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In
s
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-
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8]
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9]
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n
hy
po
s
pa
d
i
a
s
is
f
o
un
d
w
i
t
h
o
t
h
e
r
c
r
i
t
e
r
i
a
of
DSD
i
nc
l
ud
i
ng
u
n
de
s
c
e
n
de
d
t
e
s
t
i
s
,
it
r
e
qui
r
e
s
an
e
v
a
l
ua
t
i
o
n
w
i
t
h
ka
r
y
o
t
y
pe
s
c
r
e
e
ni
ng
[
1]
.
T
h
e
r
e
h
a
s
b
e
e
n
no
pr
e
v
a
l
e
n
c
e
s
t
udy
on
hy
po
s
pa
d
i
a
s
w
i
t
h
un
de
s
c
e
n
de
d
t
e
s
t
i
s
in
I
n
do
n
e
s
i
a
.
T
hi
s
pr
e
v
a
l
e
n
c
e
s
t
ud
y
a
im
e
d
to
de
t
e
r
m
i
ne
t
h
e
pr
e
v
a
l
e
nc
e
of
hy
po
s
pa
d
i
a
s
w
i
t
h
u
n
de
s
c
e
n
de
d
t
e
s
t
i
s
in
t
he
De
pa
r
t
m
e
n
t
of
S
ur
ge
r
y
M
o
h
a
mm
a
d
Ho
e
s
i
n
Ho
s
pi
t
a
l
P
a
l
e
m
ba
n
g
in
I
n
do
n
e
s
i
a
.
2.
RE
S
E
AR
CH
M
E
T
HO
D
T
hi
s
pr
e
v
a
l
e
nc
e
s
t
ud
y
h
a
s
b
e
e
n
do
n
e
in
M
e
d
ica
l
R
e
c
o
r
ds
De
p
a
r
t
m
e
n
t
of
M
o
h
a
mm
a
d
Ho
e
s
i
n
Ho
s
pi
t
a
l
P
a
l
e
m
ba
ng
f
r
o
m
J
u
ly
2018
to
F
e
b
r
ua
r
y
2019.
T
h
e
s
a
m
p
l
e
of
t
hi
s
s
t
ud
y
w
a
s
t
h
o
s
e
f
u
l
f
il
li
ng
t
h
e
i
n
c
l
u
s
i
o
n
c
r
i
t
e
r
i
a
w
hi
c
h
we
r
e
a
l
l
pa
t
i
e
n
t
s
s
us
pe
c
t
e
d
of
hy
po
s
pa
d
i
a
s
in
t
he
De
pa
r
t
m
e
n
t
of
S
ur
ge
r
y
M
o
h
a
m
m
a
d
Ho
e
s
i
n
Ho
s
p
i
t
a
l
P
a
l
e
m
ba
ng
dur
i
n
g
t
h
e
pe
r
i
o
d
of
2016
–
2017,
a
n
d
pa
t
i
e
n
t
s
w
i
t
h
c
o
m
p
l
e
t
e
d
m
e
d
i
c
a
l
r
e
po
r
t
s
.
T
h
e
da
t
a
us
e
d
in
t
hi
s
s
t
ud
y
wa
s
s
e
c
o
n
da
r
y
da
t
a
o
b
t
a
i
n
e
d
f
r
o
m
M
e
d
i
c
a
l
R
e
c
o
r
ds
De
pa
r
t
m
e
n
t
of
M
o
h
a
mm
a
d
Ho
e
s
i
n
Ho
s
p
i
t
a
l
.
T
h
e
da
t
a
wa
s
de
r
i
ve
d
f
r
o
m
t
h
e
m
e
d
i
c
a
l
r
e
c
o
r
ds
of
pa
t
i
e
n
t
s
wh
o
wa
s
t
r
e
a
t
e
d
by
t
h
e
De
pa
r
t
m
e
n
t
of
S
ur
ge
r
y
M
o
h
a
mm
a
d
Ho
e
s
i
n
Ho
s
p
i
t
a
l
P
a
l
e
m
ba
n
g
dur
i
ng
2016
–
2017
pe
r
i
o
d.
T
h
e
da
t
a
we
r
e
a
n
a
ly
z
e
d
us
i
ng
uni
va
r
i
a
t
e
a
n
a
ly
s
i
s
to
pr
o
du
c
e
de
s
c
r
i
pt
i
v
e
t
a
bl
e
w
i
t
h
s
e
ve
r
a
l
pr
e
de
t
e
r
m
i
ne
d
va
r
i
a
bl
e
s
i
nc
l
ud
i
ng
t
h
e
a
ge
gr
o
up
of
t
h
e
hy
po
s
pa
d
i
a
s
pa
t
i
e
n
t
,
t
h
e
hy
po
s
pa
d
i
a
s
t
y
pe
,
hi
s
t
o
r
y
of
u
n
de
s
c
e
n
de
d
t
e
s
ti
s
in
t
h
e
hy
po
s
pa
d
i
a
s
pa
t
i
e
n
t
s
,
a
n
d
t
y
pe
s
of
t
h
e
u
n
de
s
c
e
n
d
e
d
t
e
s
t
i
s
on
hy
po
s
pa
d
i
a
s
p
a
t
i
e
n
t
s
w
i
t
h
u
n
de
s
c
e
n
d
e
d
t
e
s
t
i
s
.
T
h
e
pr
oto
c
o
l
ha
s
b
e
e
n
a
ppr
o
v
e
d
by
e
t
hi
c
a
l
c
o
m
mi
t
t
e
e
of
F
a
c
u
l
t
y
of
M
e
d
i
c
i
ne
S
r
i
w
ij
a
y
a
U
ni
ve
r
s
i
t
y
.
3.
RE
S
UL
T
S
A
ND
DI
S
CU
S
S
I
ONS
F
r
o
m
t
h
e
183
hy
po
s
pa
d
i
a
s
pa
t
i
e
n
t
s
in
M
o
h
a
mm
a
d
Ho
e
s
i
n
Ho
s
p
i
t
a
l
dur
i
ng
2016
–
2017
pe
r
i
o
d,
103
m
e
t
t
h
e
i
nc
l
us
i
o
n
c
r
i
t
e
r
i
a
.
3.
1.
Age
gr
ou
p
s
of
h
yp
os
p
ad
ias
p
at
ien
t
T
h
e
pa
t
i
e
n
t
s
we
r
e
d
i
vi
de
d
i
n
t
o
s
e
v
e
r
a
l
a
ge
gr
o
ups
,
n
a
m
e
ly
:
0
–
5
m
o
n
t
hs
,
6
–
11
m
o
n
t
hs
,
1
–
5
y
e
a
r
s
o
l
d,
6
–
10
y
e
a
r
s
o
l
d,
11
–
14
y
e
a
r
s
o
l
d,
a
nd
15
–
19
y
e
a
r
s
o
l
d.
Dur
i
n
g
2016
–
2017,
hy
po
s
pa
d
i
a
s
pa
t
i
e
n
t
on
t
h
e
a
ge
gr
o
up
of
1
–
5
y
e
a
r
s
o
l
d
wa
s
t
h
e
m
o
s
t
c
o
m
m
o
n
in
t
h
e
De
p
a
r
t
m
e
n
t
of
S
ur
ge
r
y
M
o
h
a
mm
a
d
Ho
e
s
i
n
Ho
s
pi
t
a
l
w
i
t
h
51
pa
t
i
e
n
t
s
(
49.
5%
)
.
It
wa
s
f
o
l
l
o
we
d
by
6
–
10
y
e
a
r
s
o
l
d
w
i
t
h
34
pa
t
i
e
n
t
s
(
33%
)
,
0
–
5
m
o
n
t
hs
w
i
t
h
8
pa
t
i
e
n
t
s
(
8%
)
,
11
–
14
y
e
a
r
s
o
l
d
w
i
t
h
7
pa
t
i
e
n
t
s
(
7%
)
,
a
n
d
6
–
11
m
o
n
t
hs
w
i
t
h
2
pa
t
i
e
n
t
s
(
1.
9
%
)
.
T
h
e
l
e
a
s
t
c
o
m
m
o
n
a
ge
gr
o
up
of
t
h
e
hy
po
s
pa
d
i
a
s
pa
t
i
e
n
t
wa
s
15
–
19
y
e
a
r
s
o
l
d
w
i
t
h
1
pa
t
i
e
nt
(
1%
)
.
T
a
bl
e
1
s
h
o
ws
t
h
e
gr
o
ups
of
a
ge
a
m
o
n
g
pa
t
i
e
n
t
s
.
T
a
bl
e
1.
Hy
po
s
pa
d
i
a
s
b
a
s
e
d
on
a
ge
gr
o
ups
in
De
pa
r
t
m
e
n
t
of
S
ur
ge
r
y
M
o
ha
m
m
a
d
Ho
e
s
i
n
Ho
s
p
i
t
a
l
2016
–
2
017
A
ge
gr
o
up
n
%
0
–
5
mo
nt
hs
8
7.8
6
–
11
mo
nt
hs
2
1.9
1
–
5
y
e
a
r
s
51
49.5
6
–
10
y
e
a
r
s
34
33.0
11
–
14
y
e
a
r
s
7
6.8
15
–
19
y
e
a
r
s
1
1.0
T
ot
a
l
103
100
T
h
e
m
o
s
t
c
o
m
m
o
n
a
ge
gr
o
u
p
of
hy
po
s
pa
d
i
a
s
pa
t
i
e
n
t
s
in
M
o
h
a
mm
a
d
Ho
e
s
i
n
Ho
s
p
i
t
a
l
dur
i
n
g
2016
–
2017
pe
r
i
o
d
wa
s
1
–
5
y
e
a
r
s
o
l
d
w
i
t
h
51
pa
t
i
e
n
t
s
(
49.
5%
)
.
T
h
e
o
p
t
i
m
a
l
a
ge
of
ge
ni
t
a
l
o
pe
r
a
t
i
o
n
is
b
e
t
we
e
n
6
to
12
m
o
n
t
hs
[
10
]
.
If
t
h
e
o
pe
r
a
t
i
o
n
c
o
ul
d
n
o
t
be
do
n
e
e
a
r
l
i
e
r
or
t
h
e
a
n
o
m
a
l
y
wa
s
f
o
un
d
w
he
n
pa
t
i
e
n
t
wa
s
1
y
e
a
r
o
l
d
or
a
b
o
v
e
,
t
h
e
o
pp
o
r
t
uni
t
y
to
h
a
v
e
t
h
e
o
pe
r
a
t
i
o
n
at
t
h
e
a
ge
of
3
–
4
y
e
a
r
s
o
l
d
is
s
t
i
ll
po
s
s
i
bl
e
[
11
]
.
H
o
we
v
e
r
,
in
de
v
e
l
o
p
i
ng
c
o
un
t
r
i
e
s
due
to
l
a
t
e
a
wa
r
e
n
e
s
s
,
i
g
n
o
r
a
n
c
e
of
t
h
e
a
n
o
m
a
ly
,
a
n
d
u
n
a
f
f
o
r
da
bi
li
t
y
to
h
a
v
e
t
h
e
o
pe
r
a
t
i
o
n
,
t
h
e
a
ve
r
a
ge
a
ge
of
hy
po
s
pa
d
i
a
s
p
a
t
i
e
n
t
s
b
r
o
ugh
t
to
h
o
s
p
i
t
a
l
is
5
y
e
a
r
s
o
l
d
[
12
]
.
T
h
e
s
e
m
a
y
a
l
s
o
be
t
h
e
r
e
a
s
o
n
s
to
why
t
he
m
o
s
t
c
o
m
m
o
n
a
ge
gr
o
u
p
of
hy
po
s
pa
d
i
a
s
pa
t
i
e
n
t
is
1
–
5
y
e
a
r
s
o
l
d.
3.
2.
Cl
as
s
if
i
c
at
ion
of
h
yp
os
p
ad
ias
B
a
s
e
d
on
t
h
e
c
l
a
s
s
i
f
i
c
a
t
i
o
n
of
hy
po
s
pa
d
i
a
s
,
t
h
e
m
o
s
t
c
o
m
m
o
n
t
y
p
e
of
hy
po
s
pa
d
i
a
s
wa
s
s
e
v
e
r
e
hy
po
s
pa
d
i
a
s
w
i
t
h
71
pa
t
i
e
n
t
s
(
68.
9
%
)
.
M
e
a
nwhil
e
,
18
pa
t
i
e
n
t
s
(
17.
5
%
)
h
a
v
e
m
o
de
r
a
t
e
or
m
i
dd
l
e
hy
po
s
pa
d
i
a
s
,
a
n
d
14
pa
t
i
e
n
t
s
(
13.
6
%
)
h
a
v
e
m
il
d
hypo
s
pa
d
i
a
s
.
T
a
bl
e
2
r
e
v
e
a
l
s
t
h
e
s
e
ve
r
i
t
y
a
m
o
n
g
pa
t
i
e
n
t
s
.
Evaluation Warning : The document was created with Spire.PDF for Python.
I
S
S
N:
2252
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8806
I
n
t
.
J.
P
ubl
i
c
He
a
l
t
h
S
c
i
.
Vo
l
.
8,
N
o
.
2
,
J
un
e
2019
:
1
5
8
–
16
2
160
T
a
bl
e
2.
Di
vi
de
d
s
e
v
e
r
i
t
y
of
hy
po
s
pa
d
i
a
s
T
y
p
e
of
h
y
p
o
s
pa
di
a
s
n
%
M
il
d
H
y
p
o
s
pa
di
a
s
14
13.6
M
id
dl
e
H
y
p
o
s
pa
di
a
s
18
17.5
S
e
ve
r
e
H
y
p
o
s
pa
di
a
s
71
68.9
T
ot
a
l
103
100%
M
a
j
o
r
i
t
y
of
s
e
ve
r
e
hy
po
s
pa
d
i
a
in
t
h
e
De
pa
r
t
m
e
n
t
of
S
ur
ge
r
y
M
o
h
a
mm
a
d
Ho
e
s
i
n
Ho
s
p
i
t
a
l
we
r
e
pe
n
o
s
c
r
ot
a
l
hy
po
s
pa
d
i
a
s
w
hi
c
h
m
e
a
t
us
ur
e
h
t
r
a
e
x
ter
n
us
l
o
c
a
t
e
d
b
e
t
we
e
n
pr
o
xi
m
a
l
s
ha
f
t
of
pe
ni
s
a
n
d
s
c
r
ot
um
.
T
hi
s
r
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s
u
l
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c
o
r
r
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s
p
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a
k
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et
a
l.
r
e
s
e
a
r
c
h
whi
c
h
r
e
po
r
t
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d
s
e
v
e
r
e
hy
po
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pa
d
i
a
s
as
m
o
r
e
c
o
m
m
o
n
t
h
a
n
m
o
de
r
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t
e
hy
po
s
pa
d
i
a
s
a
n
d
mi
l
d
hy
po
s
pa
d
i
a
s
[
13
]
.
Ho
we
v
e
r
,
t
hi
s
r
e
s
u
l
t
d
i
f
f
e
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e
po
r
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o
t
h
e
r
li
t
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r
a
t
ur
e
wh
e
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h
e
m
o
s
t
c
o
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m
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y
pe
of
hy
po
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i
a
s
wa
s
m
il
d
hy
po
s
pa
d
i
a
s
w
i
t
h
50%
or
65
–
70
%
of
a
l
l
hy
po
s
pa
d
i
a
s
c
a
s
e
s
in
wo
r
l
d
[
1
,
14
]
.
T
h
e
n
u
m
be
r
of
mi
l
d
or
d
i
s
t
a
l
hy
po
s
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d
i
a
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p
a
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h
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ma
l
l
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in
M
o
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a
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Ho
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p
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P
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t
be
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a
us
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by
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he
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s
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t
s
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s
pa
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a
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i
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o
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ng
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o
s
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t
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a
mi
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or
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Dr
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o
h
a
m
m
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d
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s
i
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p
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l
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a
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m
ba
n
g
is
t
h
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t
o
p
h
o
s
p
i
t
a
l
in
t
h
e
r
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g
i
o
n
so
s
e
v
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r
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hy
p
o
s
pa
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c
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we
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to
t
h
e
h
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s
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t
a
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m
o
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.
3.
3.
Hi
s
t
or
y
of
u
n
d
e
s
c
e
n
d
e
d
t
e
s
t
is
in
h
yp
os
p
ad
i
as
p
at
ient
s
T
h
e
m
a
j
o
r
i
t
y
of
hy
po
s
pa
d
i
a
s
pa
t
i
e
n
t
s
d
i
d
n
o
t
h
a
v
e
u
n
de
s
c
e
n
de
d
t
e
s
t
i
s
w
i
t
h
96
pa
t
i
e
n
t
s
(
93.
2%
)
,
whil
e
t
h
e
ot
h
e
r
7
pa
t
i
e
n
t
s
(
6.
8%
)
h
a
v
e
a
hi
s
t
o
r
y
of
un
de
s
c
e
n
de
d
t
e
s
t
i
s
.
T
a
bl
e
3
de
s
c
r
i
be
s
t
h
e
his
to
r
y
of
un
de
s
c
e
n
de
d
t
e
s
t
i
s
a
m
o
n
g
pa
t
i
e
n
t
s
.
T
a
bl
e
3.
Hi
s
t
or
y
of
u
n
de
s
c
e
n
de
d
t
e
s
t
i
s
in
hy
po
s
pa
d
i
a
s
pa
t
i
e
n
t
s
H
is
t
o
r
y
of
U
nd
e
s
c
e
nd
e
d
t
e
s
ti
s
n
%
H
a
v
e
7
6.8
No
96
93.2
T
ot
a
l
103
100
C
o
m
pa
r
e
d
to
ot
h
e
r
s
t
udi
e
s
of
hy
po
s
pa
d
i
a
s
w
i
t
h
un
de
s
c
e
n
de
d
t
e
s
t
i
s
,
t
h
i
s
s
t
ud
y
ha
s
s
im
il
a
r
r
e
s
u
l
t
.
In
t
h
e
s
t
udy
by
I
t
e
s
a
ko
et
al
.
,
f
r
o
m
466
hy
po
s
pa
d
i
a
s
pa
t
i
e
n
t
s
,
29
pa
t
i
e
n
t
s
(
6.
2%
)
h
a
v
e
c
o
n
ge
ni
t
a
l
u
n
de
s
c
e
n
de
d
t
e
s
t
i
s
a
n
d
15
pa
t
i
e
n
t
s
(
3.
2%
)
h
a
ve
a
c
qu
i
r
e
d
u
n
d
e
s
c
e
n
d
e
d
t
e
s
t
i
s
[
13
]
.
An
d
f
r
o
m
Wu
et
al.
r
e
s
e
a
r
c
h
,
26
of
352
hy
po
s
pa
d
i
a
s
pa
t
i
e
n
t
s
(
7.
3%
)
h
a
v
e
u
n
de
s
c
e
n
de
d
t
e
s
t
i
s
[
15
]
.
3.
4.
T
yp
e
of
u
n
d
e
s
c
e
n
d
e
d
t
e
s
t
is
an
d
h
yp
os
p
ad
ia
s
in
h
yp
os
p
ad
ias
p
a
t
ient
s
wi
t
h
u
n
d
e
s
c
e
n
d
e
d
t
e
s
t
is
Of
t
h
e
s
e
v
e
n
hy
po
s
pa
d
i
a
s
pa
t
i
e
n
t
s
w
i
t
h
u
nde
s
c
e
n
de
d
t
e
s
t
i
s
,
n
o
t
o
nl
y
t
h
r
e
e
hy
po
s
pa
d
i
a
s
pa
t
i
e
n
t
s
(
42.
85%
)
wi
t
h
bil
a
t
e
r
a
l
u
n
de
s
c
e
n
de
d
t
e
s
tes
,
b
ut
a
l
s
o
t
h
r
e
e
pa
t
i
e
n
t
s
(
42.
85%
)
wi
t
h
l
e
f
t
un
d
e
s
c
e
n
de
d
t
e
s
t
i
s
.
On
t
h
e
o
t
h
e
r
ha
n
d,
o
nl
y
o
n
e
pa
t
i
e
n
t
(
14.
3%
)
wi
t
h
hi
s
t
o
r
y
of
r
i
g
h
t
un
de
s
c
e
n
de
d
t
e
s
t
i
s
is
s
h
o
w
n
in
T
a
bl
e
4.
T
a
bl
e
4.
C
l
a
s
s
i
f
i
c
a
t
i
o
n
of
u
n
de
s
c
e
n
de
d
t
e
s
t
i
s
in
hypo
s
pa
d
i
a
s
pa
t
i
e
n
t
s
w
i
t
h
hi
s
t
o
r
y
of
u
n
de
s
c
e
n
de
d
t
e
s
t
i
s
T
y
p
e
s
of
U
nd
e
s
c
e
nd
e
d
T
e
s
ti
s
n
%
B
il
a
t
e
r
a
l
3
42.85
L
e
f
t
3
42.85
R
ig
ht
1
14.3
T
ot
a
l
7
100%
T
a
bl
e
5
s
h
o
ws
t
h
a
t
f
i
ve
pa
t
i
e
n
t
s
(
71
.
4
%
)
wi
t
h
s
e
v
e
r
e
hy
po
s
pa
d
i
a
s
.
It
wa
s
t
h
e
m
o
s
t
c
o
m
m
o
n
t
y
pe
s
of
hy
po
s
pa
d
i
a
s
a
m
o
n
g
hy
po
s
pa
d
i
a
s
pa
t
i
e
n
t
s
w
i
t
h
hi
s
t
o
r
y
of
u
n
d
e
s
c
e
n
de
d
t
e
s
t
i
s
.
M
e
a
n
w
hil
e
,
n
o
t
o
nl
y
o
ne
pa
t
i
e
n
t
(
14
.
3
%
)
h
a
s
mild
hy
po
s
pa
d
i
a
s
,
b
ut
a
l
s
o
m
o
de
r
a
t
e
hy
po
s
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d
i
a
s
o
nl
y
h
a
v
e
o
n
e
pa
t
i
e
n
t
(
14
.
3%
)
.
T
a
bl
e
5.
T
y
pe
of
hy
po
s
pa
d
i
a
s
w
i
t
h
hi
s
t
o
r
y
of
un
d
e
s
c
e
n
de
d
t
e
s
t
i
s
T
y
p
e
of
H
y
p
o
s
pa
di
a
s
N
%
M
il
d
H
y
p
o
s
pa
di
a
s
1
14
.
3
M
o
de
r
a
te
H
y
p
o
s
pa
di
a
s
1
14
.
3
S
e
ve
r
e
H
y
p
o
s
pa
di
a
s
5
71
.
4
T
ot
a
l
7
100%
Evaluation Warning : The document was created with Spire.PDF for Python.
I
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P
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2252
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8806
P
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pos
padias
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161
T
hi
s
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s
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is
in
li
ne
w
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Wu
et
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s
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a
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/pr
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a
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a
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u
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s
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e
n
de
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t
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s
t
i
s
w
a
s
m
o
s
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c
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m
o
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on
pa
t
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t
s
w
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po
s
t
e
r
i
o
r
hy
po
s
pa
d
i
a
s
t
h
a
n
t
h
e
o
t
h
e
r
s
[
1
5]
.
S
i
mi
l
a
r
r
e
s
u
l
t
w
a
s
r
e
po
r
t
e
d
by
I
t
e
s
a
k
o
et
al.
S
t
udy
w
h
e
r
e
c
o
n
ge
ni
t
a
l
u
n
de
s
c
e
n
de
d
t
e
s
t
i
s
a
n
d
a
c
qu
i
r
e
d
u
n
de
s
c
e
n
de
d
t
e
s
t
i
s
a
pp
e
a
r
e
d
m
o
s
t
on
pr
o
xi
m
a
l
or
s
e
v
e
r
e
hy
po
s
pa
d
i
a
s
[
13
]
.
A
c
c
o
r
d
i
ng
to
T
a
i
s
e
n
et
al.
s
t
ud
y
,
r
i
s
k
of
u
n
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s
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d
e
d
t
e
s
t
i
s
in
hy
po
s
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d
i
a
s
pa
t
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n
t
s
is
hi
g
h
e
r
on
pa
t
i
e
n
t
s
w
i
t
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p
r
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xi
m
a
l
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s
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i
a
s
,
h
o
we
v
e
r
t
h
e
r
i
s
k
f
a
c
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or
s
a
s
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o
c
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t
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t
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t
i
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t
i
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u
n
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lea
r
so
t
h
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r
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a
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n
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s
c
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n
d
e
d
t
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s
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s
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t
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ppe
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r
e
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o
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m
a
l
hy
po
s
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d
i
a
s
t
h
a
n
t
h
e
ot
h
e
r
ty
pe
s
is
s
t
i
ll
u
n
k
n
o
wn
[
13
,
16
]
.
3.
5.
Age
gr
ou
p
in
h
yp
os
p
ad
ias
p
a
t
ient
s
wi
t
h
u
n
d
e
s
c
e
n
d
e
d
t
e
s
t
is
T
a
bl
e
6
r
e
v
e
a
l
s
t
h
a
t
t
he
m
o
s
t
c
o
m
m
o
n
a
ge
gr
o
up
of
hy
po
s
pa
d
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a
s
pa
t
i
e
n
t
s
w
i
t
h
u
n
de
s
c
e
n
de
d
t
e
s
t
i
s
wa
s
1
–
5
y
e
a
r
s
o
l
d
w
i
t
h
5
pa
t
i
e
n
t
s
(
71
.
4%
)
.
T
a
bl
e
6.
A
ge
gr
o
ups
of
hy
po
s
pa
d
i
a
s
pa
t
i
e
n
t
s
w
i
t
h
hi
s
t
o
r
y
of
u
n
de
s
c
e
n
de
d
t
e
s
t
i
s
A
ge
gr
o
ups
n
%
0
–
6
mo
nt
hs
1
14
.
3
1
–
5
y
e
a
r
s
5
71
.
4
6
–
10
y
e
a
r
s
1
14
.
3
T
ot
a
l
7
100%
D
i
a
g
n
o
s
i
s
a
n
d
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m
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a
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17
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.
If
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40
[
18]
.
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s
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d
[
19
]
.
4.
CONC
L
USI
ON
P
r
e
v
a
l
e
n
c
e
of
hy
po
s
pa
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De
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s
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s
p
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l
dur
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g
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–
2017
pe
r
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s
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(
6.
8%
)
o
u
t
of
103
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po
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85%
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–
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r
s
w
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5
pa
t
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s
(
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h
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m
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y
pe
of
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a
s
w
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t
h
5
pa
t
i
e
n
t
s
(
71.
4%
)
.
RE
F
E
R
E
NC
E
S
[1
]
Mu
rp
h
y
J
P.
H
y
p
o
s
p
ad
i
as
.
I
n
:
H
o
l
c
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m
b
G
W
,
Mu
rp
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J
P,
O
s
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J
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s
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Ped
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:
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;
2
0
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4
.
p.
7
9
4
–
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0
8
.
[2
]
G
al
l
en
t
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n
e
M
L
,
Mo
r
ey
A
F,
T
h
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p
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Jr
I
M.
H
y
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s
p
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as
:
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co
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p
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0
0
1
A
p
r
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;
5
7
(4
):
7
8
8
-
90.
[3
]
A
l
b
e
rt
N,
U
l
r
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c
h
s
C,
G
l
ü
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r
S,
H
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O,
Si
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k
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H
,
Mi
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d
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b
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Br
o
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l
J.
E
t
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i
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cl
as
s
i
fi
c
at
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n
of
s
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v
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h
y
p
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p
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as
:
i
m
p
l
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c
at
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o
n
s
fo
r
p
ro
g
n
o
s
i
s
an
d
m
a
n
ag
emen
t
.
Th
e
Jo
u
r
n
a
l
of
p
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a
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r
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cs
.
1
9
9
7
Se
p
1
;
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1
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2
.
[4
]
Sp
ri
n
g
e
r
A,
V
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D
en
H
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k
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t
M,
Bau
m
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S.
W
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r
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d
w
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rev
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of
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[5
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a
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[6
]
D
u
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.
Ch
ara
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Sa
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.
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6.
[7
]
Mari
t
s
k
a
Z,
San
t
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A,
A
ri
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M
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,
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Pro
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8
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[8
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E
l
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J
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A
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s
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P
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I
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162
[9
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L
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H
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1
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.
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JU
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Bh
at
A.
E
x
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n
d
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d
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ral
m
o
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i
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zat
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in
i
n
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s
ed
p
l
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u
r
e
t
h
ro
p
l
as
t
y
fo
r
s
ev
e
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y
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s
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0
0
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p
1
;
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5.
[1
3
]
I
t
e
s
ak
o
T,
N
ara
K,
Mat
s
u
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Mat
s
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a
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a
K.
A
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q
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h
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