne
de
t
e
r
m
i
na
t
i
o
n
wa
s
do
ne
us
i
ng
i
n
-
h
o
us
e
m
o
d
i
f
ied
m
i
c
r
o
p
l
a
t
e
m
e
t
h
o
d
b
a
s
e
d
o
n
m
a
n
ua
l
d
i
ge
s
t
i
o
n
w
i
t
h
a
m
m
o
ni
u
m
pe
r
s
u
lf
a
t
e
f
o
l
l
o
we
d
by
t
h
e
c
a
l
o
r
i
m
e
t
r
i
c
de
t
e
r
m
i
na
t
i
o
n
o
f
t
h
e
S
a
n
de
l
-
K
o
l
t
h
o
f
f
r
e
a
c
t
i
o
n
by
u
s
i
ng
96
-
m
u
l
t
i
w
e
l
l
p
l
a
t
e
s
a
n
d
a
n
a
b
s
o
r
b
a
n
c
e
m
i
c
r
o
pl
a
t
e
r
e
a
de
r
a
t
405
nm
[
27]
.
P
W
w
i
t
h
ur
i
na
r
y
i
o
d
i
ne
c
o
n
c
e
n
t
r
a
t
i
o
n
(
UI
C
)
o
f
<
150,
150
–
249,
250
–
499
,
a
n
d
≥
500
g/L
we
r
e
c
o
n
s
i
d
e
r
e
d
a
s
ha
vi
n
g
i
ns
u
f
f
i
c
i
e
n
t
,
a
de
qua
t
e
,
m
o
r
e
t
h
a
n
a
de
qua
t
e
,
o
r
e
x
c
e
s
s
i
ve
i
o
d
i
n
e
l
e
v
e
l
s
,
r
e
s
pe
c
t
i
v
e
ly
[
3]
.
2
.
7
.
I
od
i
n
e
in
b
l
ood
Ve
n
o
us
bl
o
o
d
s
a
m
p
l
e
s
(
10.
0
m
l
)
we
r
e
c
o
l
l
e
c
t
e
d
i
n
t
o
pl
a
i
n
va
c
ut
a
i
n
e
r
t
ub
e
s
by
t
r
a
i
n
e
d
s
t
a
f
f
n
ur
s
e
s
.
T
h
e
n
,
t
h
e
bl
o
o
d
s
e
r
u
m
wa
s
s
e
p
a
r
a
t
e
d
a
n
d
k
e
pt
i
n
-
20
0
C
f
r
e
e
z
e
r
a
t
t
h
e
n
e
a
r
by
h
o
s
p
i
t
a
l
l
a
b
o
r
a
tor
y
a
t
th
e
e
n
d
o
f
t
h
e
da
y
by
m
e
d
i
c
a
l
l
a
b
o
r
a
to
r
y
a
s
s
i
s
s
t
a
n
t
s
.
Al
l
s
a
mp
l
e
s
we
r
e
pr
o
pe
r
l
y
pa
c
ke
d
a
n
d
l
a
b
e
l
e
d,
ke
pt
i
n
po
l
y
s
t
y
r
e
n
e
b
o
x
e
s
c
o
n
t
a
i
ni
ng
i
c
e
be
f
o
r
e
b
e
i
ng
t
r
a
n
s
po
r
t
e
d
to
t
h
e
pr
i
v
a
t
e
l
a
b
o
r
a
to
r
y
i
n
S
a
r
a
wa
k
f
o
r
f
ur
t
h
e
r
a
n
a
ly
s
i
s
.
T
h
e
T
hy
r
o
i
d
S
t
i
m
u
l
a
t
i
n
g
Ho
r
m
o
n
e
(
T
S
H)
s
tat
us
wa
s
de
t
e
r
m
i
ne
d
by
us
i
ng
c
o
m
m
e
r
c
i
a
l
A
r
c
hi
t
e
c
t
T
S
H
7K
62
[
28]
.
F
r
e
e
T
4
a
n
d
f
r
e
e
T
3
s
t
a
t
us
we
r
e
de
t
e
r
m
i
ne
d
us
i
ng
c
o
m
m
e
r
c
i
a
l
A
r
c
hi
t
e
c
t
F
r
e
e
T
hy
r
o
xi
ne
(
f
r
e
e
T
4)
7
K
65
[
29]
a
n
d
A
r
c
hi
t
e
c
t
F
r
e
e
T
r
i
i
o
dot
hy
r
o
ni
n
e
(
f
r
e
e
T
3)
7K
63
[
30]
,
r
e
s
pe
c
t
i
ve
l
y
.
T
hy
r
o
pe
r
o
xi
da
s
e
a
n
t
i
b
o
d
y
(
T
P
OA
b
)
s
t
a
t
us
wa
s
de
t
e
r
m
i
ne
d
us
i
ng
c
o
m
m
e
r
c
i
a
l
A
r
c
hi
t
e
c
t
An
t
i
-
T
P
O
2K
47
[
31]
a
n
d
T
hy
r
o
g
l
o
b
u
l
i
n
a
n
t
i
b
o
d
y
(
T
G
Ab
)
s
t
a
t
us
wa
s
d
e
t
e
r
m
i
ne
d
u
s
i
ng
c
o
m
m
e
r
c
i
a
l
A
r
c
hi
t
e
c
t
An
t
i
-
T
g
2K
46
[
32]
.
No
r
m
a
l
r
e
f
e
r
e
nc
e
r
a
n
ge
s
e
s
t
a
bli
s
he
d
by
t
h
e
c
o
m
m
e
r
c
i
a
l
k
i
t
m
a
n
u
f
a
c
t
ur
e
r
we
r
e
us
e
d
f
o
r
a
s
s
e
s
s
i
ng
t
hy
r
o
i
d
d
y
s
f
u
n
c
t
i
o
n
:
T
S
H
(
0.
35
-
4.
94
m
I
U/L
,
f
r
e
e
T
4
(
9.
0
-
19.
1
pm
o
l
/L
)
,
f
r
e
e
T
3
(
2.
63
-
5.
71
p
m
o
l
/L
)
,
T
P
OA
b
(
<
5.
61
I
U/m
L
)
a
n
d
T
G
Ab
(
<
4.
11
I
U/m
L
)
[
28
-
32]
.
2
.
8
.
I
od
i
n
e
in
s
al
t
All
t
he
P
W
we
r
e
a
l
s
o
a
s
ke
d
to
b
r
i
n
g
a
ppr
o
xi
m
a
t
e
l
y
80g
o
f
s
a
l
t
f
r
o
m
t
h
e
i
r
r
e
s
pe
c
t
i
v
e
h
o
m
e
s
in
s
e
l
f
-
s
e
a
l
i
ng
po
l
y
t
h
e
ne
b
a
gs
.
T
he
s
a
m
p
l
e
s
we
r
e
pr
o
pe
r
l
y
pa
c
ke
d
a
n
d
l
a
b
e
l
e
d
b
e
f
o
r
e
b
e
i
ng
t
r
a
n
s
po
r
ted
to
t
h
e
Nut
r
i
t
i
o
n
U
ni
t
,
I
n
s
t
i
t
ut
e
f
o
r
M
e
d
i
c
a
l
R
e
s
e
a
r
c
h
,
K
u
a
l
a
L
u
m
pur
f
o
r
a
n
a
ly
s
i
s
.
T
h
e
pr
e
s
e
n
c
e
o
f
i
o
d
i
ne
i
n
s
a
l
t
wa
s
t
e
s
t
e
d
us
i
n
g
r
a
p
i
d
t
e
s
t
k
i
t
s
(
R
T
K
s
)
d
e
v
e
l
o
pe
d
by
I
n
s
t
i
t
ut
e
f
o
r
M
e
d
i
c
a
l
R
e
s
e
a
r
c
h
.
W
hil
e
,
t
h
e
l
e
v
e
l
o
f
i
o
d
i
ne
c
o
n
c
e
n
t
r
a
t
i
o
n
i
n
s
a
l
t
wa
s
d
e
t
e
r
m
i
ne
d
u
s
i
ng
i
o
d
i
m
e
t
r
i
c
t
i
t
r
a
t
i
o
n
m
e
t
h
o
d
[
33]
.
T
i
t
r
a
t
i
o
n
i
s
o
n
e
o
f
t
h
e
m
o
s
t
a
c
c
ur
a
t
e
a
n
a
l
y
t
i
c
a
l
m
e
t
h
o
ds
a
v
a
il
a
bl
e
a
n
d
t
hi
s
‘
go
l
d
s
t
a
n
da
r
d’
a
na
l
y
t
i
c
a
l
m
e
t
h
o
d
i
s
r
e
c
o
m
m
e
n
de
d
f
o
r
f
a
c
t
or
y
qua
l
i
t
y
a
s
s
ur
a
n
c
e
a
n
d
i
n
r
e
s
e
a
r
c
h
s
t
ud
i
e
s
[
34]
.
Hous
e
h
o
l
ds
c
o
v
e
r
a
ge
w
i
t
h
i
o
d
i
z
e
d
s
a
l
t
a
n
d
m
o
ni
t
o
r
i
ng
qua
l
i
t
y
o
f
s
a
l
t
i
o
d
i
z
a
t
i
o
n
a
r
e
im
po
r
t
a
n
t
ke
y
i
nd
i
c
a
t
o
r
s
i
n
t
he
i
m
p
l
e
m
e
n
t
a
t
i
o
ns
o
f
USI
pr
o
gr
a
m
s
.
T
o
e
n
s
ur
e
s
u
s
t
a
i
n
a
bl
e
I
DD
pr
o
g
r
a
m
m
e
i
n
a
c
o
un
t
r
y
,
i
t
i
s
r
e
c
o
m
m
e
n
de
d
t
h
a
t
a
t
l
e
a
s
t
90%
o
f
h
o
us
e
h
o
l
d
s
us
i
ng
a
de
qua
t
e
l
y
i
o
d
i
s
e
d
s
a
l
t
whi
c
h
c
o
n
t
a
i
n
s
15
pa
r
t
s
pe
r
m
il
li
o
n
o
r
m
o
r
e
[
3
]
.
Evaluation Warning : The document was created with Spire.PDF for Python.
I
S
S
N:
2252
-
8806
I
n
t
.
J
.
P
ubl
i
c
He
a
l
t
h
S
c
i
.
Vo
l
.
8
,
N
o
.
3
,
S
e
p
t
2019
:
307
–
313
310
2
.
9
.
A
n
t
h
r
op
om
e
t
r
ic
m
e
as
u
r
e
m
e
n
t
s
An
t
h
r
o
po
m
e
t
r
i
c
m
e
a
s
ur
e
m
e
n
t
s
we
r
e
we
i
g
h
t
(
kg)
a
n
d
h
e
i
g
h
t
(
c
m
)
.
T
A
NI
T
A
HD
-
319
d
i
g
i
t
a
l
we
i
g
h
t
i
n
g
e
qu
i
p
m
e
n
t
wa
s
us
e
d
t
o
m
e
a
s
ur
e
b
o
dy
we
i
g
h
t
to
t
h
e
n
e
a
r
e
s
t
0.
1
kg.
W
i
t
h
o
u
t
we
a
r
i
ng
s
h
o
e
s
,
r
e
s
po
n
de
n
t
s
a
r
e
r
e
qu
i
r
e
d
t
o
s
t
a
n
d
upr
i
g
h
t
,
h
e
a
d
a
n
d
e
y
e
s
s
t
r
a
i
g
h
t
.
W
hil
e
,
t
h
e
m
e
a
s
ur
e
m
e
n
t
f
o
r
h
e
i
gh
t
we
r
e
t
a
ke
n
t
o
t
h
e
ne
a
r
e
s
t
0.
1
c
m
us
i
ng
S
E
C
A
213
po
r
tabl
e
s
t
a
d
i
o
m
e
t
e
r
.
T
h
e
r
e
s
po
n
de
n
t
s
we
r
e
r
e
qu
i
r
e
d
to
s
t
a
n
d
upr
i
g
h
t
wi
t
h
o
ut
s
h
o
e
s
,
hi
p
s
a
n
d
s
h
o
u
l
de
r
s
i
n
a
s
t
r
a
i
gh
t
l
i
ne
,
he
a
d
a
n
d
e
y
e
i
s
s
t
r
a
i
g
h
t
.
M
e
a
s
ur
e
m
e
n
t
s
we
r
e
do
n
e
i
n
dup
l
i
c
a
t
e
,
a
n
d
t
h
e
m
e
a
n
wa
s
r
e
c
o
r
de
d
a
s
t
h
e
f
i
na
l
r
e
a
d
i
ng.
B
o
d
y
m
a
s
s
i
nde
x
(
B
M
I
)
wa
s
c
a
l
c
u
l
a
t
e
d
b
y
we
i
g
h
t
i
n
k
il
o
gr
a
m
s
d
i
vi
d
e
d
by
h
e
i
g
h
t
i
n
m
e
t
r
e
s
s
qua
r
e
d.
T
h
e
t
e
r
m
u
n
de
r
we
i
g
h
t
r
e
f
e
r
s
t
o
B
M
I
<
18.
5
kg/
m
2
,
n
o
r
m
a
l
(
B
M
I
=
18.
5
–
24.
9
kg/m
2
)
,
whi
l
e
o
v
e
r
we
i
g
h
t
a
n
d
o
b
e
s
e
a
r
e
c
l
a
s
s
i
f
i
e
d
a
s
ha
vi
ng
B
M
I
w
i
t
hi
n
25.
0
–
29.
9
kg/
m
2
a
n
d
≥
30
kg/
m
2
,
r
e
s
pe
c
t
i
ve
ly
[
35]
.
2
.
10
.
Hyp
e
r
/h
yp
ot
h
yr
oid
is
m
as
s
e
s
s
m
e
n
t
S
t
a
f
f
n
ur
s
e
o
f
t
h
e
da
t
a
c
o
l
l
e
c
t
i
o
n
t
e
a
m
c
a
r
r
i
e
d
o
u
t
f
a
c
e
-
to
-
f
a
c
e
i
n
t
e
r
vi
e
ws
w
i
t
h
t
h
e
P
W
a
n
d
c
o
n
duc
t
e
d
phy
s
i
c
a
l
a
s
s
e
s
s
m
e
n
t
to
ga
t
h
e
r
i
nf
o
r
m
a
t
i
o
n
o
n
hy
pe
r
/
hy
po
t
hy
r
o
i
d
i
s
m
s
t
a
t
us
.
T
h
i
s
a
s
s
e
s
s
m
e
n
t
c
o
n
s
i
s
t
s
o
f
12
i
t
e
m
s
w
hi
c
h
c
o
v
e
r
e
d:
a
)
P
r
o
xim
a
l
m
u
s
c
l
e
we
a
k
n
e
s
s
/
hy
pe
r
-
r
e
f
l
e
xi
a
.
b
)
W
a
r
m
/S
we
a
t
pa
l
m
s
.
c
)
H
a
n
d
s
we
a
t
i
n
g
.
d)
F
i
ne
t
r
e
m
o
ur
s
(
f
i
nge
r
)
.
e
)
L
i
d
r
e
t
r
a
c
t
i
o
n
/
li
d
l
a
g
.
f
)
R
e
s
t
i
n
g
t
a
c
hy
c
a
r
d
i
a
.
g)
.
A
pa
t
hy
/
l
e
t
h
a
r
g
y
.
h
)
.
F
a
c
i
a
l
pu
f
f
i
ne
s
s
.
i
)
.
S
l
o
w
s
pe
e
c
h
.
j
)
Ho
a
r
s
e
v
o
i
c
e
.
k)
C
o
l
d
i
n
t
o
l
e
r
a
n
c
e
.
l
)
F
a
t
/
o
b
e
s
e
,
a
n
d
m
)
C
o
ns
t
i
p
a
t
i
o
n
.
2
.
11
.
F
iel
d
i
m
p
l
e
m
e
n
t
at
ion
an
d
e
t
h
ical
c
on
s
id
e
r
at
ion
A
ppr
o
v
a
l
wa
s
o
b
t
a
i
n
e
d
f
r
o
m
t
h
e
M
e
d
i
c
a
l
R
e
s
e
a
r
c
h
a
n
d
E
t
hi
c
C
o
m
mi
t
t
e
e
,
M
i
ni
s
t
r
y
o
f
He
a
l
t
h
M
a
l
a
y
s
i
a
(
N
M
R
R
-
17
-
2932
-
39316)
a
n
d
t
h
e
h
e
a
d
o
f
de
pa
r
t
m
e
n
t
i
n
a
ll
r
e
s
pe
c
t
i
v
e
M
C
HC
s
.
A
t
ot
a
l
o
f
12
da
t
a
c
o
l
l
e
c
t
i
o
n
t
e
a
m
s
we
r
e
f
o
r
m
e
d,
a
n
d
i
n
e
a
c
h
t
e
a
m
,
on
e
n
ut
r
i
t
i
o
ni
s
t
a
s
t
e
a
m
l
e
a
de
r
a
n
d
a
s
s
i
s
t
e
d
by
2
s
t
a
f
f
n
ur
s
e
s
a
n
d
o
n
e
m
e
d
i
c
a
l
l
a
b
o
r
a
to
r
y
a
s
s
i
s
s
t
a
n
t
.
A
t
r
a
i
ni
ng
c
o
ur
s
e
wa
s
c
o
n
duc
t
e
d
to
f
a
mi
li
a
r
i
z
e
t
h
e
t
e
a
m
s
w
i
t
h
t
h
e
que
s
t
i
o
nna
i
r
e
us
e
d
a
n
d
s
a
m
p
l
e
s
c
o
l
l
e
c
t
i
o
n
t
e
c
hni
que
s
.
I
nf
o
r
m
a
t
i
o
n
s
h
e
e
t
s
a
n
d
c
o
n
s
e
n
t
f
o
r
m
s
we
r
e
m
a
de
a
v
a
il
a
bl
e
f
o
r
e
v
e
r
y
r
e
s
po
n
de
n
t
.
Al
l
i
nd
i
vi
du
a
l
i
n
f
o
r
m
a
t
i
o
n
wa
s
ke
pt
c
o
n
f
i
d
e
n
t
i
a
l
.
A
du
m
my
i
de
n
t
i
f
i
c
a
ti
o
n
wa
s
g
i
v
e
n
to
e
a
c
h
r
e
s
po
n
de
n
t
i
n
s
t
e
a
d
o
f
hi
s
o
r
h
e
r
n
a
me
to
m
a
ke
s
ur
e
t
h
e
s
t
ud
y
wa
s
a
n
o
ny
m
o
u
s
.
2
.
12
.
Qu
al
it
y
c
on
t
r
ol
Qua
l
i
t
y
c
o
n
t
r
o
l
o
f
t
h
e
w
h
o
l
e
s
ur
v
e
y
wa
s
do
ne
a
t
va
r
i
o
us
s
t
a
ge
s
o
f
t
h
e
s
t
ud
y
t
o
e
n
s
ur
e
da
t
a
c
o
l
l
e
c
t
e
d
wa
s
o
f
hi
g
h
-
qua
li
t
y
.
Dur
i
n
g
f
i
e
l
d
da
t
a
c
o
l
l
e
c
t
i
o
n
,
t
e
a
m
l
e
a
de
r
wa
s
g
i
ve
n
r
e
s
po
n
s
i
b
il
i
t
y
t
o
c
o
n
duc
t
t
h
e
i
n
t
e
r
vi
e
ws
a
n
d
wa
s
g
i
ve
n
r
e
s
po
n
s
i
b
il
i
t
y
t
o
s
upe
r
vi
s
e
t
h
e
wh
o
l
e
da
t
a
c
o
l
l
e
c
t
i
o
n
pr
o
c
e
s
s
e
s
.
A
t
t
h
e
c
e
n
t
r
a
l
l
e
ve
l
,
t
h
e
pr
o
g
r
e
s
s
o
f
da
t
a
c
o
l
l
e
c
t
i
o
n
f
o
r
a
l
l
M
C
H
C
s
w
a
s
m
o
ni
t
o
r
e
d
c
l
o
s
e
l
y
by
t
h
e
o
f
f
i
c
e
r
f
r
o
m
t
h
e
I
n
s
t
i
t
ut
e
f
o
r
P
ubli
c
He
a
l
t
h
o
n
a
w
e
e
k
ly
b
a
s
i
s
.
I
n
a
dd
i
t
i
o
n
,
a
l
l
t
h
e
s
u
bm
i
t
t
e
d
que
s
t
i
o
nn
a
i
r
e
s
h
a
d
u
n
d
e
r
go
n
e
v
a
r
i
o
us
c
h
e
c
k
s
by
t
h
e
da
t
a
pr
o
c
e
s
s
i
n
g
t
e
a
m
.
2
.
13
.
Da
t
a
e
n
t
r
y
an
d
an
al
ys
is
All
da
t
a
e
n
t
r
y
a
c
t
i
vi
t
i
e
s
we
r
e
c
e
n
t
r
a
l
i
z
e
d
a
t
I
n
s
t
i
t
ut
e
f
o
r
P
ubl
i
c
He
a
l
t
h
w
hi
c
h
s
t
a
r
t
e
d
f
r
o
m
r
e
c
e
i
v
i
ng
que
s
t
i
o
nna
i
r
e
f
r
o
m
t
h
e
f
i
e
l
d
u
n
t
i
l
h
a
n
d
o
v
e
r
o
f
t
h
e
c
l
e
a
n
da
t
a
s
e
t
to
da
t
a
a
n
a
ly
s
i
s
t
e
a
m
.
Da
t
a
pr
o
c
e
s
s
i
n
g
a
c
t
i
vi
t
i
e
s
w
e
r
e
do
n
e
b
a
s
e
d
o
n
t
h
e
t
y
pe
o
f
que
s
t
i
o
nn
a
i
r
e
.
T
h
e
da
t
a
e
n
t
r
y
w
a
s
do
n
e
us
i
ng
a
n
e
x
c
e
l
da
t
a
b
a
s
e
b
y
da
t
a
pun
c
h
e
r
.
All
da
t
a
t
h
a
t
we
r
e
ke
y
e
d
i
n
t
o
da
t
a
b
a
s
e
we
r
e
v
e
r
if
i
e
d
by
a
v
e
r
i
f
i
e
r
.
S
P
S
S
v
e
r
s
i
o
n
21
wa
s
us
e
d
f
o
r
da
t
a
a
n
a
ly
s
i
s
.
T
h
e
da
t
a
wa
s
t
h
e
n
c
h
e
c
ke
d
a
n
d
c
l
e
a
n
e
d
f
o
r
qua
l
i
t
y
c
o
n
t
r
o
l
pur
po
s
e
s
.
De
s
c
r
i
pt
i
ve
s
t
a
t
i
s
t
i
c
wa
s
us
e
d
t
o
i
ll
us
t
r
a
t
e
t
h
e
s
o
c
i
a
l
de
m
o
gr
a
phi
c
o
f
t
h
e
r
e
s
po
n
de
n
t
s
.
An
a
ly
s
i
s
wa
s
do
n
e
a
c
c
o
r
d
i
ng
to
t
h
e
o
bj
e
c
t
i
v
e
s
o
f
t
h
e
s
t
ud
y
.
C
o
m
p
l
e
x
s
a
m
p
l
e
a
na
ly
s
i
s
pr
o
c
e
dur
e
s
we
r
e
us
e
d
i
n
t
h
e
a
n
a
ly
s
i
s
a
n
d
wa
s
c
a
r
r
i
e
d
o
u
t
a
t
95%
c
o
nf
i
de
n
c
e
i
n
t
e
r
v
a
l
.
3.
RE
S
UL
T
S
A
ND
DI
S
CU
S
S
I
ONS
All
s
e
l
e
c
t
e
d
M
C
HC
s
pa
r
t
i
c
i
pa
t
e
d
i
n
t
h
e
s
ur
v
e
y
(
1
00%
r
e
s
p
o
n
s
e
r
a
t
e
)
a
n
d
a
tot
a
l
o
f
677
r
e
s
po
n
de
n
t
s
r
e
s
po
n
de
d
t
o
t
h
e
s
ur
v
e
y
,
w
i
t
h
a
n
o
v
e
r
a
ll
r
e
s
po
ns
e
r
a
t
e
o
f
90.
2%
.
Out
o
f
30
M
C
H
C
s
s
ur
v
e
y
e
d,
a
t
ota
l
o
f
21
M
C
HC
o
b
s
e
r
v
e
d
a
b
e
t
t
e
r
r
e
s
p
o
n
s
e
r
a
t
e
o
f
100%
.
Ho
we
v
e
r
,
t
h
e
r
e
we
r
e
a
f
e
w
M
C
HC
s
s
h
o
we
d
a
r
e
s
po
n
s
e
r
a
t
e
o
f
l
e
s
s
t
h
a
n
50%
s
uc
h
a
s
KK
B
a
t
u
K
a
wa
(
40%
)
,
K
K
S
pa
o
h
(
44%
)
,
K
K
A
s
a
j
a
y
a
(
48%
)
,
a
n
d
KK
T
a
t
a
u
(
48%
)
a
s
s
h
o
wn
i
n
T
a
bl
e
1.
T
h
e
r
e
s
po
n
d
e
n
t
s
c
o
m
pr
i
s
e
d
o
f
677
P
W
a
ge
d
b
e
t
we
e
n
18
t
o
45
y
e
a
r
s
(
m
e
a
n
±
S
D,
28.
6±
5.
3)
a
n
d
a
ppr
o
xi
m
a
t
e
l
y
35%
o
f
t
h
e
r
e
s
po
n
de
n
t
s
we
r
e
f
r
o
m
a
ge
gr
o
up
25
–
29
y
e
a
r
s
o
l
d.
B
y
e
t
hni
c
i
t
y
,
m
a
j
o
r
i
t
y
o
f
t
h
e
r
e
s
po
n
de
n
t
s
we
r
e
M
a
l
a
y
s
(
35.
2%
)
,
f
o
l
l
o
w
e
d
by
I
b
a
n
(
29.
5%
)
a
n
d
C
hi
ne
s
e
(
13.
0%
)
.
I
n
t
e
r
m
s
o
f
gr
a
vi
da
(
n
u
m
be
r
o
f
pr
e
g
n
a
n
c
y
)
,
a
b
o
ut
31
%
o
f
P
W
w
e
r
e
i
n
t
h
e
i
r
s
e
c
o
n
d
gr
a
vi
d
a
a
n
d
28.
5%
we
r
e
i
n
t
h
e
i
r
f
i
r
s
t
gr
a
vi
da
a
s
s
h
o
wn
i
n
T
a
bl
e
2.
Evaluation Warning : The document was created with Spire.PDF for Python.
I
n
t
.
J
.
P
ubl
i
c
He
a
l
t
h
S
c
i
.
I
S
S
N:
2252
-
8806
A
n
as
s
e
s
s
me
nt
of
r
is
k
of
iodi
ne
de
fi
c
ienc
y
among
p
r
e
gnant
w
o
me
n
in
Sar
a
w
a
k
,
M
alays
ia
(
L
im
K
uang
K
uay
)
311
T
a
bl
e
1
.
Num
be
r
o
f
r
e
s
po
n
de
n
t
s
r
e
s
po
n
s
e
d
to
t
h
e
s
ur
v
e
y
,
by
D
i
v
i
s
i
o
n
a
n
d
M
C
HC
s
di
v
is
i
o
n & M
C
H
C
s
numbe
r
of
r
e
s
po
nd
e
nt
s
pe
r
c
e
nt
a
ge
s
(%)
in
v
it
e
d
r
e
s
p
o
ns
e
K
u
c
hi
ng
K
K
P
e
tr
a
J
a
y
a
K
K
B
a
tu
K
a
w
a
M
C
H
C
S
e
ka
ma
M
C
H
C
G
it
a
K
K
K
o
ta
S
e
nt
o
s
a
K
K
I
A
K
o
ta
P
a
da
w
a
n
S
a
ma
r
a
ha
n
K
K
K
o
ta
S
a
ma
r
a
ha
n
M
C
H
C
S
e
bi
s
a
k
K
1M
S
a
ma
r
in
da
h
K
K
A
s
a
ja
y
a
S
e
r
ia
n
K
K
S
ib
ur
a
n
K
K
S
e
r
ia
n
S
r
i
A
ma
n
K
K
S
r
i
A
ma
n
B
e
t
o
ng
K
K
K
a
bo
ng
K
K
S
pa
o
h
S
a
r
ik
e
i
K
K
B
in
ta
ngor
K
K
S
a
r
ik
e
i
M
uka
h
K
K
I
A
D
a
la
t
S
ib
u
K
K
J
a
la
n O
y
a
K
K
L
a
na
ng
K
K
I
A
K
a
n
o
w
it
K
a
pi
t
K
K
K
a
pi
t
K
K
S
o
ng
B
in
tu
lu
K
K
B
in
tu
lu
K
K
T
a
ta
u
M
ir
i
K
K
T
uda
n
K
K
I
A
M
ir
i
K
K
I
A
T
mn
T
unku
L
im
ba
ng
K
K
I
A
L
im
ba
ng
K
K
L
a
w
a
s
25
25
25
25
25
25
25
25
25
25
25
25
25
25
25
25
25
25
25
25
25
25
25
25
25
25
25
25
25
25
24
10
25
25
25
25
25
25
15
12
25
25
25
25
11
25
25
25
25
25
25
25
18
25
12
24
26
25
25
25
96.0
40.0
100.0
100.0
100.0
100.0
100.0
100.0
60.0
48.0
100.0
100.0
100.0
100.0
44.0
100.0
100.0
100.0
100.0
100.0
100.0
100.0
72.0
100.0
48.0
96.0
104.0
100.0
100.0
100.0
T
ot
a
l
750
677
90.2
I
n
c
o
n
duc
t
i
n
g
a
s
t
a
t
e
-
wi
de
s
ur
v
e
y
a
m
o
n
g
P
W
i
n
S
a
r
a
wa
k,
s
a
m
p
li
ng
f
r
o
m
go
v
e
r
nm
e
n
t
M
C
HC
s
wa
s
c
o
n
s
i
de
r
e
d
t
h
e
be
s
t
f
e
a
s
i
b
l
e
a
ppr
o
a
c
h
to
o
b
t
a
i
n
a
r
e
pr
e
s
e
n
t
a
t
i
v
e
s
a
m
p
l
e
o
f
P
W
i
n
S
a
r
a
wa
k.
B
a
s
e
d
o
n
t
h
e
M
i
ni
s
t
r
y
o
f
He
a
l
t
h
,
M
a
l
a
y
s
i
a
a
nn
ua
l
r
e
po
r
t,
t
h
e
nu
m
b
e
r
o
f
go
v
e
r
nm
e
n
t
M
C
H
C
s
r
e
pr
e
s
e
n
t
s
a
b
o
ut
9
8%
o
f
a
ll
t
h
e
M
C
HC
s
i
n
S
a
r
a
wa
k
a
n
d,
t
h
e
de
li
ve
r
y
r
a
t
e
i
n
go
v
e
r
nm
e
n
t
M
C
HC
s
wa
s
m
o
r
e
t
h
a
n
95%
[
18]
.
W
i
t
h
t
hi
s
hi
g
h
r
a
t
e
s
,
a
r
e
pr
e
s
e
n
t
a
t
i
v
e
s
a
m
p
l
e
o
f
P
W
i
n
S
a
r
a
wa
k
c
a
n
b
e
o
b
t
a
i
n
e
d
f
r
o
m
t
he
go
v
e
r
nm
e
n
t
M
C
HC
s
.
Due
t
o
t
h
e
s
m
a
ll
pr
o
po
r
t
i
o
n
o
f
pr
i
va
t
e
M
C
HC
s
i
n
S
a
r
a
wa
k,
we
de
c
i
de
d
t
o
e
x
c
l
ude
pr
i
va
t
e
M
C
H
C
s
i
n
t
h
e
s
u
r
v
e
y
a
n
d
t
hi
s
e
x
c
l
u
s
i
o
n
wo
ul
d
n
o
t
m
a
ke
a
ny
s
i
g
ni
f
i
c
a
n
t
e
f
f
e
c
t
o
n
t
h
e
f
i
nd
i
ngs
.
T
h
e
s
t
r
e
n
gt
h
o
f
t
h
e
s
t
udy
i
s
t
h
e
us
e
o
f
a
ppr
o
p
r
i
a
t
e
s
a
m
p
li
ng
m
e
t
h
o
d
whi
c
h
i
nv
o
l
ve
d
a
r
e
pr
e
s
e
n
t
a
t
i
v
e
s
a
m
p
l
e
o
f
r
e
s
po
n
d
e
n
t
s
f
r
o
m
a
ll
d
i
v
i
s
i
o
ns
in
S
a
r
a
wa
k.
T
h
e
s
a
m
p
l
e
s
s
i
z
e
c
a
l
c
u
l
a
t
i
o
n
a
l
s
o
t
a
k
e
i
n
t
o
c
o
n
s
i
de
r
a
t
i
o
n
o
f
f
e
w
f
a
c
t
o
r
s
s
uc
h
a
s
pr
e
v
a
l
e
n
c
e
,
m
a
r
g
i
n
o
f
e
r
r
o
r
,
de
s
i
g
n
e
f
f
e
c
t
a
n
d
e
s
t
i
m
a
t
e
d
r
e
s
po
n
s
e
r
a
t
e
[
25]
.
T
h
e
r
e
s
po
n
s
e
r
a
t
e
o
f
90.
2%
i
n
t
hi
s
s
t
ud
y
w
a
s
c
o
n
s
i
de
r
e
d
hi
g
h
.
T
h
e
go
o
d
r
e
s
p
o
n
s
e
r
a
t
e
c
o
u
l
d
be
due
t
o
s
e
v
e
r
a
l
f
a
c
t
o
r
s
i
nc
l
ud
i
n
g
go
o
d
c
o
l
l
a
b
o
r
a
ti
o
n
s
a
n
d
s
uppo
r
t
s
f
r
o
m
S
a
r
a
wa
k
S
t
a
t
e
He
a
l
t
h
De
pa
r
t
m
e
n
t
(
S
S
HD
)
.
I
n
a
dd
i
t
i
o
n
,
t
h
e
da
t
a
c
o
l
l
e
c
t
i
o
n
wa
s
c
o
n
d
uc
t
e
d
by
S
S
HD
s
t
a
f
f
s
w
h
o
a
r
e
w
e
l
l
ve
r
s
e
w
i
t
h
t
h
e
l
o
c
a
l
lan
gua
g
e
a
n
d
c
u
l
t
ur
e
.
Ho
we
v
e
r
,
t
h
e
r
e
w
e
r
e
a
f
e
w
M
C
H
C
s
s
h
o
we
d
l
o
w
r
e
s
po
ns
e
r
a
t
e
s
,
e
s
pe
c
i
a
ll
y
f
r
o
m
s
m
a
ll
M
C
HC
s
.
I
t
’
s
n
o
t
e
d
t
h
a
t
dur
i
n
g
t
h
e
pe
r
i
o
d
o
f
da
t
a
c
o
l
l
e
c
t
i
o
n
,
i
n
t
h
e
s
e
M
C
HC
s
w
i
t
h
l
o
w
r
e
s
po
n
s
e
r
a
t
e
s
,
t
h
e
r
e
h
a
s
be
e
n
qu
i
t
e
a
n
u
m
be
r
o
f
P
W
w
h
o
s
e
ge
s
t
a
t
i
o
na
l
pe
r
i
o
ds
h
a
s
b
e
e
n
e
x
c
e
e
d
i
ng
12
we
e
ks
(
f
i
r
s
t
tr
i
mes
t
e
r
)
wh
e
n
t
h
e
y
c
a
m
e
f
o
r
c
h
e
c
k
up.
T
h
us
,
t
h
e
y
a
r
e
n
o
t
e
l
i
g
i
b
l
e
f
o
r
t
h
e
s
ur
v
e
y
.
Evaluation Warning : The document was created with Spire.PDF for Python.
I
S
S
N:
2252
-
8806
I
n
t
.
J
.
P
ubl
i
c
He
a
l
t
h
S
c
i
.
Vo
l
.
8
,
N
o
.
3
,
S
e
p
t
2019
:
307
–
313
312
T
a
bl
e
2
.
S
o
c
i
o
-
de
m
o
gr
a
phi
c
c
h
a
r
a
c
t
e
r
i
s
t
i
c
s
o
f
pr
e
g
n
a
n
t
wo
m
e
n
i
n
S
a
r
a
wa
k
c
ha
r
a
c
t
e
r
is
ti
c
s
numbe
r
of
r
e
s
po
nd
e
nt
s
pe
r
c
e
nt
a
ge
s
(
%
)
O
ve
r
a
ll
677
100.0
A
ge
(
y
e
a
r
s
)
≤25
25
-
29
30
-
34
≥35
178
232
188
79
26.3
34.3
27.8
11.7
E
th
ni
c
it
y
I
ba
n
M
a
la
y
C
hi
ne
s
e
B
id
a
y
uh
M
e
la
na
u
O
th
e
r
s
200
238
88
49
41
61
29.5
35.2
13.0
7.2
6.1
9.0
G
r
a
v
id
a
(
numb
e
r
of
pr
e
gna
nc
y
)
1
2
3
≥4
193
208
130
146
28.5
30.7
19.2
21.6
4.
CONC
L
USI
ON
T
hi
s
I
DD
s
t
ud
y
a
m
o
n
g
P
W
a
im
e
d
a
t
pr
o
vi
d
i
ng
p
o
pul
a
t
i
o
n
-
b
a
s
e
d
da
t
a
o
n
t
h
e
I
DD
s
t
a
t
us
o
f
P
W
i
n
S
a
r
a
wa
k.
T
h
e
s
ur
v
e
y
wa
s
p
l
a
nn
e
d
w
i
t
h
t
h
e
go
a
l
o
f
o
b
t
a
i
ni
ng
t
h
e
l
a
t
e
s
t
da
t
a
to
s
uppor
t
M
i
ni
s
t
r
y
o
f
H
e
a
l
t
h
,
M
a
l
a
y
s
i
a
i
n
r
e
vi
e
w
i
ng
a
n
d
p
l
a
nni
ng
t
h
e
I
DD
pr
ogr
a
m
i
n
S
a
r
a
wa
k.
T
o
e
n
s
ur
e
t
h
e
da
t
a
c
o
l
l
e
c
t
e
d
a
r
e
o
f
hi
g
h
qua
l
i
t
y
a
n
d
v
a
li
d
i
t
y
,
a
l
l
t
h
e
ne
c
e
s
s
a
r
y
s
t
e
ps
h
a
v
e
be
e
n
t
a
ke
n
,
s
t
a
r
t
i
n
g
f
r
o
m
p
l
a
nni
ng,
de
t
e
r
m
i
na
t
i
o
n
o
f
s
a
m
p
l
e
s
i
z
e
,
s
a
m
p
li
ng
de
s
i
g
n
,
da
t
a
c
o
l
l
e
c
t
i
o
n
t
e
c
hni
que
s
,
a
n
d
qua
li
t
y
c
o
n
t
r
o
l
o
f
da
t
a
c
o
l
l
e
c
t
e
d.
T
h
e
f
i
nd
i
ng
s
o
f
t
hi
s
s
t
udy
w
il
l
e
n
a
bl
e
t
h
e
M
i
n
i
s
t
r
y
o
f
He
a
l
t
h
,
M
a
l
a
y
s
i
a
to
e
v
a
l
u
a
t
e
t
h
e
i
m
pa
c
t
o
f
t
h
e
USI
a
m
o
n
g
pr
e
g
n
a
n
t
wo
m
e
n
i
n
S
a
r
a
w
a
k
a
n
d
m
a
ke
n
e
c
e
s
s
a
r
y
im
pr
o
v
e
m
e
n
t
to
t
h
e
pr
e
s
e
n
t
n
a
t
i
o
n
a
l
pr
o
gr
a
m
m
e
.
AC
K
NOWL
E
DGE
M
E
NT
S
T
h
e
r
e
s
e
a
r
c
h
wa
s
f
u
n
de
d
by
t
h
e
M
i
ni
s
t
r
y
o
f
He
a
l
t
h
M
a
l
a
y
s
i
a
.
W
e
w
i
s
h
t
o
a
c
kn
o
wl
e
dg
e
t
h
e
D
i
r
e
c
t
o
r
Ge
n
e
r
a
l
o
f
He
a
l
t
h
M
a
l
a
y
s
i
a
f
o
r
pe
r
m
i
s
s
i
o
n
t
o
pu
bli
s
h
t
hi
s
p
a
pe
r
.
S
pe
c
i
a
l
t
h
a
n
ks
t
o
S
a
r
a
wa
k
S
t
a
t
e
He
a
l
t
h
De
pa
r
t
m
e
n
t
f
o
r
pr
o
vi
d
i
ng
h
e
a
l
t
h
s
t
a
f
f
s
t
o
i
nv
o
l
v
e
i
n
t
hi
s
s
ur
ve
y
.
RE
F
E
R
E
NC
E
S
[1
]
A
m
e
r
i
c
an
T
h
y
ro
i
d
A
s
s
o
c
i
at
i
o
n
.
H
y
p
o
t
h
y
ro
i
d
i
s
m:
A
b
o
o
k
l
e
t
f
o
r
p
at
i
en
t
an
d
t
h
ei
r
fa
m
i
l
i
e
s
.
Fa
l
l
s
Ch
u
r
c
h
:
A
m
er
i
ca
n
Th
yr
o
i
d
A
s
s
o
c
i
a
t
i
o
n
,
.
p
.
5
9
8
-
6
0
6
,
2
0
1
3
.
[2
]
Ri
s
t
i
c
-
M
e
d
i
c
D
,
G
l
i
b
e
t
i
c
M
.
I
o
d
i
n
e
:
P
h
y
s
i
o
l
o
g
y
i
n
en
cy
cl
o
p
ed
i
a
o
f
f
eed
an
d
h
e
al
t
h
.
U
n
i
v
e
rs
i
t
y
o
f
B
el
g
ra
d
e,
Be
l
g
rad
e,
.
p
.
4
4
4
-
4
5
,
2
0
1
6
.
[3
]
W
H
O
/
U
N
I
CE
F/
I
CC
I
D
D
.
A
s
s
e
s
s
men
t
o
f
i
o
d
i
n
e
d
e
fi
ci
e
n
cy
d
i
s
o
rd
e
rs
an
d
m
o
n
i
t
o
r
i
n
g
t
h
e
i
r
e
l
i
m
i
n
at
i
o
n
.
3
rd
e
d
.
Fr
an
ce:
W
o
r
l
d
H
e
al
t
h
O
rg
an
i
zat
i
o
n
,
.
p
.
7
-
1
0
,
2
0
0
7
.
[4
]
Z
i
mme
r
m
an
n
MB.
T
h
e
ro
l
e
o
f
i
o
d
i
n
e
i
n
h
u
m
an
g
r
o
w
t
h
an
d
d
e
v
el
o
p
me
n
t
.
S
em
i
n
a
r
i
n
ce
l
l
&
D
ev
B
i
o
l
.
,
2
2
:
6
4
5
-
52
,
2
0
1
1
.
[5
]
H
e
t
z
e
l
B.
V
an
q
u
i
s
h
i
n
g
i
o
d
n
e
d
e
f
i
c
i
en
cy
d
i
s
o
r
d
e
rs
.
La
n
cet
.
,
3
8
1
,
2
0
1
3
.
[6
]
T
ru
m
p
ff
C,
S
c
h
e
p
p
e
r
J
D
,
T
affo
r
e
a
u
,
O
y
en
H
V
,
v
an
d
e
rfa
ei
l
l
i
e
J
,
V
an
d
e
v
i
j
v
e
re
S.
Mi
l
d
i
o
d
i
n
e
d
e
f
i
c
i
en
cy
i
n
p
re
g
n
a
n
cy
i
n
E
u
ro
p
e
an
d
i
t
s
c
o
n
s
e
q
u
e
n
ce
s
fo
r
c
o
g
n
i
t
i
v
e
an
d
p
s
y
c
h
o
m
o
t
o
r
d
e
v
el
o
p
me
n
t
o
f
c
h
i
l
d
ren
:
A
rev
i
ew
.
J.
Tr
a
ce
E
l
em
M
ed
&
B
i
o
l
.,
2
7
:
1
7
4
-
8
3
,
2
0
1
3
.
[7
]
Z
i
mme
r
m
an
n
MB.
T
h
e
e
ff
ec
t
s
o
f
i
o
d
i
n
e
d
e
f
i
c
i
en
cy
i
n
p
re
g
n
an
cy
an
d
i
n
fan
cy
.
Pa
ed
i
a
t
r
P
er
i
n
E
p
i
d
em
i
o
l
.
,
26
(s
u
p
p
l
1
):
1
0
8
-
1
7
,
2
0
1
2
.
[8
]
Bo
o
n
s
t
ra
A
M,
j
a
i
s
w
al
N
.
I
o
d
i
n
e
d
e
fi
c
i
en
cy
i
n
p
r
e
g
n
a
n
cy
,
i
n
fan
cy
an
d
ch
i
l
d
r
en
an
d
i
t
s
c
o
n
s
e
q
u
en
ce
s
fo
r
b
rai
n
d
ev
e
l
o
p
men
t
.
B
es
t
P
r
a
ct
R
es
Cl
i
n
E
n
d
o
c
r
i
n
o
l
M
et
a
b
.
,
2
4
:
2
9
-
3
8
,
2
0
1
0
.
[9
]
Caro
n
P
.
N
eu
ro
co
g
n
i
t
i
v
e
o
u
t
c
o
me
s
o
f
c
h
i
l
d
r
e
n
s
ec
o
n
d
ar
y
t
o
m
i
l
d
i
o
d
i
n
e
d
e
fi
ci
e
n
cy
i
n
p
r
e
g
n
an
t
w
o
me
n
.
A
n
n
E
n
d
o
c
r
i
n
o
l
.
,
7
6
:
2
4
8
-
5
2
,
2
0
1
5
.
[1
0
]
A
n
afo
r
o
g
l
u
I
,
A
l
g
u
n
E
,
I
n
cec
a
y
i
r
O
,
T
o
p
b
a
s
M,
E
r
d
o
g
an
MF.
I
o
d
i
n
e
s
t
at
u
s
am
o
n
g
p
re
g
n
an
t
w
o
m
en
a
ft
e
r
m
an
d
at
o
r
y
s
al
t
i
o
d
i
s
at
i
o
n
.
B
r
J
Nu
t
r
.
,
1
1
5
:
4
0
5
-
1
0
,
2
0
1
6
.
[1
1
]
A
n
d
e
rs
s
o
n
M,
d
e
B
e
n
o
i
s
t
B,
Ro
g
e
r
L
.
E
p
i
d
em
i
o
l
o
g
y
o
f
i
o
d
i
n
e
d
e
f
i
c
i
en
cy
:
Sal
t
i
o
d
i
s
at
i
o
n
an
d
i
o
d
i
n
e
s
t
s
t
u
s
.
B
es
t
P
r
a
ct
R
es
Cl
i
n
E
n
d
o
cr
i
n
o
l
M
et
a
b
.
,
2
4
:
1
-
1
1
,
2
0
1
0
.
[1
2
]
G
re
g
o
r
y
G
,
ID
D
el
i
mi
n
at
i
o
n
i
n
Ru
s
s
i
a:
c
h
a
l
l
en
g
e
s
an
d
s
o
l
u
t
i
o
n
.
Z
u
ri
ch
:
ID
D
Ne
w
s
l
et
t
e
r
;
May
.
p
.
1
-
6
,
2
0
0
8
.
[1
3
]
U
N
I
CE
F.
S
u
s
t
ai
n
ab
l
e
o
f
i
o
d
i
n
e
d
e
fi
ci
e
n
cy
.
N
ew
Y
o
r
k
:
T
h
e
U
n
i
t
ed
n
at
i
o
n
s
o
f
Ch
i
l
d
r
e
n
’s
F
u
n
d
,
.
p
.
5
-
7
,
2008
.
[1
4
]
L
i
m
K
K
,
J
am
b
ai
E
,
Ch
an
Y
Y
,
T
e
h
CH
,
H
as
i
m
ah
I
,
L
i
m
K
H
,
K
ee
CC.
I
o
d
i
n
e
s
t
at
u
s
af
t
e
r
a
3
-
y
e
ar
u
n
i
v
e
rs
al
s
al
t
i
o
d
i
s
at
i
o
n
i
n
Sara
w
a
k
,
Ma
l
a
y
s
i
a
.
In
t
J
P
u
b
H
ea
l
t
h
R
es
.
,
5
(2
):
6
3
1
-
3
6
,
2
0
1
5
.
Evaluation Warning : The document was created with Spire.PDF for Python.
I
n
t
.
J
.
P
ubl
i
c
He
a
l
t
h
S
c
i
.
I
S
S
N:
2252
-
8806
A
n
as
s
e
s
s
me
nt
of
r
is
k
of
iodi
ne
de
fi
c
ienc
y
among
p
r
e
gnant
w
o
me
n
in
Sar
a
w
a
k
,
M
alays
ia
(
L
im
K
uang
K
uay
)
313
[1
5
]
K
i
y
u
A
.
Io
d
i
n
e
d
e
fi
ci
e
n
cy
d
i
s
o
r
d
e
rs
i
n
Sara
w
ak
,
Mal
a
y
s
i
a
.
A
s
i
a
P
a
c
J
Cl
i
n
Nu
t
r
.
,
7
(3
/
4
):
2
5
6
-
6
1
,
1
9
9
8
.
[1
6
]
Ru
s
i
d
a
h
S,
W
an
N
aza
i
m
o
o
n
W
M,
A
h
m
ad
A
l
i
Z
,
N
o
r
S
y
a
m
l
i
n
a
CA
R,
Su
h
ai
l
a
A
G
,
T
ah
i
r
A
.
I
o
d
i
n
e
d
e
f
i
c
i
en
cy
s
t
a
t
u
s
an
d
i
o
d
i
s
e
d
s
al
t
co
n
s
u
m
p
t
i
o
n
i
n
Ma
l
a
y
s
i
a
:
F
i
n
d
i
n
g
s
fro
m
a
n
at
i
o
n
al
i
o
d
i
n
e
d
e
fi
ci
e
n
cy
d
i
s
o
r
d
e
rs
s
u
rv
ey
.
A
s
i
a
P
a
c
J
Cl
i
n
Nu
t
r
.
,
1
9
(1
4
):
5
7
8
-
8
5
,
2
0
1
0
.
[1
7
]
G
o
v
e
r
n
me
n
t
o
f
Mal
a
y
s
i
a.
F
o
o
d
A
c
t
an
d
R
e
g
u
l
at
i
o
n
.
K
u
a
l
a
L
u
m
p
u
r:
M
D
C
P
u
b
l
i
s
h
e
rs
,
.
p
.
1
3
-
1
5
,
2
0
1
3
.
[1
8
]
Saraw
a
k
St
at
e
H
e
a
l
t
h
D
e
p
art
men
t
.
Su
r
v
ey
o
f
i
o
d
i
n
e
d
e
fi
c
i
en
cy
d
i
s
o
r
d
e
rs
amo
n
g
p
reg
n
a
n
t
w
o
men
i
n
Sara
w
a
k
,
St
a
t
e
H
e
a
l
t
h
D
e
p
art
me
n
t
o
f
Sara
w
a
k
.
p
.
2
4
-
7
,
2
0
1
6
.
[1
9
]
K
u
an
g
K
u
a
y
L
i
m,
Y
i
n
g
Y
i
n
g
Ch
an
,
Ch
i
e
n
H
u
ey
T
eh
,
H
as
i
m
a
h
I
s
m
a
i
l
,
Rafi
d
ah
Y
u
s
o
f,
J
a
m
ai
l
Mu
h
i
,
K
u
a
n
g
H
o
c
k
L
i
m
,
Fo
o
L
e
n
g
H
u
at
Fo
o
.
i
o
d
i
n
e
s
t
at
u
s
am
o
n
g
p
reg
n
a
n
t
w
o
men
fro
m
s
e
l
ec
t
e
d
ru
ra
l
d
i
v
i
s
i
o
n
s
i
n
Sab
ah
,
Mal
a
y
s
i
a
.
A
s
i
a
P
a
c
J
Cl
i
n
Nu
t
r
.
,
2
6
(5
):
8
6
1
-
6
6
,
2
0
1
7
.
[2
0
]
T
o
rre
E
M,
A
l
v
ar
e
z
E
D
,
A
rt
al
A
R
,
G
u
t
i
e
rr
e
z
L
S,
c
ab
a
l
l
e
ro
MG
R,
B
l
an
co
J
A
,
N
a
y
a
L
D
,
F
e
rn
a
n
d
e
z
J
CF.
I
o
d
i
n
e
n
u
t
ri
t
i
o
n
i
n
p
reg
n
a
n
t
w
o
me
n
i
n
t
h
e
O
v
i
e
d
o
ar
e
a.
I
s
i
o
d
i
n
e
s
u
p
p
l
eme
n
t
at
i
o
n
r
e
q
u
i
r
ed
?.
E
n
d
o
cr
i
n
o
l
Nu
t
r
.
2
0
1
4
;
6
1
(8
):
4
0
4
-
09.
[2
1
]
Cal
d
w
el
l
K
L
.
Mak
h
mu
d
o
v
A
.
E
l
y
E
.
J
o
n
e
s
RL
.
W
a
n
g
RY
.
I
o
d
i
n
e
St
at
u
s
o
f
t
h
e
U
.
S
.
Po
p
u
l
at
i
o
n
,
N
at
i
o
n
a
l
H
eal
t
h
an
d
N
u
t
ri
t
i
o
n
E
x
ami
n
at
i
o
n
Su
r
v
ey
,
2
0
0
5
–
2
0
0
6
an
d
2
0
0
7
–
2
0
0
8
.
Th
yr
o
i
d
.
,
2
1
(
4
):
4
1
9
-
2
7
,
2
0
1
1
.
[2
2
]
Marc
h
i
o
n
i
E
,
F
u
m
aro
l
a
A
,
Ca
l
v
a
n
e
s
e
A
,
Pi
cci
ri
l
l
i
F,
T
o
mm
as
i
V
,
C
u
g
i
n
i
P,
U
l
i
s
s
e
S
,
fan
el
l
i
FR,
D
’
A
r
m
i
en
t
o
M.
I
o
d
i
n
e
d
e
fi
ci
e
n
cy
i
n
p
r
e
g
n
an
t
w
o
me
n
re
s
i
d
i
n
g
i
n
an
ar
e
a
w
i
t
h
ad
e
q
u
at
e
i
o
d
i
n
e
i
n
t
ak
e.
Nu
t
r
i
t
i
o
n
.
,
2
4
:
4
5
8
-
61
,
2
0
0
8
.
[2
3
]
W
o
rl
d
H
e
al
t
h
O
rg
an
i
zat
i
o
n
.
T
rai
n
i
n
g
fo
r
m
i
d
-
l
ev
e
l
m
a
n
ag
e
rs
(ML
M)
:
T
h
e
E
P
I
c
o
v
e
rag
e
s
u
r
v
ey
.
G
e
n
ev
a:
W
o
r
l
d
H
ea
l
t
h
O
r
g
a
n
i
z
a
t
i
o
n
,
.
p
.
6
-
1
5
,
2
0
0
8
.
[2
4
]
N
ai
n
g
N
N
.
A
p
rac
t
i
c
a
l
g
u
i
d
e
o
n
d
e
t
e
r
mi
n
at
i
o
n
o
d
s
am
p
l
e
s
i
z
e
i
n
h
e
al
t
h
s
ci
e
n
ce
s
re
s
e
ar
c
h
.
K
o
t
a
Bh
aru
:
U
n
i
v
e
r
s
i
t
i
S
ci
en
ce
Ma
l
a
y
s
i
a,
.
p
.
1
-
20
,
2
0
1
0
.
[2
5
]
N
ai
n
g
L
,
W
i
n
n
T
,
Ru
s
l
i
BN
.
Pra
c
t
i
c
al
i
s
s
u
e
s
i
n
c
a
l
c
u
l
at
i
n
g
t
h
e
s
am
p
l
e
s
i
ze
fo
r
p
rev
al
en
ce
s
t
u
d
i
e
s
.
A
r
ch
O
r
o
f
a
c
S
ci
.
,
1
:
9
-
1
4
,
2
0
0
6
.
[2
6
]
Co
n
d
o
D
,
H
u
y
h
n
D
,
A
n
d
e
rs
o
n
A
J
,
Sk
e
aff
S,
R
y
an
P
mak
ri
d
e
s
M,
e
t
.
al
.
Io
d
i
n
e
s
t
at
u
s
o
f
p
re
g
n
an
t
w
o
me
n
i
n
So
u
t
h
A
u
s
t
ral
i
a
aft
e
r
m
an
d
at
o
r
y
i
o
d
i
n
e
fo
rt
i
f
i
c
at
i
o
n
o
f
b
r
e
ad
a
n
d
t
h
e
r
eco
mme
n
d
at
i
o
n
fo
r
i
o
d
i
n
e
s
u
p
p
l
emen
t
at
i
o
n
.
M
a
t
er
n
Ch
i
l
d
Nu
t
r
.
,
1
3
(
4
):
1
-
8
,
2
0
1
6
.
[2
7
]
H
u
s
n
i
za
H
,
W
an
N
aza
i
m
o
o
n
W
M.
A
c
o
s
t
e
ff
ec
t
i
v
e
mo
d
i
fi
e
d
m
i
c
r
o
me
t
h
o
d
fo
r
me
as
u
r
i
n
g
u
ri
n
e
i
o
d
i
n
e
.
Tr
o
p
i
c
M
ed
.
,
2
3
(1
):
1
0
9
-
1
5
,
2
0
0
6
.
[2
8
]
A
b
b
o
t
t
l
ab
o
rat
o
ri
e
s
.
.
A
r
c
h
i
t
ec
t
T
SH
7
K
6
2
.
L
o
n
g
f
o
r
d
:
A
b
b
o
t
t
I
re
l
a
n
d
D
i
a
g
n
o
s
t
i
c
s
.
p
.
1
-
7
,
2015
.
[2
9
]
A
b
b
o
t
t
l
ab
o
rat
o
ri
e
s
.
A
r
c
h
i
t
ec
t
Fr
ee
T
4
7
K
6
5
.
L
o
n
g
fo
r
d
:
A
b
b
o
t
t
I
rel
an
d
D
i
ag
n
o
s
t
i
c
s
.
p
.
1
-
6.
2
0
1
7
.
[3
0
]
A
b
b
o
t
t
l
ab
o
rat
o
ri
e
s
.
A
r
c
h
i
t
ec
t
Fr
ee
T
3
7
K
6
3
.
L
o
n
g
fo
r
d
:
A
b
b
o
t
t
I
rel
an
d
D
i
ag
n
o
s
t
i
c
s
.
,
p
.
1
-
5
,
2015.
[3
1
]
A
b
b
o
t
t
l
ab
o
rat
o
ri
e
s
.
A
r
c
h
i
t
ec
t
A
n
t
i
-
T
PO
2
K
4
7
.
U
S
A
:
A
b
b
o
t
t
l
ab
o
rat
o
ri
e
s
.
p
.
1
-
6
,
2
0
0
5
.
[3
2
]
A
b
b
o
t
t
l
ab
o
rat
o
ri
e
s
.
A
r
c
h
i
t
ec
t
A
n
t
i
-
T
g
2
K
4
6
.
U
S
A
:
A
b
b
o
t
t
l
ab
o
rat
o
ri
e
s
.
p
.
1
-
7
,
2
0
0
6
.
[3
3
]
Su
l
l
i
v
an
K
M,
H
o
u
s
t
o
n
R,
G
o
rs
t
e
i
n
J
,
Ce
rv
i
n
s
k
as
J
.
Mo
n
i
t
o
ri
n
g
u
n
i
v
e
rs
al
s
al
t
i
o
d
i
zat
i
o
n
p
ro
g
ra
mme
s
.
A
t
l
a
n
t
a
:
M
i
cr
o
n
u
t
r
i
en
t
In
i
t
i
a
t
i
ve
,
.
p
.
1
5
-
8
,
1
9
9
5
.
[3
4
]
M
y
e
rs
N
M,
St
r
y
d
o
m
E
E
,
S
w
ee
t
J
,
S
w
ee
t
C,
Sp
o
h
r
e
r
R
,
A
l
i
D
h
a
n
s
a
y
M
,
L
i
e
b
e
r
m
a
n
M
.
Sa
l
t
PA
D
:
a
n
ew
an
a
l
y
t
i
c
al
t
o
o
l
f
o
r
m
o
n
i
t
o
r
i
n
g
s
al
t
i
o
d
i
zat
i
o
n
i
n
l
o
w
r
e
s
o
u
r
ce
s
e
t
t
i
n
g
.
Na
n
o
b
i
o
m
ed
.
,
3
(5
):
1
-
9
,
2
0
1
6
.
[3
5
]
D
o
h
e
rt
y
D
A
,
Mag
a
n
E
F,
Fran
ci
s
J
,
Mo
rri
s
o
n
J
C,
N
ew
n
h
a
m
J
P.
Pr
e
-
p
reg
n
a
n
cy
b
o
d
y
m
as
s
i
n
d
e
x
an
d
p
r
e
g
n
an
cy
o
u
t
co
me
s
.
In
t
J
G
yn
a
eco
l
O
b
s
t
et
.
,
9
5
:
2
4
2
–
4
7
,
2
0
0
6
.
Evaluation Warning : The document was created with Spire.PDF for Python.