I
nte
rna
t
io
na
l J
o
urna
l
o
f
E
lect
rica
l a
nd
Co
m
p
ute
r
E
ng
in
ee
ring
(
I
J
E
CE
)
Vo
l.
9
,
No
.
2
,
A
p
r
il
201
9
,
p
p
.
1
0
2
8
~
1
0
3
5
I
SS
N:
2
0
8
8
-
8708
,
DOI
: 1
0
.
1
1
5
9
1
/
i
j
ec
e
.
v9
i
2
.
pp
1
0
2
8
-
1035
1028
J
o
ur
na
l ho
m
ep
a
g
e
:
h
ttp
:
//ia
e
s
co
r
e
.
co
m/
jo
u
r
n
a
ls
/in
d
ex
.
p
h
p
/
I
JE
C
E
No
ise reduc
tion i
n ECG
sig
na
ls for
bio
-
tele
m
etry
V.
J
a
g
a
n Na
v
ee
n
1
,
K
.
M
ur
a
li K
rish
na
2
,
K
.
Ra
j
a
Ra
j
es
w
a
ri
3
1
De
p
a
rtme
n
t
o
f
El
e
c
tro
n
ics
a
n
d
C
o
m
m
u
n
ica
ti
o
n
E
n
g
in
e
e
rin
g
,
G
M
R
In
stit
u
te o
f
T
e
c
h
n
o
lo
g
y
,
Ra
ja
m
,
In
d
ia
2
De
p
a
rtme
n
t
o
f
ECE
,
A
NIT
S
,
V
ish
a
k
h
a
p
a
tn
a
m
,
In
d
ia
3
De
p
a
rtme
n
t
o
f
ECE
,
G
VP
CEW
,
V
ish
a
k
h
a
p
a
t
n
a
m
,
In
d
ia
Art
icle
I
nfo
AB
ST
RAC
T
A
r
ticle
his
to
r
y:
R
ec
eiv
ed
J
u
n
1
9
,
2
0
1
8
R
ev
i
s
ed
Sep
2
0
,
2
0
1
8
A
cc
ep
ted
Ok
t
1
1
,
2
0
1
8
In
Bio
tele
m
e
tr
y
,
Bio
m
e
d
ica
l
sig
n
a
l
su
c
h
a
s
EC
G
is
e
x
tre
m
e
l
y
i
m
p
o
rtan
t
in
th
e
d
iag
n
o
sis
o
f
p
a
ti
e
n
ts
in
re
m
o
te
lo
c
a
ti
o
n
a
n
d
is
re
c
o
rd
e
d
c
o
m
m
o
n
l
y
w
it
h
n
o
ise
.
C
o
n
si
d
e
re
d
a
tt
e
n
t
io
n
is
re
q
u
ired
f
o
r
a
n
a
ly
sis
o
f
ECG
sig
n
a
l
to
f
in
d
th
e
p
a
th
o
-
p
h
y
sio
lo
g
y
a
n
d
sta
tu
s
o
f
p
a
ti
e
n
t
.
In
th
is
p
a
p
e
r,
L
M
S
a
n
d
RL
S
a
lg
o
rit
h
m
a
re
i
m
p
le
m
e
n
ted
o
n
a
d
a
p
ti
v
e
F
IR
f
il
ter
f
o
r
re
d
u
c
in
g
p
o
w
e
r
li
n
e
in
terf
e
re
n
c
e
(5
0
Hz
)
a
n
d
(AWG
N
)
n
o
ise
o
n
ECG
si
g
n
a
ls
.
T
h
e
EC
G
sig
n
a
ls
a
re
ra
n
d
o
m
l
y
c
h
o
se
n
f
ro
m
M
IT
_
BIH
d
a
ta
b
a
se
a
n
d
d
e
-
n
o
i
sin
g
u
sin
g
a
lg
o
rit
h
m
s.
T
h
e
p
e
a
k
s
a
n
d
h
e
a
rt
ra
te
o
f
th
e
EC
G
sig
n
a
l
a
r
e
e
sti
m
a
ted
.
T
h
e
m
e
a
su
re
m
e
n
ts
a
re
tak
e
n
in
term
s
o
f
S
ig
n
a
l
P
o
w
e
r,
No
ise
P
o
w
e
r
a
n
d
M
e
a
n
S
q
u
a
re
Err
o
r.
K
ey
w
o
r
d
s
:
E
C
G
s
i
g
n
a
ls
L
MS
al
g
o
r
ith
m
Me
an
Sq
u
ar
e
E
r
r
o
r
p
o
w
er
lin
e
i
n
ter
f
er
e
n
ce
R
L
S a
lg
o
r
it
h
m
Co
p
y
rig
h
t
©
201
9
In
stit
u
te o
f
A
d
v
a
n
c
e
d
E
n
g
i
n
e
e
rin
g
a
n
d
S
c
ien
c
e
.
Al
l
rig
h
ts
re
se
rv
e
d
.
C
o
r
r
e
s
p
o
nd
ing
A
uth
o
r
:
V.
J
ag
an
Nav
ee
n
,
Dep
ar
t
m
en
t o
f
E
lectr
o
n
ics a
n
d
C
o
m
m
u
n
icat
io
n
E
n
g
i
n
ee
r
in
g
,
GM
R
I
n
s
tit
u
te
o
f
T
ec
h
n
o
lo
g
y
,
R
aj
am
,
I
n
d
ia
.
E
m
ail: j
ag
an
n
a
v
ee
n
8
0
1
@
g
m
a
il.c
o
m
1.
I
NT
RO
D
UCT
I
O
N
T
h
e
E
lectr
o
C
ar
d
io
g
r
am
(
E
C
G)
p
r
o
d
u
ce
s
elec
tr
ical
s
i
g
n
a
ls
o
f
th
e
ea
ch
ca
r
d
iac
c
y
cle.
I
n
th
e
ca
r
d
iac
c
y
cle
ea
ch
ev
e
n
t
h
a
s
its
o
w
n
s
ig
n
i
f
ica
n
ce
to
s
tu
d
y
t
h
e
b
eh
av
io
u
r
o
f
p
atien
t
ca
r
d
iac
p
ath
o
p
h
y
s
io
lo
g
y
,
Gen
er
all
y
E
C
G
s
ig
n
al
s
ar
e
B
io
elec
tr
ical
s
i
g
n
al
w
h
ich
g
iv
es
t
h
e
elec
tr
ical
ac
ti
v
it
y
o
f
h
ea
r
t
v
er
s
u
s
t
i
m
e.
T
h
er
ef
o
r
e
it
is
v
er
y
i
m
p
o
r
tan
t
to
d
iag
n
o
s
e
f
o
r
an
al
y
s
i
n
g
h
ea
r
t
f
u
n
ct
io
n
[
1
]
.
T
h
e
B
io
elec
tr
o
d
es
ar
e
p
lace
d
o
n
th
e
s
k
i
n
o
f
t
h
e
p
atie
n
t
to
ac
q
u
ir
e
E
C
G
s
i
g
n
als.
T
h
e
p
ac
em
ak
er
s
ar
e
lo
ca
ted
i
n
t
h
e
u
p
p
er
p
ar
t
o
f
th
e
r
ig
h
t
atr
iu
m
.
I
t
f
ir
es
elec
tr
ical
p
u
ls
e
s
to
th
e
n
er
v
es
to
s
ti
m
u
la
te
th
e
co
n
tr
ac
tio
n
p
h
ase.
T
h
ese
p
u
l
s
es
ex
ten
d
o
v
er
t
h
e
atr
ial
w
all
s
an
d
ac
ti
v
ate
ca
r
d
iac
m
u
s
cles
to
co
n
tr
ac
t.
T
h
e
E
C
G
an
d
p
o
w
er
-
li
n
e
s
i
g
n
al
’
s
f
r
eq
u
en
c
y
r
an
g
e
is
t
y
p
icall
y
0
.
0
5
to
1
0
0
Hz
an
d
5
0
Hz
s
o
,
E
C
G
s
ig
n
als
s
e
n
s
iti
v
e
to
th
e
p
o
w
er
li
n
e
s
i
g
n
als
i
n
th
e
r
a
n
g
e
ar
o
u
n
d
5
0
Hz
w
h
ic
h
ar
e
ca
u
s
i
n
g
i
n
ter
f
er
en
ce
[
2
]
.
5
0
Hz
P
L
I
N
w
i
ll
in
ter
r
u
p
t
t
h
e
P
an
d
Q
w
av
e
s
o
f
t
h
e
E
C
G
s
ig
n
al.
Mo
s
t
o
f
Asi
an
r
eg
io
n
s
,
Do
m
esti
c
an
d
h
o
s
p
ital
p
o
w
er
li
n
e
ar
e
i
n
th
e
r
an
g
e
o
f
5
0
Hz.
So
th
e
f
r
eq
u
en
c
y
co
m
p
o
n
e
n
t
s
ass
o
ciate
d
in
E
C
G
th
at
is
5
0
Hz
ar
e
ef
f
ec
ted
b
y
t
h
e
p
o
w
er
lin
e
s
ig
n
als
ca
u
s
in
g
in
ter
f
er
en
ce
i
n
E
C
G.
B
u
t
lack
o
f
p
o
w
er
lin
e
q
u
alit
y
t
h
e
p
o
w
er
s
i
g
n
a
ls
ar
e
s
w
i
n
g
s
b
et
w
ee
n
t
h
e
4
7
to
5
3
H
z
s
o
th
e
in
ter
f
er
en
ce
al
s
o
ef
f
ec
t
s
f
r
o
m
t
h
i
s
r
an
g
e
o
f
p
o
w
er
lin
e
s
i
g
n
al.
T
o
m
i
tig
a
te
th
is
d
y
n
a
m
ic
in
ter
f
er
en
ce
f
r
o
m
p
o
w
er
li
n
e
w
e
n
ee
d
u
s
e
ad
ap
tiv
e
f
ilter
to
s
u
p
p
r
ess
th
i
s
r
an
d
o
m
n
o
i
s
e
ca
u
s
i
n
g
f
r
o
m
p
o
w
er
li
n
e
[
3
]
.
An
ad
ap
tiv
e
n
o
is
e
eli
m
i
n
atio
n
f
ilter
h
a
s
b
ee
n
u
s
ed
to
ev
ad
e
t
h
i
s
i
m
p
en
d
i
n
g
l
o
s
s
o
f
i
n
f
o
r
m
atio
n
.
Fo
u
r
d
i
f
f
er
en
t
w
a
v
es
ca
n
b
e
o
b
s
er
v
ed
w
h
ile
r
ec
o
r
d
in
g
E
C
G
s
ig
n
al
t
h
o
s
e
ar
e
P
QR
ST
.
T
h
e
d
ep
o
lar
izatio
n
o
f
r
ig
h
t
atr
i
a
r
ep
r
esen
ts
P
w
av
e.
W
h
ile
t
h
e
r
ap
id
d
ep
o
lar
izatio
n
o
f
r
i
g
h
t
an
d
le
f
t
v
e
n
tr
icles
r
ep
r
esen
ts
Q
R
S
w
a
v
e.
T
h
e
r
ep
o
lar
izatio
n
o
f
th
e
v
en
tr
ic
les
r
ep
r
ese
n
ts
T
w
a
v
e
[
4
]
,
[
5
]
.
An
y
d
ev
iat
io
n
i
n
th
e
s
aid
p
ar
a
m
eter
s
l
ea
d
s
ab
n
o
r
m
alities
in
th
e
h
ea
r
t
.
T
h
e
w
av
e
f
o
r
m
r
elate
d
to
QR
S
co
m
p
lex
r
ep
r
esen
t
t
h
e
co
n
tr
ac
tio
n
o
f
le
f
t
an
d
r
ig
h
t
v
e
n
tr
ic
les,
w
h
ic
h
is
m
o
r
e
p
o
w
er
f
u
l
t
h
an
t
h
at
o
f
at
r
ia
.
I
t
co
m
p
r
is
es
m
u
s
cle
m
as
s
an
d
ca
u
s
in
g
a
m
o
r
e
E
C
G
d
ef
le
ctio
n
.
T
h
e
Q
w
a
v
e
s
ig
n
i
f
ies
t
h
e
s
ig
n
al
h
o
r
izo
n
ta
l
(
i.e
.
lef
t
to
r
ig
h
t)
cu
r
r
en
t
a
s
a
p
o
ten
tial
tr
av
e
l
th
r
o
u
g
h
t
h
e
in
ter
-
v
en
tr
icu
lar
s
y
s
te
m
.
T
h
e
Q
w
av
e
i
s
n
o
t
h
a
v
in
g
a
s
ep
tal
o
r
ig
in
s
h
o
w
s
m
y
o
ca
r
d
ial
v
i
o
latio
n
w
h
ich
i
n
v
o
l
v
es
th
e
f
u
ll
d
ep
th
o
f
Evaluation Warning : The document was created with Spire.PDF for Python.
I
n
t J
E
lec
&
C
o
m
p
E
n
g
I
SS
N:
2
0
8
8
-
8708
N
o
is
e
r
ed
u
ctio
n
in
E
C
G
s
ig
n
a
ls
fo
r
b
io
-
teleme
tr
y
(
V
.
Ja
g
a
n
N
a
ve
en
)
1029
m
y
o
ca
r
d
iu
m
.
T
h
e
P
w
av
e
ar
is
es
w
h
e
n
th
e
S
A
n
o
d
e
(
Sin
u
s
A
tr
ia)
g
e
n
er
ates
a
p
o
ten
tial
wh
ich
d
ep
o
lar
izes
th
e
atr
ia
.
Ho
w
ev
er
as
lo
n
g
a
s
t
h
e
atr
ial
d
ep
o
lar
izatio
n
tak
es
p
lace
to
s
p
r
ea
d
th
r
o
u
g
h
th
e
A
V
n
o
d
e
to
th
e
v
en
tr
ic
le
s
,
ea
c
h
p
w
av
e
s
h
o
u
l
d
b
e
tr
ailed
b
y
QR
S
co
m
p
le
x
[
6
].
Fro
m
th
e
co
m
m
e
n
ce
m
en
t
o
f
Q
R
S
co
m
p
lex
i
s
ca
lled
P
R
in
ter
v
al.
T
h
is
i
n
d
ic
ates
th
e
t
i
m
e
t
h
at
i
t
tak
e
s
f
o
r
th
e
elec
tr
ical
i
m
p
u
l
s
es
p
r
o
d
u
c
ed
in
th
e
S
A
n
o
d
e
an
d
to
tr
av
el
th
r
o
u
g
h
t
h
e
atr
i
a
an
d
ac
r
o
s
s
th
e
A
V
n
o
d
e
(
Atr
ia
Ven
tr
icle)
n
o
d
e
to
th
e
v
e
n
tr
icle.
I
n
ad
ap
ti
v
e
f
ilter
,
leas
t
m
ea
n
s
q
u
ar
e
al
g
o
r
ith
m
r
eq
u
ir
es
i
n
p
u
t
s
i
g
n
a
l
an
d
r
ef
er
en
ce
s
ig
n
al
to
u
p
d
ate
th
e
(
tap
w
ei
g
h
t
s
)
f
ilter
co
ef
f
icie
n
t
s
o
f
t
h
e
ad
ap
tiv
e
FI
R
f
ilter
.
Fo
r
ev
er
y
iter
atio
n
,
L
MS
alg
o
r
it
h
m
u
p
d
ate
n
e
w
tap
w
ei
g
h
ts
b
a
s
ed
o
n
th
e
p
r
ev
io
u
s
tap
w
ei
g
h
ts
to
m
in
i
m
ize
t
h
e
er
r
o
r
.
A
f
ter
s
e
v
er
al
iter
atio
n
s
,
it
eli
m
i
n
ate
t
h
e
n
o
is
e
in
t
h
e
ad
ap
tiv
e
f
ilter
an
d
g
i
v
es
b
est
m
in
i
m
u
m
m
ea
n
s
q
u
ar
e
er
r
o
r
.
T
h
is
m
eth
o
d
f
o
llo
w
s
th
e
co
m
p
u
tatio
n
b
ased
o
n
th
e
p
ast
av
ailab
le
i
n
f
o
r
m
atio
n
.
T
h
e
R
L
S
(
r
ec
u
r
s
iv
e
least
s
q
u
ar
e)
alg
o
r
it
h
m
g
i
v
e
s
b
etter
co
n
v
er
g
en
ce
th
a
n
L
M
S
alg
o
r
ith
m
[
7
]
.
T
h
e
m
ai
n
d
is
ad
v
an
ta
g
e
o
f
t
h
e
R
L
S
al
g
o
r
ith
m
is
h
av
in
g
h
i
g
h
co
m
p
u
ta
tio
n
al
co
s
t
.
I
n
th
e
p
ap
er
,
S
ec
tio
n
2
sh
o
w
s
t
h
e
L
MS
a
n
d
R
L
S
al
g
o
r
ith
m
,
S
ec
tio
n
3
gi
v
es
th
e
s
i
m
u
latio
n
r
es
u
lts
a
n
d
S
ec
tio
n
4
g
iv
e
s
th
e
co
n
clu
s
io
n
r
es
u
lts
.
2.
ADAP
T
I
VE
F
I
L
T
E
R
I
N
G
A
d
ap
tiv
e
f
ilter
i
n
v
o
lv
es
t
h
e
al
ter
atio
n
o
f
f
i
lter
p
ar
a
m
eter
s
(
co
ef
f
icie
n
t)
o
v
er
ti
m
e
to
r
ed
u
ce
th
e
n
o
is
e
in
th
e
s
i
g
n
al
an
d
to
m
in
i
m
ize
th
e
er
r
o
r
[
8
]
.
Dig
ital
s
i
g
n
a
l
p
r
o
ce
s
s
in
g
ex
h
ib
ited
b
y
m
o
s
t
o
f
th
e
ad
ap
tiv
e
f
ilter
s
w
il
l
b
e
d
ig
ital
in
n
atu
r
e
b
ec
au
s
e
o
f
co
m
p
lex
i
t
y
i
n
o
p
ti
m
izi
n
g
alg
o
r
it
h
m
s
.
A
d
ap
tiv
e
f
ilter
s
ar
e
b
est
s
u
ited
w
h
e
n
th
er
e
is
lar
g
e
u
n
ce
r
tain
t
y
a
n
d
f
ilter
h
a
s
to
co
m
p
en
s
ate
t
h
at
o
r
s
ig
n
al
co
n
d
it
io
n
s
ar
e
s
lo
w
l
y
c
h
an
g
i
n
g
.
T
h
e
p
er
f
o
r
m
a
n
ce
o
f
ad
ap
ti
v
e
f
ilte
r
in
v
o
lv
e
s
t
w
o
p
r
o
ce
ss
,
w
h
ic
h
ar
e
f
ilter
p
r
o
ce
s
s
i
n
g
a
n
d
ad
a
p
tatio
n
p
r
o
ce
s
s
[
9
]
.
T
h
e
ad
ap
tiv
e
f
ilter
o
u
tp
u
t
Z
(
n
)
is
g
i
v
en
a
s
:
Z
(
n
)
=P
(
n
)
S(n
)
(1
)
w
h
er
e
S(n
)
is
t
h
e
i
n
p
u
t E
C
G
s
i
g
n
al
a
n
d
P
(
n
)
ar
e
th
e
ad
ap
tiv
e
f
ilter
co
ef
f
icie
n
ts
.
As
w
e
k
n
o
w
n
E
C
G
s
i
g
n
al
in
t
er
f
er
en
ce
b
y
5
0
Hz
p
o
w
er
lin
e
s
ig
n
a
l
.
s
o
,
w
e
h
a
v
e
to
s
u
p
p
r
ess
th
e
5
0
Hz
co
m
p
o
n
en
t
i
n
t
h
e
E
C
G
s
i
g
n
al
w
h
ic
h
ar
e
o
r
ig
in
a
ted
b
y
th
e
p
o
w
er
li
n
e.
I
f
w
e
r
e
m
o
v
e
co
m
p
lete
5
0
Hz
co
m
p
o
n
e
n
t
i
n
t
h
e
E
C
G
s
i
g
n
a
l
th
er
e
m
a
y
b
e
d
ata
lo
s
s
i
n
t
h
e
E
C
G
s
ig
n
al
w
h
ic
h
ar
e
ass
o
ciate
d
w
it
h
5
0
Hz
f
r
eq
u
en
c
ies
r
eg
io
n
.
So
w
e
n
ee
d
to
esti
m
ate
th
e
d
is
tu
r
b
an
ce
b
y
p
o
w
er
lin
e
s
ig
n
al
f
o
r
th
at
we
g
iv
i
n
g
p
o
w
er
li
n
e
s
ig
n
al
a
s
r
ef
er
en
ce
to
th
e
ad
ap
tiv
e
f
ilter
.
No
w
t
h
e
ad
ap
tiv
e
f
i
lter
w
i
ll tr
ac
k
t
h
e
p
o
w
er
lin
e
c
o
m
p
o
n
en
t
s
i
n
E
C
G
s
ig
n
al
a
n
d
w
e
ca
n
ea
s
il
y
e
x
tr
a
ct
in
ter
f
er
en
ce
p
ar
t in
t
h
e
E
C
G
s
i
g
n
a
l
.
T
h
e
d
if
f
er
en
ce
b
et
w
e
en
t
h
e
d
esire
d
s
ig
n
a
l
d
(
n
)
an
d
th
e
s
i
g
n
a
l f
r
o
m
t
h
e
o
u
tp
u
t o
f
th
e
f
ilter
Z
(
n
)
is
t
h
e
er
r
o
r
s
ig
n
al
e(
n
)
.
(
)
(
)
(
)
(
2
)
T
h
e
f
ilter
v
ar
iab
le
u
p
d
ates
f
ilt
er
co
ef
f
icie
n
ts
at
e
v
er
y
ti
m
e
i
n
s
tan
ta
n
eo
u
s
.
(
)
(
)
(
)
(
3
)
W
h
er
e
P
(
n
+1
)
is
th
e
u
p
d
ated
w
ei
g
h
t
v
ec
to
r
w
it
h
th
e
p
r
ev
i
o
u
s
w
eig
h
t
v
ec
to
r
an
d
is
th
e
co
r
r
ec
ti
o
n
f
ac
to
r
d
ep
en
d
s
o
n
th
e
v
a
lu
e.
3.
L
E
A
ST
M
E
AN
S
Q
UAR
E
A
L
G
O
R
I
T
H
M
T
h
ese
alg
o
r
ith
m
s
w
as
s
u
g
g
est
ed
b
y
W
id
r
o
w
a
n
d
Ho
f
f
.
T
h
ey
d
ev
elo
p
ed
L
M
S
f
r
o
m
th
e
ir
s
tu
d
ie
s
o
f
p
atter
n
r
ec
o
g
n
i
tio
n
[
1
0
]
.
I
n
t
h
e
L
MS
al
g
o
r
ith
m
s
,
th
e
co
r
r
ec
tio
n
ap
p
lied
to
th
e
ab
o
v
e
m
en
tio
n
ed
est
i
m
a
te
in
cl
u
d
es
p
r
o
d
u
ct
o
f
th
r
ee
f
ac
t
o
r
s
:
th
e
er
r
o
r
s
ig
n
al
e
(
n
-
1
)
,
t
h
e
(
s
ca
lar
)
s
tep
-
s
ize
p
ar
a
m
ete
r
(
µ)
an
d
th
e
tap
-
in
p
u
t
v
ec
to
r
s
(
n
-
1
)
.
L
MS
al
g
o
r
ith
m
i
s
th
e
b
est
s
e
lectio
n
i
f
we
ar
e
d
ea
lin
g
w
it
h
ad
ap
tiv
e
d
i
g
ital
cir
c
u
it
s
i
n
th
is
ca
s
e
a
f
ilter
th
a
t
r
ej
ec
t
th
e
b
an
d
s
o
f
s
ig
n
al
th
o
s
e
ca
u
s
es
i
n
t
er
f
er
en
ce
to
th
e
E
C
G
[
1
1
]
.
T
h
e
b
asic
o
p
er
atio
n
o
f
L
MS
al
g
o
r
ith
m
i
s
th
e
r
ec
u
r
s
i
v
e
u
p
d
atin
g
n
at
u
r
e
o
f
f
il
ter
co
ef
f
icie
n
ts
b
y
t
h
e
r
ef
er
e
n
ce
o
f
er
r
o
r
s
ig
n
al.
E
ac
h
iter
atio
n
o
f
L
M
S in
v
o
lv
e
s
th
r
ee
s
tep
s
:
Fil
ter
o
u
tp
u
t
:
[
]
∑
[
]
[
]
(
4
)
Evaluation Warning : The document was created with Spire.PDF for Python.
I
SS
N
:
2
0
8
8
-
8708
I
n
t J
E
lec
&
C
o
m
p
E
n
g
,
Vo
l.
9
,
No
.
2
,
A
p
r
il 2
0
1
9
:
1
0
2
8
-
1035
1030
E
s
ti
m
a
tio
n
er
r
o
r
:
(
)
(
)
(
)
(
5
)
T
ap
-
w
eig
h
t a
d
ap
tatio
n
:
[
]
[
]
[
]
[
]
(
6
)
d
(
n
)
is
ta
k
en
as
d
esire
d
s
ig
n
a
l
an
d
Z
(
n
)
i
s
t
h
e
o
u
tp
u
t
r
esp
o
n
s
e
o
f
th
e
ad
ap
tiv
e
f
ilter
eq
u
atio
n
4
s
h
o
w
s
t
h
e
o
u
tp
u
t r
esp
o
n
s
e
o
f
th
e
Fil
ter
with
i
n
p
u
t s
ig
n
al
S(
n
)
an
d
f
il
ter
co
ef
f
icie
n
t
s
P
(
n
)
.
4.
RE
CUR
SI
V
E
L
E
AS
T
S
Q
U
ARE A
L
G
O
R
I
T
H
M
W
ith
s
u
p
r
e
m
e
co
m
p
u
tatio
n
al
co
m
p
le
x
it
y
,
R
L
S
is
th
e
f
a
s
test
co
n
v
er
g
i
n
g
alg
o
r
ith
m
.
I
t
ca
n
ce
ls
m
ax
i
m
u
m
a
m
o
u
n
t
o
f
n
o
is
e
b
y
m
i
n
i
m
izi
n
g
er
r
o
r
w
it
h
th
e
f
aste
s
t
r
ate.
So
in
th
is
s
tu
d
y
,
a
tr
ad
eo
f
f
b
et
w
ee
n
co
m
p
u
tatio
n
al
co
m
p
le
x
it
y
a
n
d
co
n
v
er
g
e
n
ce
r
ate
is
d
o
n
e
t
o
attain
th
e
u
t
m
o
s
t
n
o
is
e
f
r
e
e
s
i
g
n
al.
T
h
e
f
ilter
o
u
tp
u
t a
n
d
er
r
o
r
f
u
n
ctio
n
o
f
R
L
S a
l
g
o
r
ith
m
ar
e
s
h
o
w
n
i
n
E
q
u
atio
n
s
(
8
)
an
d
(
9
)
.
(
)
(
)
(
)
(
)
(
)
(
7
)
W
h
er
e
R
(
n
)
is
th
e
v
ec
to
r
g
ain
,
L
(
n
)
is
t
h
e
in
v
er
s
e
co
r
r
elatio
n
m
atr
i
x
,
u
(
n
)
is
t
h
e
b
u
f
f
er
ed
in
p
u
t
v
ec
to
r
an
d
d
en
o
tes th
e
r
ec
ip
r
o
ca
l o
f
th
e
e
x
p
o
n
en
t
ial
w
ei
g
h
t
i
n
g
f
ac
to
r
.
T
h
e
f
i
lter
o
u
tp
u
t i
s
:
(
)
(
)
(
)
(
8
)
E
r
r
o
r
s
ig
n
al:
(
)
(
)
(
)
(
9
)
T
h
e
u
p
d
ated
co
ef
f
icien
t
s
as s
h
o
w
n
in
eq
u
at
io
n
:
(
)
(
)
(
)
(
)
(
1
0
)
(
)
(
)
(
)
[
(
)
(
)
]
(
1
1)
(
)
(
)
(
)
[
(
)
(
)
(
)
]
(
1
2
)
w
h
er
e
(
)
is
th
e
g
ai
n
co
n
s
ta
n
t,
w
ith
a
s
eq
u
en
ce
o
f
tr
ai
n
i
n
g
d
ata
u
p
to
ti
m
e,
t
h
e
R
L
S
alg
o
r
it
h
m
esti
m
ates
th
e
w
ei
g
h
t
b
y
m
i
n
i
m
izi
n
g
t
h
e
r
esu
lt
in
g
co
s
t
[
1
3
]
.
w
h
er
e
u
(
n
)
is
th
e
i
n
p
u
t,
an
d
λ
is
th
e
s
tab
ilizatio
n
p
ar
am
eter
.
5.
RE
SU
L
T
S
A
ND
AN
AL
Y
SI
S
E
C
G
s
i
g
n
als
ar
e
r
a
n
d
o
m
l
y
tak
en
f
r
o
m
MI
T
_
B
I
H
d
ata
b
ase
i.e
.
(
1
0
1
,
1
0
4
,
1
0
6
,
1
0
9
,
1
2
4
)
[
1
4
]
-
[
1
6
]
.
T
h
e
len
g
th
o
f
ea
ch
E
C
G
s
ig
n
al
is
r
estricte
d
to
3
6
0
0
s
a
m
p
le
s
.
I
n
L
M
S
al
g
o
r
it
h
m
t
h
e
m
u
i
s
ta
k
en
as
0
.
0
2
an
d
i
n
R
L
S
al
g
o
r
ith
m
la
m
b
d
a
is
ta
k
en
as
o
n
e
r
an
d
o
m
l
y
.
Ma
tlab
is
ta
k
en
as
a
to
o
l
f
o
r
s
i
m
u
l
atio
n
s
a
n
d
n
o
i
s
e
is
co
n
s
id
er
ed
as
A
d
ap
tiv
e
W
h
ite
Gau
s
s
ian
No
is
e
(
A
W
GN)
w
it
h
p
o
w
er
li
n
e
i
n
ter
f
er
e
n
ce
o
f
5
0
Hz
o
n
E
C
G
s
i
g
n
al
w
it
h
less
n
o
i
s
e
p
o
w
er
.
Af
ter
d
e
-
n
o
i
s
in
g
u
s
in
g
L
M
S
a
n
d
R
L
S
alg
o
r
it
h
m
,
E
C
G
s
i
g
n
als
p
e
ak
s
ar
e
e
s
ti
m
ated
a
n
d
r
esu
lt
s
ar
e
co
m
p
ar
ed
w
it
h
o
r
ig
in
al
s
i
g
n
als
w
i
th
o
u
t n
o
i
s
e.
3
.
1
I
m
p
le
m
e
n
tatio
n
o
f
L
M
S
A
l
g
o
r
ith
m
b
y
r
ed
u
cin
g
c
h
an
n
el
No
is
e
a
n
d
r
ed
u
cin
g
P
o
w
er
li
n
e
in
ter
f
er
e
n
ce
o
f
5
0
Hz
in
E
C
G
Sig
n
al
S
h
o
w
n
i
n
Fi
g
u
r
e
1
to
Fig
u
r
e
7
an
d
T
ab
le
1
to
Fig
u
r
e
10
.
Evaluation Warning : The document was created with Spire.PDF for Python.
I
n
t J
E
lec
&
C
o
m
p
E
n
g
I
SS
N:
2
0
8
8
-
8708
N
o
is
e
r
ed
u
ctio
n
in
E
C
G
s
ig
n
a
ls
fo
r
b
io
-
teleme
tr
y
(
V
.
Ja
g
a
n
N
a
ve
en
)
1031
Fig
u
r
e
1
.
E
C
G
w
a
v
e
f
o
r
m
f
r
o
m
MI
T
-
B
I
H
d
atab
ase
Fig
u
r
e
2
.
No
is
e
s
ig
n
al
Fig
u
r
e
3
.
E
C
G
s
i
g
n
al
+
n
o
is
e
Evaluation Warning : The document was created with Spire.PDF for Python.
I
SS
N
:
2
0
8
8
-
8708
I
n
t J
E
lec
&
C
o
m
p
E
n
g
,
Vo
l.
9
,
No
.
2
,
A
p
r
il 2
0
1
9
:
1
0
2
8
-
1035
1032
Fig
u
r
e
4
.
No
is
e
r
e
m
o
v
al
i
n
E
C
G
Sig
n
al
u
s
i
n
g
L
M
S a
lg
o
r
it
h
m
Fig
u
r
e
5
.
(
5
0
Hz)
P
o
w
er
L
i
n
e
I
n
ter
f
er
e
n
ce
s
u
p
p
r
ess
io
n
u
s
i
n
g
L
MS
Alg
o
r
it
h
m
Fig
u
r
e
6
.
No
is
e
r
e
m
o
v
al
i
n
E
C
G
Sig
n
al
u
s
i
n
g
L
M
S a
lg
o
r
it
h
m
Evaluation Warning : The document was created with Spire.PDF for Python.
I
n
t J
E
lec
&
C
o
m
p
E
n
g
I
SS
N:
2
0
8
8
-
8708
N
o
is
e
r
ed
u
ctio
n
in
E
C
G
s
ig
n
a
ls
fo
r
b
io
-
teleme
tr
y
(
V
.
Ja
g
a
n
N
a
ve
en
)
1033
Fig
u
r
e
7
.
(
5
0
Hz)
P
o
w
er
L
i
n
e
I
n
ter
f
er
e
n
ce
s
u
p
p
r
ess
io
n
u
s
i
n
g
R
L
S
A
l
g
o
r
ith
m
T
ab
le
1
.
C
h
an
n
e
l n
o
is
e
r
ed
u
ct
i
o
n
o
n
E
C
G
s
i
g
n
al
u
s
i
n
g
L
M
S a
lg
o
r
ith
m
b
y
co
n
s
id
er
in
g
i
n
ter
f
er
en
ce
o
f
t
h
e
s
a
m
e
s
ig
n
al
by
it
h
d
i
f
f
er
e
n
t p
h
ase
in
t
h
e
ch
a
n
n
el
w
it
h
m
u
=0
.
0
2
tak
en
r
an
d
o
m
l
y
S
i
g
n
a
l
s fr
o
m M
I
T
_
B
I
H
d
a
t
a
b
a
se
EC
G
S
i
g
n
a
l
P
o
w
e
r
(
d
B
)
N
o
i
se
S
i
g
n
a
l
P
o
w
e
r
(
d
B
)
P
o
w
e
r
o
f
t
h
e
Er
r
o
r
S
i
g
n
a
l
(
d
B
)
M
e
a
n
S
q
u
a
r
e
d
e
v
i
a
t
i
o
n
(
d
B
)
1
0
1
-
0
.
3
3
3
9
0
.
0
8
4
3
-
8
.
9
6
2
0
-
2
1
.
2
7
2
6
1
0
4
-
0
.
1
9
5
4
0
.
1
0
3
4
-
8
.
7
9
4
3
-
2
1
.
0
2
8
7
1
0
6
-
0
.
0
9
2
2
0
.
0
7
0
2
-
8
.
6
9
6
7
-
2
1
.
0
2
4
3
1
0
9
-
0
.
4
8
6
6
0
.
0
7
7
1
-
9
.
1
0
0
9
-
2
1
.
0
8
9
1
1
2
4
-
1
.
2
1
4
8
-
0
.
0
3
2
-
9
.
8
2
9
7
-
2
2
.
5
2
2
0
T
ab
le
2
.
P
o
w
er
li
n
e
in
ter
f
er
en
ce
o
f
5
0
Hz
o
n
E
C
G
s
ig
n
al
b
y
r
ed
u
cin
g
in
ter
f
er
en
ce
u
s
i
n
g
L
MS
alg
o
r
it
h
m
b
y
co
n
s
id
er
in
g
in
ter
f
er
e
n
ce
o
f
th
e
s
a
m
e
s
i
g
n
al
b
y
t
h
e
d
if
f
er
en
t p
h
ase
i
n
th
e
c
h
a
n
n
el
Ty
p
e
s o
f
S
i
g
n
a
l
f
r
o
m
M
I
T
_
B
I
H
d
a
t
a
b
a
se
EC
G
si
g
n
a
l
P
o
w
e
r
(
d
B
)
N
o
i
se
si
g
n
a
l
P
o
w
e
r
(
d
B
)
P
o
w
e
r
o
f
t
h
e
S
i
g
n
a
l
a
n
d
N
o
i
se
(
d
B
)
P
o
w
e
r
o
f
t
h
e
Er
r
o
r
S
i
g
n
a
l
(
d
B
)
M
e
a
n
S
q
u
a
r
e
d
e
v
i
a
t
i
o
n
(
d
B
)
1
0
1
-
0
.
3
3
3
9
-
3
.
0
1
0
5
.
6
8
2
0
-
2
.
9
1
5
8
-
2
9
.
0
4
4
1
0
4
-
0
.
1
9
5
4
-
3
.
0
1
0
5
.
8
2
0
6
-
2
.
7
7
3
7
-
2
8
.
8
0
4
1
1
0
6
-
0
.
0
9
2
2
-
3
.
0
1
0
5
.
9
2
1
8
-
2
.
6
6
8
0
-
2
8
.
7
9
7
6
1
0
9
-
0
.
4
8
6
6
-
3
.
0
1
0
5
.
5
2
6
7
-
3
.
0
6
2
7
-
2
8
.
8
6
3
9
1
2
4
-
1
.
2
1
4
8
-
3
.
0
1
0
4
.
8
0
0
1
-
3
.
7
8
8
2
-
3
0
.
2
9
6
5
T
ab
le
3
.
C
h
an
n
e
l n
o
is
e
r
ed
u
ct
i
o
n
o
n
E
C
G
s
i
g
n
al
u
s
i
n
g
R
L
S
alg
o
r
ith
m
b
y
co
n
s
id
er
in
g
i
n
ter
f
er
en
ce
o
f
t
h
e
s
a
m
e
s
ig
n
al
b
y
it
h
d
i
f
f
er
e
n
t p
h
ase
in
t
h
e
ch
a
n
n
el
w
it
h
=1
tak
en
r
an
d
o
m
l
y
S
i
g
n
a
l
s fr
o
m M
I
T
-
B
I
H
A
r
r
h
y
t
h
mi
a
d
a
t
a
b
a
se
EC
G
si
g
n
a
l
P
o
w
e
r
(
d
B
)
N
o
i
se
si
g
n
a
l
P
o
w
e
r
(
d
B
)
P
o
w
e
r
o
f
t
h
e
e
r
r
o
r
S
i
g
n
a
l
(
d
B
)
1
0
1
-
0
.
3
3
3
9
-
0
.
0
4
6
7
-
0
.
0
2
7
4
1
0
4
-
0
.
1
9
5
4
-
0
.
0
4
7
2
-
0
.
0
5
8
1
1
0
6
-
0
.
0
9
2
2
-
0
.
1
8
5
4
-
0
.
0
6
3
0
1
0
9
0
.
4
8
6
6
-
0
.
2
2
6
4
0
.
0
2
6
8
1
2
4
-
1
.
2
1
4
8
-
0
.
0
4
9
4
0
.
0
0
6
5
T
ab
le
4
.
P
o
w
er
li
n
e
in
ter
f
er
en
ce
o
f
5
0
Hz
o
n
E
C
G
s
ig
n
al
b
y
r
ed
u
cin
g
in
ter
f
er
en
ce
u
s
i
n
g
R
L
S a
l
g
o
r
ith
m
b
y
co
n
s
id
er
in
g
in
ter
f
er
e
n
ce
o
f
th
e
s
a
m
e
s
i
g
n
al
b
y
t
h
e
d
if
f
er
en
t p
h
ase
i
n
th
e
c
h
a
n
n
el
S
i
g
n
a
l
f
r
o
m M
I
T
-
B
I
H
d
a
t
a
b
a
se
P
o
w
e
r
o
f
t
h
e
o
r
i
g
i
n
a
l
EC
G
si
g
n
a
l
(
d
B
)
N
o
i
se
si
g
n
a
l
P
o
w
e
r
(
d
B
)
P
o
w
e
r
o
f
t
h
e
S
i
g
n
a
l
a
n
d
N
o
i
se
(
d
B
)
P
o
w
e
r
o
f
t
h
e
Er
r
o
r
S
i
g
n
a
l
(
d
B
)
1
0
1
-
0
.
3
3
3
9
-
3
.
0
1
0
3
5
.
6
8
7
9
-
0
.
0
2
7
4
1
0
4
-
0
.
1
9
5
4
-
3
.
0
1
0
3
5
.
8
2
7
4
-
0
.
0
5
8
1
1
0
6
-
0
.
0
9
2
2
-
3
.
0
1
0
3
5
.
9
3
2
0
-
0
.
0
6
3
0
1
0
9
-
0
.
4
8
6
6
-
3
.
0
1
0
3
5
.
5
3
6
0
0
.
0
2
6
8
1
2
4
-
1
.
2
1
4
8
-
3
.
0
1
0
3
4
.
8
1
1
4
0
.
0
0
6
5
T
ab
le
5
.
E
s
tim
a
tio
n
s
i
g
n
al
p
o
w
er
i
n
ti
m
e
an
d
f
r
eq
u
e
n
c
y
d
o
m
ai
n
f
o
r
th
e
S
ig
n
al
s
f
r
o
m
MI
T
-
B
I
H
Evaluation Warning : The document was created with Spire.PDF for Python.
I
SS
N
:
2
0
8
8
-
8708
I
n
t J
E
lec
&
C
o
m
p
E
n
g
,
Vo
l.
9
,
No
.
2
,
A
p
r
il 2
0
1
9
:
1
0
2
8
-
1035
1034
S
i
g
n
a
l
s fr
o
m M
I
T
-
B
I
H
A
r
r
h
y
t
h
mi
a
d
a
t
a
b
a
se
P
o
w
e
r
T
i
me
d
o
mai
n
(
d
B
)
P
o
w
e
r
F
r
e
q
u
e
n
c
y
d
o
mai
n
(
d
B
)
1
0
1
-
0
.
3
3
2
7
-
0
.
3
9
3
8
1
0
4
-
0
.
1
9
3
2
-
0
.
1
9
2
0
1
0
6
-
0
.
0
8
8
6
-
0
.
0
8
0
1
1
0
9
-
0
.
4
8
4
5
-
0
.
5
6
3
5
1
2
4
-
1
.
2
0
9
2
-
0
.
9
7
3
3
T
ab
le
6
.
E
ac
h
E
C
G
s
ig
n
al
’
s
le
n
g
t
h
i
s
h
a
v
i
n
g
3
6
0
0
s
a
m
p
les
u
n
d
er
n
o
is
e
les
s
co
n
d
itio
n
s
,
QR
ST
p
ea
k
s
ar
e
esti
m
ated
in
E
C
G
s
i
g
n
al
s
as s
h
o
w
n
i
n
t
h
e
tab
le
(
m
V)
S
i
g
n
a
l
f
r
o
m
M
I
T
-
B
I
H
d
a
t
a
b
a
se
R
P
e
a
k
(
mV
)
S
P
e
a
k
(
mV
)
T
P
e
a
k
(
mV
)
Q
P
e
a
k
(
mV
)
H
e
a
r
t
R
a
t
e
b
e
a
t
s/
mi
n
1
0
1
2
0
3
.
2
3
-
2
5
.
5
3
5
3
5
.
9
6
5
-
6
.
6
7
2
4
5
.
8
3
1
0
4
2
6
6
.
1
2
3
.
4
5
8
2
5
9
.
4
7
1
4
1
.
6
1
6
5
8
.
3
3
1
0
6
3
5
5
.
2
4
-
2
6
.
9
0
2
1
4
5
.
8
0
3
1
1
5
.
9
2
5
4
.
1
6
1
0
9
2
5
6
.
3
7
2
2
3
.
8
3
2
2
0
8
.
2
4
1
6
3
.
6
1
1
6
6
.
6
6
1
2
4
3
9
0
.
5
9
-
4
1
.
2
4
5
2
0
.
3
1
0
3
1
0
2
.
8
3
3
.
3
3
T
ab
le
7
.
L
MS
alg
o
r
ith
m
i
s
tak
en
o
n
n
o
i
s
y
E
C
G
s
i
g
n
als
w
h
ic
h
ar
e
co
r
r
u
p
ted
w
ith
ad
d
iti
v
e
w
h
ite
g
au
s
s
ia
n
n
o
is
e.
QR
ST
p
ea
k
s
ar
e
m
ea
s
u
r
ed
(
m
V)
S
i
g
n
a
l
s fr
o
m M
I
T
-
B
I
H
d
a
t
a
b
a
se
R
P
e
a
k
(
mV
)
S
P
e
a
k
(
mV
)
T
P
e
a
k
(
mV
)
Q
P
e
a
k
(
mV
)
H
e
a
r
t
R
a
t
e
b
e
a
t
s/
mi
n
1
0
1
7
5
.
6
5
-
9
.
4
6
9
1
3
.
2
0
0
-
2
.
7
0
6
4
5
.
8
3
1
0
4
9
8
.
9
9
1
.
3
1
7
9
6
.
5
0
3
5
2
.
6
7
1
5
8
.
3
3
1
0
6
1
3
2
.
3
6
-
9
.
6
9
0
5
4
.
3
0
9
4
2
.
8
7
5
4
.
1
6
1
0
9
9
4
.
7
1
8
.
8
6
7
7
.
4
3
6
6
0
.
4
9
6
6
.
6
6
1
2
4
1
4
5
.
1
5
-
1
5
.
4
2
7
.
3
9
8
3
8
.
2
3
3
3
3
.
3
3
T
ab
le
8
.
L
MS
alg
o
r
ith
m
i
s
in
tr
o
d
u
ce
d
o
n
s
ig
n
al
o
f
E
C
G
to
m
in
i
m
ize
t
h
e
5
0
Hz
p
o
w
er
li
n
e
i
n
ter
f
er
e
n
ce
o
n
E
C
G
s
y
s
te
m
f
o
r
co
n
s
id
er
in
g
m
u
=0
.
0
2
.
T
h
e
r
ea
d
in
g
s
ar
e
tak
en
in
ter
m
s
o
f
m
i
lli v
o
lt
s
as s
h
o
w
n
in
t
h
e
tab
le
S
i
g
n
a
l
f
r
o
m M
I
T
-
B
I
H
A
r
r
h
y
t
h
mi
a
d
a
t
a
b
a
se
R
P
e
a
k
(
mV
)
S
P
e
a
k
(
mV
)
T
P
e
a
k
(
mV
)
Q
P
e
a
k
(
mV
)
H
e
a
r
t
R
a
t
e
b
e
a
t
s/
mi
n
1
0
1
7
5
.
7
4
5
-
9
.
5
7
1
1
3
.
2
4
2
-
2
.
3
9
2
4
5
.
8
3
1
0
4
9
8
.
8
5
5
1
.
6
9
1
9
6
.
3
4
3
5
2
.
5
0
3
5
8
.
3
3
1
0
6
1
3
2
.
2
8
8
-
9
.
8
2
7
5
4
.
3
9
5
4
2
.
8
2
2
5
4
.
1
6
1
0
9
9
6
.
2
6
4
8
.
8
1
3
7
7
.
5
1
1
6
1
.
3
9
6
6
6
.
6
6
1
2
4
1
4
4
.
9
9
4
-
1
5
.
2
0
7
7
.
5
8
4
3
8
.
1
3
7
3
3
.
3
3
T
ab
le
9
.
R
L
S a
lg
o
r
it
h
m
is
ta
k
en
o
n
n
o
i
s
y
E
C
G
s
i
g
n
als to
r
ed
u
ce
A
W
GN
n
o
is
e
o
n
t
h
e
n
o
i
s
y
E
C
G
s
ig
n
al
s
.
R
ea
d
in
g
s
ar
e
tak
e
n
f
o
r
d
if
f
er
e
n
t
s
i
g
n
als i
n
MI
T
d
ata
b
ase
an
d
m
ea
s
u
r
e
m
e
n
ts
ar
e
in
m
il
li v
o
lts
S
i
g
n
a
l
f
r
o
m M
I
T
-
B
I
H
A
r
r
h
y
t
h
mi
a
d
a
t
a
b
a
se
R
P
e
a
k
(
mV
)
S
P
e
a
k
(
mV
)
T
P
e
a
k
(
mV
)
Q
P
e
a
k
(
mV
)
H
e
a
r
t
R
a
t
e
b
e
a
t
s/
mi
n
1
0
1
0
.
2
0
8
-
0
.
0
2
7
0
.
0
3
6
-
0
.
0
0
3
4
5
.
8
3
1
0
4
0
.
2
6
6
0
.
0
0
3
0
.
2
7
0
0
.
1
4
0
5
8
.
3
3
1
0
6
0
.
3
4
1
-
0
.
0
2
9
0
.
1
4
4
0
.
1
1
2
5
4
.
1
6
1
0
9
0
.
2
6
1
0
.
0
2
7
0
.
2
1
4
0
.
1
6
1
6
6
.
6
6
1
2
4
0
.
4
4
6
-
0
.
0
4
7
0
.
0
2
4
0
.
1
1
5
3
3
.
3
3
T
ab
le
1
0
.
R
L
S a
lg
o
r
ith
m
i
s
co
n
s
id
er
ed
to
r
em
o
v
e
p
o
w
er
li
n
e
in
ter
f
er
e
n
ce
o
n
t
h
e
E
C
G
s
i
g
n
als
w
h
ic
h
ar
e
in
ter
f
er
ed
w
it
h
5
0
Hz
p
o
w
er
lin
e
f
r
eq
u
e
n
c
y
in
t
h
e
s
y
s
te
m
.
v
o
lts
S
i
g
n
a
l
f
r
o
m M
I
T
-
B
I
H
A
r
r
h
y
t
h
mi
a
d
a
t
a
b
a
se
R
P
e
a
k
(
mV
)
S
P
e
a
k
(
mV
)
T
P
e
a
k
(
mV
)
Q
P
e
a
k
(
mV
)
H
e
a
r
t
R
a
t
e
b
e
a
t
s/
mi
n
1
0
1
0
.
2
0
8
9
-
0
.
0
2
7
5
0
.
0
3
7
1
-
0
.
0
0
3
5
4
5
.
8
3
1
0
4
0
.
2
6
6
0
0
.
0
0
3
2
0
.
2
7
0
2
0
.
1
4
0
6
5
8
.
3
3
1
0
6
0
.
3
4
1
2
-
0
.
0
2
9
9
0
.
1
4
4
7
0
.
1
0
5
6
5
4
.
1
6
1
0
9
0
.
2
6
2
3
0
.
0
2
7
2
0
.
2
1
4
2
0
.
1
6
1
1
6
6
.
6
6
1
2
4
0
.
4
4
5
9
-
0
.
0
4
7
2
0
.
0
2
4
6
0
.
1
1
5
4
3
3
.
3
3
B
y
o
b
s
er
v
i
n
g
T
ab
le
6
t
o
T
ab
le
1
0
p
o
w
er
lin
e
i
n
ter
f
er
e
n
ce
(
5
0
Hz)
in
th
e
s
y
s
te
m
a
n
d
n
o
is
e
i
n
th
e
ch
an
n
el
ar
e
s
u
p
p
r
ess
ed
to
m
ax
i
m
u
m
e
x
te
n
d
u
s
in
g
L
MS
a
n
d
R
L
S a
lg
o
r
it
h
m
.
T
h
e
p
ea
k
s
o
f
QR
ST
in
E
C
G
w
a
v
es
a
n
d
h
ea
r
t r
ates a
r
e
m
ea
s
u
r
ed
f
o
r
d
if
f
er
en
t
s
ig
n
al
s
f
r
o
m
MI
T
_
B
I
H
d
ata
b
ase.
Evaluation Warning : The document was created with Spire.PDF for Python.
I
n
t J
E
lec
&
C
o
m
p
E
n
g
I
SS
N:
2
0
8
8
-
8708
N
o
is
e
r
ed
u
ctio
n
in
E
C
G
s
ig
n
a
ls
fo
r
b
io
-
teleme
tr
y
(
V
.
Ja
g
a
n
N
a
ve
en
)
1035
6.
CO
NCLU
SI
O
N
I
n
th
is
p
ap
er
,
th
e
E
C
G
s
i
g
n
al
s
ar
e
ta
k
e
n
f
r
o
m
p
h
y
s
i
o
-
n
et
f
o
r
a
n
al
y
s
is
.
Fo
r
B
io
-
tele
m
etr
y
ap
p
licatio
n
s
,
s
ig
n
al
s
ar
e
tr
a
n
s
m
itted
f
r
o
m
r
e
m
o
te
lo
ca
ti
o
n
s
,
L
MS
a
n
d
R
L
S
ad
ap
ti
v
e
alg
o
r
ith
m
s
ar
e
co
n
s
id
er
ed
f
o
r
s
u
p
p
r
ess
io
n
o
f
A
W
GN
n
o
i
s
e
an
d
p
o
w
er
li
n
e
in
ter
f
er
en
ce
o
n
E
C
G
s
i
g
n
al
s
.
T
h
e
an
al
y
s
i
s
i
s
ca
r
r
ied
o
u
t
to
ev
alu
ate
th
e
E
C
G
s
ig
n
al
p
o
w
er
,
n
o
is
e
s
i
g
n
al
an
d
Me
an
s
q
u
ar
e
er
r
o
r
.
I
t
is
o
b
s
er
v
ed
th
at
Me
an
s
q
u
ar
e
er
r
o
r
is
less
in
R
L
S
th
en
L
MS.
No
is
e
ca
n
ce
llatio
n
ca
p
ac
it
y
is
g
o
o
d
in
R
L
S
t
h
an
L
MS.
B
u
t
th
e
i
m
p
le
m
en
ta
tio
n
i
s
co
m
p
le
x
o
v
er
L
MS.
Af
ter
d
en
o
is
i
n
g
at
t
h
e
r
ec
eiv
er
e
n
d
,
QR
ST
p
ea
k
s
an
d
h
ea
r
t
b
ea
t
s
ar
e
esti
m
ated
an
d
co
m
p
ar
ed
w
it
h
t
h
e
o
r
ig
i
n
al
QR
ST
p
ea
k
s
an
d
h
ea
r
t b
ea
ts
.
RE
F
E
R
E
NC
E
S
[1
]
Ja
n
A
d
a
m
e
c
,
Ri
c
h
a
rd
A
d
a
m
e
c
,
L
u
k
a
s
K
a
p
p
e
n
b
e
rg
e
r
a
n
d
P
h
il
ip
p
e
Co
u
m
e
l,
“
ECG
Ho
lt
e
r:
Gu
id
e
to
El
e
c
tro
c
a
rd
io
g
ra
p
h
ic
In
ter
p
re
ta
ti
o
n
”
,
2
0
0
8
e
d
it
i
o
n
,
sp
r
in
g
e
r
sc
ien
c
e
+
b
u
sin
e
ss
m
e
d
ia,
LL
C,
Ne
w
Yo
rk
,
IS
BN
-
9
7
8
-
0
-
3
8
7
-
7
8
1
8
6
-
0
.
Iss
n
(
P
rin
t):
2
2
3
1
–
5
2
8
4
,
V
o
l
-
2
,
Iss
-
1
,
(
2
0
1
2
).
[2
]
Y.
De
r
L
in
a
n
d
Y.
He
n
Hu
,
“
P
o
w
e
r
-
L
in
e
In
terfe
re
n
c
e
D
e
tec
ti
o
n
a
n
d
S
u
p
p
re
ss
io
n
in
ECG
S
ig
n
a
l
P
r
o
c
e
ss
in
g
,
”
IEE
E
T
ra
n
s.
Bi
o
me
d
.
En
g
.
,
V
o
l
.
55
,
P
p
.
3
5
4
-
3
5
7
,
Ja
n
.
(
2
0
0
8
)
.
[3
]
S
u
sh
a
n
ta
M
a
h
a
n
ty
,
“
Co
n
tro
l
a
n
d
Esti
m
a
ti
o
n
o
f
Bio
lo
g
ica
l
S
ig
n
a
l
s
(ECG
)
Us
in
g
A
d
a
p
ti
v
e
S
y
ste
m
,
”
In
ter
n
a
ti
o
n
a
l
J
o
u
rn
a
l
o
f
El
e
c
trica
l
a
n
d
El
e
c
tro
n
ics
En
g
in
e
e
rin
g
(
IJ
EE
E).
[4
]
C.
L
i
a
n
d
C.
Zh
e
n
g
,
“
QRS
De
tec
ti
o
n
b
y
W
a
v
e
let
T
ra
n
s
f
o
r
m
”
,
in
Pro
c
e
e
d
in
g
s
o
f
An
n
u
a
l
In
ter
n
a
ti
o
n
a
l
Co
n
fer
e
n
c
e
o
n
IE
E
E
n
g
.
in
M
e
d
.
&
Bi
o
l.
S
o
c
.
,
S
a
n
Die
g
o
,
Ca
li
f
o
rn
ia,(
1
9
9
3
).
[5
]
Ra
v
i
Ku
m
a
r
J
a
to
th
,
S
a
lad
i
S
.
V
.
K.K.
A
n
o
o
p
a
n
d
Ch
.
M
id
h
u
n
P
ra
b
h
u
,
“
Bio
lo
g
ica
ll
y
In
sp
ired
Ev
o
lu
t
io
n
a
ry
Co
m
p
u
ti
n
g
to
o
ls
f
o
r
th
e
Ex
trac
ti
o
n
o
f
F
e
tal
El
e
c
tro
c
a
rd
io
g
ra
m
”,
W
S
EA
S
T
ra
n
sa
c
ti
o
n
s
o
n
S
ig
n
a
l
Pro
c
e
ss
in
g
,
5
,
No
.
3
,
p
p
.
1
0
6
-
1
1
5
,
M
a
rc
h
(
2
0
0
9
)
.
[6
]
L
o
m
e
D.O,
L
e
a
rn
th
e
He
a
rt,
Co
m
p
lete
Ca
rd
io
lo
g
y
in
a
He
a
rtb
e
a
t,
(2
0
0
3
),
o
n
li
n
e
so
u
c
e
a
v
a
li
a
b
le
a
t:
h
tt
p
:/
/www.
lea
rn
th
e
h
e
a
rt.co
m.
[7
]
K.
M
u
h
sin
;
“
Co
m
p
a
riso
n
o
f
th
e
RL
S
a
n
d
L
M
S
A
lg
o
rit
h
m
s
to
Re
m
o
v
e
P
o
w
e
r
L
in
e
In
terf
e
re
n
c
e
N
o
ise
f
ro
m
EC
G
S
ig
n
a
l
,
”
Al
-
Kh
w
a
rizm
i
E
n
g
i
n
e
e
rin
g
J
o
u
rn
a
l
,
Vo
l.
6
,
N
o
.
2
,
P
P
5
1
-
6
1
(
2
0
1
0
)
.
[8
]
V
.
Ja
g
a
n
Na
v
e
e
n
,
J.
V
e
n
k
a
ta
S
u
m
a
n
a
n
d
P
.
De
v
i
P
ra
d
e
e
p
“
No
is
e
su
p
p
re
ss
io
n
in
sp
e
e
c
h
sig
n
a
ls
u
sin
g
a
d
a
p
ti
v
e
f
il
ter,”
In
ter
n
a
ti
o
n
a
l
jo
u
rn
a
l
o
f
s
ig
n
a
l
p
ro
c
e
ss
in
g
,
ima
g
e
s
p
ro
c
e
ss
in
g
a
n
d
p
a
tt
e
rn
re
c
o
g
n
it
io
n
,
v
o
lu
m
e
3
iss
u
e
3
p
a
g
e
n
o
:
8
7
.
9
6
,
p
u
b
li
s
h
e
d
b
y
S
ERS
C
S
o
u
th
Ko
re
a
.
[9
]
S
im
o
n
Ha
y
k
in
,
“
A
d
a
p
ti
v
e
F
il
ter T
h
e
o
r
y
,
”
F
o
u
rt
h
E
d
it
io
n
,
P
re
n
ti
c
e
Ha
ll
,
In
c
(
2
0
0
2
).
[1
0
]
W
.
Ke
n
n
e
th
Je
n
k
in
s,
A
n
d
re
w
W
.
Hu
ll
,
Je
ff
re
y
C.
S
trait,
Be
rn
a
rd
A
.
S
c
h
n
a
u
f
e
r,
X
iao
h
u
iL
i
,
“
A
d
v
a
n
c
e
d
Co
n
c
e
p
t
i
n
A
d
a
p
ti
v
e
S
ig
n
a
l
P
r
o
c
e
ss
in
g
,
”
Klu
w
e
r
Ac
a
d
e
m
ic P
u
b
l
ish
e
r
(1
9
9
6
).
[1
1
]
N.
Ka
lo
u
p
tsid
is
,
“
A
d
a
p
ti
v
e
S
y
ste
m
Id
e
n
ti
f
ica
ti
o
n
a
n
d
S
ig
n
a
l
P
ro
c
e
ss
in
g
A
lg
o
rit
h
m
,
”
(Un
iv
e
rsit
y
o
f
A
th
e
n
s)
a
n
d
S
.
T
h
e
o
d
o
ri
d
is
(Un
iv
e
rsity
o
f
P
a
tras
)
P
re
n
ti
c
e
Ha
ll
In
c
.
,
(1
9
9
3
).
[1
2
]
A
.
Bu
a
d
e
s,
B.
Co
ll
,
a
n
d
J.
M
.
M
o
re
l,
“
A
R
e
v
ie
w
o
f
I
m
a
g
e
D
e
n
o
i
sin
g
A
l
g
o
rit
h
m
s,
W
it
h
A
Ne
w
O
n
e
,
”
M
u
lt
isc
a
le
M
o
d
e
li
n
g
A
n
d
S
im
u
latio
n
,
V
o
l.
4
,
No
.
2
,
P
p
.
4
9
0
-
5
3
0
,
(2
0
0
5
).
[1
3
]
Hu
a
n
g
,
Y.J.
W
a
n
g
,
Y.
W
.
M
e
n
g
,
F
.
J.
W
a
n
g
,
G
.
L
.
,
“
A
sp
a
ti
a
l
sp
e
c
t
ru
m
e
sti
m
a
ti
o
n
a
lg
o
rit
h
m
b
a
se
d
o
n
a
d
a
p
ti
v
e
b
e
a
m
f
o
r
m
in
g
n
u
ll
in
g
,
”
In
telli
g
e
n
t
Co
n
t
ro
l
a
n
d
In
fo
rm
a
ti
o
n
Pro
c
e
ss
in
g
(
ICICIP),
2
0
1
3
Fo
u
rth
In
ter
n
a
ti
o
n
a
l
Co
n
fer
e
n
c
e
,
p
p
.
2
2
0
–
2
2
4
,
J
u
n
e
(
2
0
1
3
).
[1
4
]
M
a
rk
R
G
,
S
c
h
lu
ter
P
S
,
M
o
o
d
y
G
B,
De
v
li
n
,
P
H,
Ch
e
rn
o
f
f
,
D
.
,
“
A
n
a
n
n
o
tate
d
ECG
d
a
tab
a
se
f
o
r
e
v
a
lu
a
ti
n
g
a
rrh
y
th
m
ia d
e
tec
to
rs
,
”
I
EE
E
T
ra
n
sa
c
ti
o
n
s
o
n
Bi
o
me
d
ica
l
E
n
g
in
e
e
ri
n
g
2
9
(
8
):
6
0
0
(1
9
8
2
).
[1
5
]
M
o
o
d
y
G
B,
M
a
rk
RG
.
T
h
e
M
IT
-
BIH
A
rrh
y
th
m
ia
Da
tab
a
se
o
n
CD
-
ROM
a
n
d
s
o
f
twa
re
f
o
r
u
se
w
it
h
it
.
Co
m
p
u
ters
in
Ca
rd
i
o
lo
g
y
1
7
:1
8
5
-
1
8
8
(
1
9
9
0
).
[1
6
]
h
tt
p
:
//
ww
w
.
p
h
y
sio
n
e
t.
o
rg
/p
h
y
sio
b
a
n
k
/
d
a
tab
a
se
/m
it
d
b
.
Evaluation Warning : The document was created with Spire.PDF for Python.