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c
o
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1.
I
NT
RO
D
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I
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R
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is
a
f
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d
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d
to
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y
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y
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m
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d
y
n
a
m
ical
s
y
s
te
m
s
a
n
d
an
al
y
s
i
s
[
1
]
.
Hu
m
a
n
b
o
d
y
also
co
m
p
r
is
e
s
o
f
v
i
tal
o
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g
an
s
li
k
e
b
r
ain
,
w
h
ich
p
r
o
d
u
ce
s
E
E
G
s
ig
n
al
s
.
T
h
ese
s
ig
n
al
s
ar
e
h
ig
h
l
y
r
an
d
o
m
a
n
d
d
y
n
a
m
ical
i
n
n
at
u
r
e
an
d
ar
e
d
if
f
ic
u
lt
to
a
n
al
y
s
e
b
y
co
n
v
en
t
io
n
a
l
m
et
h
o
d
s
as
t
h
e
c
h
a
n
g
e
s
o
cc
u
r
at
v
er
y
s
h
o
r
t
d
u
r
atio
n
s
.
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n
ce
m
an
y
d
i
s
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r
d
er
s
m
an
if
e
s
t
th
e
m
s
el
v
e
s
i
n
t
h
e
p
atter
n
s
a
n
d
s
y
n
ch
r
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n
izatio
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o
f
t
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ese
r
a
n
d
o
m
s
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g
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al
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(
li
k
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E
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an
d
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C
G
s
s
i
g
n
a
l)
,
th
e
co
n
ce
p
t
o
f
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ce
ca
n
b
e
u
s
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a
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d
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d
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y
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p
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e
n
o
m
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n
o
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al
s
.
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d
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s
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lo
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u
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is
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u
m
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o
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etu
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ed
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o
s
e
o
n
l
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t
y
p
e
o
f
d
is
o
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er
,
an
d
s
o
m
e
o
f
th
e
m
also
r
eq
u
ir
e
a
s
en
s
o
r
o
r
a
d
ev
ice
to
b
e
i
m
p
la
n
ted
in
s
id
e
a
h
u
m
a
n
b
o
d
y
f
o
r
tak
i
n
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in
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s
,
w
h
ic
h
ca
n
b
e
th
e
ca
u
s
e
o
f
i
n
f
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tio
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s
.
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er
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e
e
x
i
s
ti
n
g
d
iag
n
o
s
tic
m
eth
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d
s
also
r
eq
u
ir
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s
g
r
ea
t
ex
p
er
tis
e
f
o
r
ta
k
i
n
g
th
e
r
ea
d
in
g
s
a
n
d
an
al
y
zi
n
g
t
h
e
m
[2
-
4
]
.
T
h
is
p
ap
er
g
iv
es
th
e
k
ee
n
i
n
s
i
g
h
t
o
f
t
h
e
p
r
o
ce
s
s
o
f
r
ec
u
r
r
en
ce
in
h
u
m
a
n
b
o
d
y
a
n
d
p
r
o
p
o
s
es
a
n
o
v
e
l
m
et
h
o
d
to
d
etec
t
th
e
n
eu
r
o
lo
g
ical
d
is
o
r
d
er
s
li
k
e
ep
ilep
tic
s
eizu
r
es,
Alzh
e
i
m
er
’
s
d
i
s
ea
s
e
etc.
T
h
e
p
r
o
p
o
s
ed
m
et
h
o
d
u
s
es
t
h
e
co
n
ce
p
t
o
f
r
ec
u
r
r
en
ce
an
d
tells
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h
e
d
eg
r
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f
co
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p
lin
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y
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ch
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is
m
b
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tak
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f
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m
v
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er
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o
s
itio
n
s
f
r
o
m
t
h
e
h
u
m
a
n
b
r
ain
[
5
]
.
A
p
ar
a
m
eter
ca
lled
th
e”
s
y
n
ch
r
o
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izatio
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I
n
d
ex
”,
i
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to
d
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,
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4
,
A
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s
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7
5
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2759
2752
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Sig
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Dete
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e
p
h
y
s
io
lo
g
ical
s
tat
e
b
y
a
n
al
y
s
i
s
o
f
th
e
co
r
r
esp
o
n
d
in
g
co
m
p
le
x
s
i
g
n
al
s
.
S
y
n
c
h
r
o
n
izatio
n
a
n
d
r
elate
d
p
h
en
o
m
e
n
a
i
n
co
u
p
led
co
m
p
le
x
s
y
s
te
m
s
h
av
e
b
ee
n
f
o
u
n
d
to
o
cc
u
r
,
n
o
t
o
n
l
y
i
n
p
h
y
s
ical,
b
u
t
al
s
o
in
m
an
y
b
io
lo
g
ica
l
s
y
s
te
m
s
,
e.
g
.
,
t
h
e
ca
r
d
io
r
esp
ir
ato
r
y
i
n
ter
ac
tio
n
a
n
d
n
e
u
r
al
s
i
g
n
al
s
.
Me
as
u
r
es
o
f
co
m
p
lex
i
t
y
h
av
e
b
ee
n
d
ev
elo
p
ed
th
at
d
is
tin
g
u
is
h
b
et
w
ee
n
r
eg
u
lar
,
c
h
ao
tic,
an
d
r
an
d
o
m
b
eh
a
v
io
r
s
,
a
n
d
ca
n
tr
y
to
p
r
ed
ict
a
h
ea
r
t
attac
k
o
r
ep
ilep
tic
s
eizu
r
e
.
I
t
h
as
b
ee
n
r
ep
o
r
ted
th
at
co
m
p
lex
it
y
o
f
h
ea
r
t
an
d
b
r
ai
n
d
ata
ca
n
d
is
ti
n
g
u
is
h
h
ea
lth
y
a
n
d
s
i
ck
s
u
b
j
ec
ts
an
d
s
o
m
eti
m
es
ev
e
n
p
r
ed
ict
h
e
ar
t
attac
k
o
r
ep
ilep
tic
s
eiz
u
r
e
.
T
h
e
m
ain
t
y
p
es
o
f
co
m
p
lex
it
y
p
ar
am
eter
s
ar
e
en
tr
o
p
ies,
f
r
ac
tal
d
i
m
e
n
s
io
n
s
,
an
d
L
y
ap
u
n
o
v
e
x
p
o
n
en
t
s
.
2.
No
n
L
i
n
ea
r
s
i
g
n
a
l
p
r
o
ce
s
s
i
n
g
:
Dep
en
d
in
g
o
n
t
h
e
n
atu
r
e
o
f
t
h
e
s
y
s
te
m
s
,
t
h
er
e
ar
e
d
if
f
er
en
t
r
eq
u
ir
e
m
e
n
ts
to
th
e
m
et
h
o
d
s
.
W
h
ile
li
n
ea
r
m
et
h
o
d
s
b
ased
o
n
co
r
r
elatio
n
s
ar
e
n
o
t
s
u
f
f
icie
n
t
to
d
ea
l
w
it
h
n
o
n
li
n
ea
r
d
ep
en
d
en
cies,
m
o
s
t
n
o
n
li
n
ea
r
m
et
h
o
d
s
r
eq
u
ir
e
s
u
f
f
icie
n
tl
y
lo
n
g
s
tatio
n
ar
y
ti
m
e
s
er
ies.
F
o
r
th
e
ca
s
e
t
h
at
s
tatio
n
ar
it
y
h
o
ld
s
o
n
l
y
f
o
r
s
h
o
r
t
o
b
s
er
v
atio
n
ti
m
e,
cr
o
s
s
r
ec
u
r
r
en
ce
p
lo
ts
(
C
R
P
s
)
w
er
e
in
tr
o
d
u
ce
d
.
Ho
w
e
v
er
,
th
i
s
m
et
h
o
d
is
b
as
ed
o
n
tak
i
n
g
d
is
ta
n
ce
s
o
f
tr
aj
ec
to
r
ies,
w
h
ic
h
i
s
co
n
ce
p
t
u
a
ll
y
d
i
f
f
icu
lt
o
n
p
h
y
s
icall
y
d
if
f
er
en
t
s
y
s
te
m
s
.
A
g
e
n
er
al
p
r
o
b
lem
i
n
s
tu
d
y
i
n
g
m
u
l
tiv
ar
iate
d
ata
f
r
o
m
n
at
u
r
al
s
y
s
te
m
s
,
f
o
r
in
s
ta
n
ce
E
E
G
d
ata,
is
th
a
t
m
e
asu
r
e
m
en
t
co
n
d
itio
n
s
c
h
a
n
g
e
w
it
h
ti
m
e.
Am
o
n
g
o
t
h
er
s
o
f
f
s
et
an
d
a
m
p
lit
u
d
e
r
an
g
e
ca
n
v
ar
y
d
i
f
f
er
e
n
tl
y
w
i
th
i
n
th
e
c
h
an
n
el
s
.
T
o
o
v
er
co
m
e
th
is
p
r
o
b
lem
w
e
h
a
v
e
co
n
s
id
er
a
s
p
ec
ial
s
y
m
b
o
lic
d
y
n
a
m
ics
o
f
th
e
s
y
s
te
m
,
w
h
er
e
th
e
ti
m
e
s
er
ies
i
s
en
co
d
ed
b
y
o
r
d
er
p
atter
n
s
.
T
h
is
y
ie
ld
s
f
u
r
t
h
er
s
y
m
b
o
l seq
u
e
n
ce
s
,
w
h
ich
ar
e
i
n
v
ar
ia
n
t
w
it
h
r
esp
ec
t to
ce
r
tain
d
is
to
r
tio
n
s
i
n
a
m
p
lit
u
d
e.
2.
RE
CUR
RE
NC
E
S
T
h
e
co
n
ce
p
t
o
f
r
ec
u
r
r
en
ce
g
o
es
b
ac
k
to
P
o
in
ca
r
e,
w
h
o
p
r
o
v
ed
th
at
a
f
ter
a
s
u
f
f
icie
n
tl
y
l
o
n
g
ti
m
e,
th
e
tr
aj
ec
to
r
y
o
f
a
ch
ao
tic
s
y
s
te
m
in
p
h
a
s
e
s
p
ac
e
w
i
ll
r
etu
r
n
ar
b
itra
r
ily
clo
s
e
to
an
y
f
o
r
m
e
r
p
o
in
t
o
f
its
r
o
u
te
w
it
h
p
r
o
b
ab
ilit
y
o
n
e.
2
.
1
.
T
y
pes
o
f
re
curr
ence
s
T
h
e
ty
p
es o
f
r
ec
u
r
r
en
ce
s
ca
n
b
e
ex
p
lain
ed
b
r
ief
l
y
b
y
t
h
e
T
ab
le
1
.
R
e
c
u
r
r
e
n
c
e
M
a
t
r
i
x
C
r
o
ss
R
e
c
u
r
r
e
n
c
e
M
a
t
r
i
x
Jo
i
n
t
R
e
c
u
r
r
e
n
c
e
M
a
t
r
i
x
O
r
d
e
r
R
e
c
u
r
r
e
n
c
e
M
a
t
r
i
x
R
ij
=
Θ
(
ε
−
∥
x
i
−
x
j
∥
)
CR
ij
=
Θ
(
ε
−
∥
x
i
−
y
j
∥
)
JR
ij
xy
=
R
ij
x
∗
R
ij
y
O
R
P
(
t
,
τ)
=
1
,
π
x
(
t
)
=
π
y
(
t
+
τ)
0
,
o
t
h
e
r
w
i
se
*
π
x
(
t
)
=
1
,
i
f
x
(
t
)
>
x
(
t
+
τ)
τ=
d
e
l
a
y
Her
e,
ε=
1
0
% o
f
th
e
m
a
x
i
m
u
m
v
al
u
e
o
f
th
e
s
i
g
n
al
o
v
er
a
g
i
v
e
n
in
te
r
v
al
o
f
ti
m
e
x
i,
x
j
ar
e
th
e
i
th
an
d
j
th
s
a
m
p
le
o
f
th
e
s
a
m
e
s
i
g
n
al
s
er
ies an
d
R
ij
is
th
e
r
ec
u
r
r
en
ce
m
atr
i
x
x
i,
y
j
ar
e
t
w
o
d
if
f
er
e
n
t
s
a
m
p
le
s
o
f
t
w
o
d
i
f
f
er
en
t
s
i
g
n
al
s
er
ie
s
b
et
w
ee
n
w
h
ic
h
r
ec
u
r
r
en
ce
n
ee
d
s
to
f
o
u
n
d
a
n
d
CR
ij
r
e
f
er
s
to
th
e
cr
o
s
s
r
ec
u
r
r
e
n
ce
R
ec
u
r
r
en
ce
s
i
n
B
io
Me
d
ical
Sig
n
a
ls
:
T
h
e
b
io
m
ed
ical
s
i
g
n
al
s
lik
e
E
C
G
an
d
E
E
G
ar
e
h
i
g
h
l
y
r
an
d
o
m
in
n
a
tu
r
e
a
n
d
v
ar
y
v
er
y
m
u
ch
ev
en
i
n
s
h
o
r
t
ti
m
e
d
u
r
atio
n
.
Su
p
er
f
icia
ll
y
,
i
t
s
ee
m
s
t
h
at
t
h
er
e
is
n
o
p
atter
n
i
n
E
E
G
s
i
g
n
al
s
,
b
u
t
w
h
en
o
b
s
er
v
ed
clo
s
el
y
o
v
er
th
e
ti
m
e
li
m
i
ted
s
a
m
p
le
s
w
h
ic
h
ar
e
o
b
tain
e
d
b
y
d
ig
i
tizin
g
a
n
d
f
ilter
i
n
g
o
n
e
ca
n
f
in
d
t
h
at
,
t
h
e
r
e
ar
e
ce
r
tain
p
atter
n
s
o
f
r
ep
etitio
n
s
o
r
r
ec
u
r
r
en
ce
s
i
n
E
E
G
s
ig
n
al
s
tak
e
n
f
r
o
m
v
ar
io
u
s
p
o
s
itio
n
s
o
f
b
r
ai
n
u
s
in
g
E
E
G
m
ac
h
i
n
e.
T
h
e
r
ec
u
r
r
en
ce
b
et
w
ee
n
a
n
y
t
w
o
ti
m
e
s
er
ies
o
f
b
io
m
ed
ical
s
ig
n
a
ls
ca
n
b
e
f
o
u
n
d
b
y
ab
o
v
e
m
en
tio
n
e
d
m
et
h
o
d
s
.
T
h
er
e
ar
e
v
ar
io
u
s
ex
is
t
in
g
m
eth
o
d
s
to
a
n
al
y
ze
th
e
b
io
m
ed
ical
s
ig
n
als
b
y
u
s
in
g
th
e
co
n
ce
p
t
o
f
r
ec
u
r
r
en
ce
s
.
So
m
e
o
f
th
e
m
ar
e
as f
o
llo
w
s
:
Evaluation Warning : The document was created with Spire.PDF for Python.
I
n
t J
E
lec
&
C
o
m
p
E
n
g
I
SS
N:
2
0
8
8
-
8708
A
n
o
ve
l a
p
p
r
o
a
c
h
fo
r
d
etec
tio
n
o
f n
e
u
r
o
lo
g
ica
l d
is
o
r
d
ers
th
r
o
u
g
h
elec
tr
i
ca
l …
(
Mo
h
d
S
u
h
a
ib
K
id
w
a
i
)
2753
2
.
2
.
Dec
o
m
po
s
it
io
n
m
o
del (
ba
s
ed
o
n c
o
up
lin
g
)
T
h
e
f
o
r
m
o
f
a
co
u
p
li
n
g
f
u
n
cti
o
n
d
ep
en
d
s
o
n
th
e
d
if
f
er
i
n
g
co
n
tr
ib
u
tio
n
s
f
r
o
m
i
n
d
iv
id
u
al
o
s
cillatio
n
s
.
C
h
a
n
g
es
i
n
f
o
r
m
m
a
y
d
ep
en
d
p
r
ed
o
m
in
a
n
tl
y
o
n
o
n
l
y
o
n
e
o
f
th
e
p
h
a
s
es
(
alo
n
g
o
n
e
-
a
x
is
)
,
o
r
th
e
y
m
a
y
d
ep
en
d
o
n
b
o
th
p
h
a
s
es,
o
f
te
n
r
es
u
lti
n
g
i
n
a
co
m
p
licated
an
d
in
t
u
it
iv
el
y
u
n
c
lear
d
ep
en
d
en
ce
.
T
h
is
m
o
d
el
m
a
in
l
y
ta
k
e
s
p
h
ase
i
n
to
co
n
s
id
er
atio
n
,
t
h
o
u
g
h
a
m
p
lit
u
d
e
d
y
n
a
m
ics
ca
n
also
b
e
ta
k
en
in
to
co
n
s
id
er
a
tio
n
.
T
h
e
co
u
p
li
n
g
b
et
w
ee
n
th
e
v
ar
io
u
s
s
ig
n
als
o
r
th
e
r
ec
u
r
r
en
ce
s
is
f
o
u
n
d
o
u
t
an
d
d
is
o
r
d
er
s
ar
e
d
iag
n
o
s
ed
o
n
th
e
b
asi
s
o
f
co
u
p
lin
g
s
tr
e
n
g
t
h
[
3
-
6
]
.
P
r
ev
io
u
s
co
u
p
li
n
g
tr
ea
t
m
en
ts
,
in
cl
u
d
in
g
t
h
e
cr
o
s
s
-
f
r
eq
u
e
n
c
y
co
u
p
lin
g
i
n
n
eu
r
o
s
cie
n
ce
,
h
a
v
e
f
o
cu
s
ed
o
n
th
e
n
et
co
u
p
li
n
g
i
n
o
n
e
d
ir
ec
tio
n
.
I
n
th
is
m
o
d
el,
w
e
d
ec
o
m
p
o
s
e
t
h
e
n
et
co
u
p
li
n
g
i
n
t
o
t
w
o
co
m
p
o
n
e
n
t
s
d
ep
en
d
in
g
o
n
t
h
eir
f
u
n
c
tio
n
a
l
r
o
les:
th
e
d
ir
ec
t
an
d
th
e
in
d
ir
ec
t
co
u
p
lin
g
s
.
Dir
ec
t
-
co
u
p
lin
g
d
escr
ib
es
th
e
in
f
lu
e
n
ce
o
f
th
e
d
ir
ec
t
(
u
n
id
ir
ec
tio
n
al)
d
r
iv
i
n
g
t
h
at
o
n
e
o
s
ci
llato
r
ex
er
ts
o
n
th
e
o
th
er
.
A
r
g
u
ab
l
y
,
it
i
s
t
h
e
m
o
s
t
s
tu
d
ied
i
n
ter
ac
tio
n
i
n
p
h
y
s
io
l
o
g
y
,
o
f
te
n
li
n
k
ed
to
m
o
d
u
lat
i
o
n
m
ec
h
a
n
i
s
m
s
.
T
h
e
s
ec
o
n
d
c
o
m
p
o
n
en
t,
in
d
ir
ec
t
-
co
u
p
lin
g
,
o
f
te
n
ca
lled
co
m
m
o
n
-
co
u
p
li
n
g
,
an
d
d
ep
en
d
s
o
n
th
e
s
h
ar
ed
co
n
tr
ib
u
tio
n
s
o
f
t
h
e
t
w
o
o
s
cillatio
n
s
.
T
h
e
in
d
i
r
ec
t
co
u
p
lin
g
al
s
o
in
cl
u
d
es
t
h
e
d
if
f
u
s
i
v
e
co
u
p
lin
g
g
i
v
e
n
w
it
h
t
h
e
p
h
ase
d
if
f
er
e
n
ce
ter
m
s
.
T
h
e
m
e
c
h
a
n
is
m
b
eh
in
d
t
h
is
c
o
u
p
lin
g
co
m
p
o
n
e
n
t
o
r
p
r
o
ce
s
s
,
alth
o
u
g
h
w
e
p
r
ese
n
t
th
e
m
o
d
el
in
r
elatio
n
to
p
h
ase
d
y
n
a
m
ic
s
,
a
s
i
m
ilar
f
u
n
ct
io
n
al
d
ec
o
m
p
o
s
itio
n
o
f
t
h
e
co
u
p
lin
g
s
ca
n
al
s
o
b
e
ap
p
lied
to
am
p
litu
d
e
d
y
n
a
m
ics.
I
n
ter
m
s
o
f
t
h
e
g
e
n
er
al
th
eo
r
y
o
f
p
h
ase
d
y
n
a
m
ics
a
n
d
eq
u
atio
n
,
th
e
co
u
p
lin
g
f
u
n
ctio
n
q
1
(
ϕ
1
,
ϕ
2
)
ca
n
b
e
ex
p
r
ess
ed
as th
e
p
r
o
d
u
ct
o
f
t
w
o
f
u
n
ctio
n
s
[4
-
12]
q
1
(
ϕ
1
,
ϕ
2
)
=P
1
(ϕ
1)
P
2
(
ϕ
2
)
w
h
er
e
P
1
(ϕ
1
)
is
th
e
p
h
ase
r
esp
o
n
s
e
c
u
r
v
e
(
P
R
C
)
o
f
t
h
e
f
ir
s
t
o
s
cillato
r
an
d
s
h
o
w
s
h
o
w
it
r
e
s
p
o
n
d
s
to
e
x
ter
n
a
l
p
er
tu
r
b
atio
n
s
,
w
h
i
le
P
2
(ϕ
2
)
is
th
e
p
er
tu
r
b
atio
n
f
u
n
ctio
n
th
r
o
u
g
h
w
h
ic
h
th
e
s
ec
o
n
d
o
s
cillat
o
r
ac
ts
o
n
th
e
f
ir
s
t
o
n
e
.
2
.
3
.
Sig
na
l pro
ce
s
s
ing
a
nd
s
t
a
t
is
t
ica
l a
na
ly
s
is
T
h
e
s
ig
n
als
w
er
e
f
ir
s
t
in
s
p
ec
ted
v
is
u
all
y
,
f
o
llo
w
ed
b
y
a
u
to
m
ated
ar
ti
f
ac
t
r
e
m
o
v
al
b
y
i
n
t
er
p
o
latio
n
.
Data
f
r
o
m
s
u
b
j
ec
ts
w
h
o
s
e
s
i
g
n
als
h
ad
m
a
n
y
ar
ti
f
ac
ts
w
er
e
d
is
r
eg
ar
d
ed
an
d
n
o
t a
n
al
y
ze
d
.
T
h
e
cr
o
s
s
-
f
r
eq
u
en
c
y
in
ter
v
a
ls
w
er
e
esti
m
ated
b
y
s
t
an
d
ar
d
d
ig
ital
f
ilter
i
n
g
p
r
o
ce
d
u
r
es,
in
cl
u
d
in
g
a
FIR
f
i
lter
f
o
llo
w
ed
b
y
a
ze
r
o
-
p
h
ase
d
ig
ital
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ilter
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n
g
p
r
o
ce
d
u
r
e
to
en
s
u
r
e
t
h
at
n
o
ti
m
e
o
r
p
h
ase
lag
s
w
er
e
in
tr
o
d
u
c
e
d
b
y
th
e
f
i
lter
in
g
.
T
h
e
b
o
u
n
d
ar
ies
o
f
t
h
e
i
n
ter
v
a
ls
e
x
tr
ac
ted
f
r
o
m
t
h
e
E
E
G
s
ig
n
al
w
er
e
δ
=0
.
8
–
4
Hz,
θ
=4
–
7
.
5
Hz,
α
=7
.
5
–
1
4
Hz,
β
=1
4
–
2
2
Hz
an
d
γ
=2
2
–
1
0
0
Hz
;
th
e
in
ter
v
al
ex
tr
ac
ted
f
r
o
m
t
h
e
r
esp
ir
atio
n
s
ig
n
al
w
as
r
=0
.
1
4
5
–
0
.
6
Hz;
an
d
th
e
ex
tr
ac
tio
n
o
f
t
h
e
h
ea
r
t
ac
tiv
i
t
y
f
r
o
m
th
e
E
C
G
s
i
g
n
al
w
as
h
=0
.
6
–
2
Hz.
W
av
elet
p
o
w
er
an
d
co
h
er
en
ce
an
al
y
s
e
s
,
to
g
eth
er
w
it
h
f
u
r
t
h
er
clin
ical
in
ter
p
r
etatio
n
,
w
ill
b
e
p
r
esen
ted
else
w
h
er
e.
Fo
r
th
e
E
E
G
o
s
cillatio
n
s
s
p
ec
ial
ca
r
e
w
as
tak
e
n
in
d
ea
li
n
g
w
i
t
h
f
r
eq
u
e
n
c
y
s
p
illag
e
b
et
w
ee
n
in
ter
v
a
ls
,
h
ea
r
t
ar
tif
ac
ts
an
d
p
o
w
er
lin
e
ar
ti
f
ac
ts
.
T
h
en
th
e
co
u
p
li
n
g
b
et
w
ee
n
th
ese
o
b
tain
ed
E
C
G
s
ig
n
al
s
an
d
th
o
s
e
o
b
tai
n
ed
f
r
o
m
E
E
G
m
ac
h
in
e
is
s
t
u
d
ied
an
d
co
m
p
ar
ed
w
ith
t
h
e
s
ta
n
d
ar
d
v
alu
e
s
o
f
v
ar
io
u
s
s
tati
s
tical
p
ar
a
m
eter
s
,
w
h
ic
h
ar
e
o
b
tain
ed
f
r
o
m
t
h
e
h
ea
lt
h
y
p
er
s
o
n
.
Fo
llo
w
i
n
g
p
ar
a
m
eter
s
ca
n
b
e
u
s
ed
to
s
tu
d
y
th
e
r
ec
u
r
r
en
ce
p
atter
n
i
n
th
e
b
io
m
ed
ical
s
ig
n
als:
a.
Dete
r
m
i
n
is
m
(
DE
T
)
:
T
h
ese
m
ea
s
u
r
es
ar
e
b
ased
o
n
th
e
h
i
s
to
g
r
a
m
P
(
l
)
o
f
d
iag
o
n
a
l
lin
es
o
f
len
g
t
h
l
.
P
r
o
ce
s
s
es
w
it
h
u
n
co
r
r
elate
d
o
r
w
ea
k
l
y
co
r
r
elate
d
,
s
to
ch
ast
ic
o
r
ch
ao
tic
b
eh
av
io
r
ca
u
s
e
n
o
n
e
o
r
v
er
y
s
h
o
r
t
d
iag
o
n
als,
w
h
er
ea
s
d
eter
m
i
n
i
s
tic
p
r
o
ce
s
s
es
ca
u
s
e
lo
n
g
er
d
iag
o
n
al
s
an
d
les
s
s
i
n
g
le,
i
s
o
lated
r
ec
u
r
r
en
ce
p
o
in
ts
.
T
h
er
ef
o
r
e,
th
e
r
atio
o
f
r
ec
u
r
r
en
ce
p
o
in
ts
th
a
t
f
o
r
m
d
i
ag
o
n
al
s
tr
u
ct
u
r
es (
o
f
m
in
i
m
u
m
le
n
g
th
l
m
in
)
to
all
r
ec
u
r
r
en
ce
p
o
in
ts
i
s
in
tr
o
d
u
ce
d
as a
m
ea
s
u
r
e
f
o
r
d
eter
m
in
i
s
m
(
o
r
p
r
ed
ictab
ilit
y
)
o
f
t
h
e
s
y
s
te
m
.
A
d
ia
g
o
n
al
li
n
e
o
f
len
g
t
h
l
m
ea
n
s
t
h
at
a
s
e
g
m
e
n
t
o
f
t
h
e
tr
aj
ec
to
r
y
is
r
at
h
er
clo
s
e
d
u
r
in
g
1
t
i
m
e
s
tep
to
an
o
th
er
s
e
g
m
en
t
o
f
t
h
e
tr
aj
ec
to
r
y
at
a
d
i
f
f
er
en
t
ti
m
e;
th
u
s
,
t
h
ese
li
n
es
ar
e
r
elate
d
to
t
h
e
d
iv
er
g
e
n
ce
o
f
t
h
e
tr
aj
ec
to
r
y
s
e
g
m
e
n
t
s
.
T
h
e
av
e
r
ag
e
d
iag
o
n
a
l
li
n
e
le
n
g
th
is
th
e
a
v
er
ag
e
t
i
m
e
t
h
at
t
w
o
s
eg
m
e
n
t
s
o
f
th
e
tr
aj
ec
to
r
y
ar
e
clo
s
e
to
ea
ch
o
th
er
,
an
d
ca
n
b
e
in
ter
p
r
eted
as th
e
m
ea
n
p
r
ed
ictio
n
ti
m
e.
b.
Me
asu
r
es
b
ased
o
n
v
er
tical
li
n
es:
T
h
ese
m
ea
s
u
r
es
ar
e
b
ase
d
o
n
th
e
h
is
to
g
r
a
m
P
(
v
)
o
f
v
er
tical
lin
e
s
o
f
len
g
th
v
.
T
h
e
r
atio
b
et
w
ee
n
t
h
e
r
ec
u
r
r
en
ce
p
o
in
t
s
f
o
r
m
in
g
th
e
v
er
tical
s
tr
u
c
tu
r
es
a
n
d
t
h
e
en
t
ir
e
s
et
o
f
r
ec
u
r
r
en
ce
p
o
in
ts
i
s
ca
lled
la
m
in
ar
it
y
[
1
3
]
.
T
h
e
co
m
p
u
tatio
n
o
f
L
AM
is
r
ea
lized
f
o
r
th
o
s
e
v
th
at
ex
c
ee
d
a
m
in
i
m
a
l
len
g
th
v
m
in
i
n
o
r
d
er
t
o
d
ec
r
ea
s
e
th
e
i
n
f
l
u
e
n
ce
o
f
t
h
e
tan
g
en
tia
l
m
o
tio
n
.
L
A
M
r
ep
r
esen
ts
th
e
o
cc
u
r
r
en
ce
o
f
la
m
i
n
ar
s
tate
s
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th
e
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y
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te
m
w
i
th
o
u
t
d
escr
ib
in
g
t
h
e
len
g
t
h
o
f
th
e
s
e
la
m
i
n
ar
p
h
ases
.
I
t
w
ill
d
ec
r
ea
s
e
if
t
h
e
R
P
co
n
s
is
ts
o
f
m
o
r
e
s
in
g
le
r
ec
u
r
r
en
ce
p
o
in
ts
th
a
n
v
er
tical
s
tr
u
ct
u
r
es.
T
h
e
a
v
er
a
g
e
le
n
g
th
o
f
v
er
tical
s
tr
u
ctu
r
e
s
is
ca
lled
tr
ap
p
in
g
ti
m
e
(
T
T
)
.
Evaluation Warning : The document was created with Spire.PDF for Python.
I
SS
N
:
2
0
8
8
-
8708
I
n
t J
E
lec
&
C
o
m
p
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n
g
,
Vo
l.
9
,
No
.
4
,
A
u
g
u
s
t 2
0
1
9
:
2
7
5
1
-
2759
2754
2
.
3
.
T
he
pro
po
s
ed
m
et
ho
d
T
h
e
m
at
h
e
m
a
tical
co
n
ce
p
t
o
f
r
ec
u
r
r
en
ce
i
s
t
h
e
cr
u
x
o
f
th
e
a
lg
o
r
ith
m
.
T
h
e
E
E
G
s
i
g
n
als
f
r
o
m
v
ar
io
u
s
ch
an
n
el
s
o
f
E
E
G
m
ac
h
i
n
e
ar
e
tak
en
as
a
n
i
n
p
u
t
w
h
ic
h
w
il
l
b
e
u
s
ed
b
y
t
h
e
p
r
o
g
r
a
m
i
n
M
A
T
L
A
B
.
T
h
is
p
r
o
g
r
a
m
w
ill
b
e
b
ased
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n
t
h
e
p
r
o
p
o
s
ed
alg
o
r
ith
m
a
n
d
b
asicall
y
co
m
p
ar
e
s
th
e
s
y
n
c
h
r
o
n
is
m
b
et
w
ee
n
th
e
E
E
G
s
ig
n
als
o
f
a
n
y
t
w
o
c
h
an
n
els.
T
h
is
co
m
p
ar
is
o
n
is
d
o
n
e
b
y
u
s
i
n
g
t
h
e
co
n
ce
p
t
o
f
r
ec
u
r
r
en
ce
.
Seco
n
d
th
i
n
g
is
to
f
i
n
d
th
e
d
eg
r
ee
o
f
r
ec
u
r
r
e
n
ce
w
h
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h
i
s
f
o
u
n
d
o
u
t b
y
u
s
i
n
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th
e
f
o
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m
u
la
o
f
s
y
n
ch
r
o
n
izati
o
n
in
d
ex
ρ
π
[
1
4
]
.
T
h
e
ad
v
an
tag
e
o
f
u
s
i
n
g
s
y
n
c
h
r
o
n
izatio
n
in
d
e
x
in
t
h
i
s
alg
o
r
it
h
m
i
s
th
a
t
it
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er
v
e
s
t
w
o
p
u
r
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o
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es,
f
ir
s
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y
it
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elp
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n
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n
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er
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ta
n
d
in
g
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h
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y
n
ch
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izatio
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b
et
w
ee
n
th
e
t
w
o
s
i
g
n
al
s
f
r
o
m
E
E
G
ch
a
n
n
els
a
n
d
s
ec
o
n
d
l
y
it
allo
w
s
t
h
e
u
s
er
to
f
in
d
t
h
e
d
eg
r
ee
o
f
s
y
n
ch
r
o
n
iza
ti
o
n
.
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s
i
n
g
t
h
e
p
lo
t
co
m
m
an
d
o
f
M
A
T
L
A
B
,
th
is
s
y
n
ch
r
o
n
izatio
n
i
n
d
ex
ca
n
b
e
s
h
o
w
n
in
f
o
r
m
o
f
g
r
ap
h
s
.
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f
th
e
g
r
ap
h
s
h
o
w
s
i
n
cr
ea
s
i
n
g
p
atter
n
,
it
s
h
o
w
s
h
ig
h
a
m
o
u
n
t
o
f
s
y
n
c
h
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n
izat
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n
b
et
w
ee
n
t
h
e
t
w
o
s
i
g
n
a
ls
else
th
e
lo
w
s
y
n
ch
r
o
n
izatio
n
.
Fo
llo
w
in
g
i
s
th
e
d
iag
r
a
m
m
atic
r
ep
r
esen
ta
tio
n
o
f
th
e
p
r
o
p
o
s
ed
alg
o
r
ith
m
f
o
r
b
etter
v
is
u
aliza
tio
n
an
d
u
n
d
er
s
t
an
d
in
g
[
1
5
-
27
]
Fig
u
r
e
1
.
T
h
e
b
lo
ck
d
iag
r
am
o
f
th
e
p
r
o
p
o
s
ed
alg
o
r
ith
m
T
h
e
s
tep
s
o
f
alg
o
r
ith
m
,
w
h
o
s
e
b
lo
ck
d
iag
r
a
m
is
d
ep
icted
as
Fig
u
r
e
1
,
ca
n
b
e
d
ef
in
ed
as f
o
l
lo
w
s
:
a.
T
h
e
s
ig
n
al
s
f
r
o
m
t
h
e
ch
a
n
n
els
o
f
E
E
G
m
ac
h
i
n
es
ar
e
tak
e
n
an
d
p
u
t
in
a
f
o
r
m
o
f
ar
r
a
y
s
o
th
at
it
ca
n
b
e
u
s
ed
as a
n
in
p
u
t.
b.
T
h
e
s
ig
n
al
s
f
r
o
m
t
h
e
ch
a
n
n
els
o
f
E
E
G
m
ac
h
i
n
es
ar
e
tak
e
n
an
d
p
u
t
in
a
f
o
r
m
o
f
ar
r
a
y
s
o
th
at
it
ca
n
b
e
u
s
ed
as a
n
in
p
u
t in
M
A
T
L
A
B
p
r
o
g
r
am
b
ased
o
n
t
h
is
al
g
o
r
ith
m
.
c.
p
ie
x
(
)
r
ef
er
s
to
th
e
o
r
d
er
p
att
er
n
an
d
it
is
f
o
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n
d
o
u
t
b
y
co
m
p
ar
in
g
s
a
m
p
les
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y
t
h
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e
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at
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er
e
n
t i
n
ter
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al
s
.
Si
m
ilar
l
y
p
ie
y
(
π
y
)
is
f
o
u
n
d
.
d.
On
ce
w
e
h
av
e
t
h
e
v
al
u
es
o
f
p
ie
x
an
d
p
ie
y
i
n
f
o
r
m
o
f
m
a
t
r
ices
n
e
x
t
s
tep
is
to
f
in
d
o
r
d
er
p
atter
n
.
I
t
i
s
f
o
u
n
d
as f
o
llo
w
s
:
OR
P
(
t,
τ
)
=
1
if
π
x
(
t)
=
π
y
(
t+τ
)
0
,
o
th
er
w
is
e
Nex
t
s
tep
is
to
f
in
d
o
u
t
t
h
e
r
ec
u
r
r
en
ce
r
ate
a
n
d
its
n
o
r
m
alize
d
v
al
u
e.
T
h
is
i
s
d
o
n
e
u
s
in
g
t
h
e
f
o
llo
w
i
n
g
f
o
r
m
u
las:
RR
(
τ
)
=
∑
R
(
t
,
τ
)
t
rr
(
τ
)
=
RR
(
τ
)
∑
RR
(
τ
)
τ
⁄
T
h
en
f
in
a
ll
y
a
p
ar
a
m
eter
ca
lled
“
s
y
n
c
h
r
o
n
izat
io
n
in
d
e
x
”
(ρ
π
)
is
f
o
u
n
d
an
d
p
lo
tted
.
T
h
e
f
o
r
m
u
la
f
o
r
s
y
n
ch
r
o
n
izatio
n
i
n
d
ex
i
s
as
f
o
llo
w
s
:
ρ
π
=1
-
(
−
∑
(
)
ln
(
)
ln
(
−
.
)
)
T
h
is
p
ar
am
eter
“ρ
π
”,
w
h
en
p
lo
tt
ed
b
etw
ee
n
it
s
t
w
o
ch
a
n
n
el
s
u
s
i
n
g
M
A
T
L
A
B
,
w
il
l
s
h
o
w
eit
h
er
h
i
g
h
,
m
o
d
er
ate,
lo
w
o
r
n
o
s
y
n
c
h
r
o
n
izatio
n
b
et
w
ee
n
t
h
e
s
i
g
n
a
ls
ta
k
en
f
r
o
m
d
if
f
er
e
n
t
ch
a
n
n
e
ls
o
f
E
E
G.
B
ased
o
n
th
e
v
alu
e
o
f
s
y
n
c
h
r
o
n
izatio
n
in
d
e
x
,
o
n
e
ca
n
co
m
p
ar
e
th
e
s
y
n
c
h
r
o
n
is
m
b
et
w
ee
n
E
E
G
s
i
g
n
al
s
o
b
tain
ed
f
r
o
m
th
e
d
if
f
er
e
n
t
ch
a
n
n
els
f
r
o
m
th
e
s
u
b
j
ec
t’
s
b
r
ain
.
Mo
r
eo
v
er
th
e
r
ec
u
r
r
en
ce
p
lo
ts
ar
e
also
p
lo
t
ted
w
h
ich
h
elp
s
i
n
b
etter
u
n
d
er
s
ta
n
d
in
g
o
f
s
y
n
ch
r
o
n
is
m
b
et
w
ee
n
t
h
e
E
E
G
[
28
-
30
].
Evaluation Warning : The document was created with Spire.PDF for Python.
I
n
t J
E
lec
&
C
o
m
p
E
n
g
I
SS
N:
2
0
8
8
-
8708
A
n
o
ve
l a
p
p
r
o
a
c
h
fo
r
d
etec
tio
n
o
f n
e
u
r
o
lo
g
ica
l d
is
o
r
d
ers
th
r
o
u
g
h
elec
tr
i
ca
l …
(
Mo
h
d
S
u
h
a
ib
K
id
w
a
i
)
2755
3.
RE
SU
L
T
S
A
ND
AN
AL
Y
SI
S
T
h
r
o
u
g
h
th
e
p
r
o
p
o
s
ed
alg
o
r
ith
m
,
ce
r
tai
n
p
r
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g
r
a
m
s
h
a
v
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m
ad
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w
h
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h
ta
k
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G
s
ig
n
al
s
o
f
p
atien
t
(
f
r
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m
d
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f
f
er
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t
c
h
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n
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e
ls
o
f
s
a
m
e
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G
m
ac
h
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es),
as
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n
p
u
t.
T
h
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h
as
b
ee
n
a
co
m
m
o
n
o
b
s
er
v
a
tio
n
in
m
o
s
t
o
f
th
e
n
eu
r
o
lo
g
ical
d
is
ea
s
es
t
h
at
at
ce
r
tain
p
o
in
t
o
f
ti
m
e,
t
h
e
E
E
G
s
ig
n
al
s
s
h
o
w
h
i
g
h
d
eg
r
ee
o
f
co
u
p
lin
g
o
r
s
y
n
c
h
r
o
n
izat
io
n
.
T
h
is
f
ea
t
u
r
e
is
ascer
tai
n
ed
w
ith
t
h
e
h
elp
o
f
r
ec
u
r
r
en
ce
p
l
o
t
an
d
th
e
p
lo
t
o
f
s
y
n
ch
r
o
n
izatio
n
/co
u
p
lin
g
i
n
d
e
x
to
d
etec
t t
h
e
d
is
o
r
d
er
s
.
T
h
e
r
esu
lt
s
f
o
r
s
o
m
e
o
f
t
h
e
n
eu
r
o
lo
g
ical
d
is
ea
s
e
ar
e
as
f
o
llo
w
s
:
a.
E
p
ilep
tic
s
eizu
r
e:
Usi
n
g
t
h
e
r
ec
u
r
r
en
ce
p
lo
t
an
d
t
h
e
co
u
p
l
in
g
i
n
d
ex
,
o
n
e
ca
n
ea
s
il
y
d
ete
ct
th
e
ep
ilep
tic
s
eizu
r
e
an
d
it
s
in
ten
s
it
y
.
T
h
e
O
R
P
an
d
th
e
co
u
p
li
n
g
i
n
d
ex
g
r
ap
h
o
f
a
p
er
s
o
n
w
ith
ep
ilep
s
y
is
s
h
o
w
n
u
n
d
er
:
T
w
o
E
E
G
s
i
g
n
als
ar
e
tak
e
n
f
r
o
m
d
if
f
er
en
t
c
h
a
n
n
el
s
as
s
h
o
w
n
i
n
Fi
g
u
r
e
s
2
a
n
d
3
.
Fi
g
u
r
e
4
s
h
o
w
s
t
h
at
th
er
e
ar
e
R
P
o
f
E
E
G
at
d
if
f
e
r
en
t
m
o
m
en
t
s
.
I
t
is
f
o
u
n
d
th
a
t
d
en
s
it
y
o
f
b
lack
d
o
ts
is
d
i
m
in
is
h
i
n
g
as
w
e
m
o
v
e
to
w
ar
d
s
s
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r
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o
m
e
n
t
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ll
y
R
P
h
as
v
er
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r
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e
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h
i
te
b
lack
d
o
ts
at
th
e
s
ei
zu
r
e
ac
tiv
it
y
i
n
Fig
u
r
es
5
an
d
6
.
T
h
is
i
s
also
s
h
o
w
n
t
h
r
o
u
g
h
r
ec
u
r
r
en
ce
r
ate
r
r
(
t)
an
d
co
u
p
lin
g
in
d
e
x
ρ
π
i
n
n
ex
t
f
i
g
u
r
e
s
.
T
h
e
in
cr
ea
s
in
g
tr
en
d
i
n
t
h
e
co
u
p
lin
g
i
n
d
ex
i
n
Fi
g
u
r
e
5
s
h
o
ws
h
i
g
h
d
eg
r
ee
o
f
co
u
p
li
n
g
o
r
s
y
n
c
h
r
o
n
izat
io
n
b
et
w
ee
n
E
E
G
s
i
g
n
al
s
ta
k
e
n
f
r
o
m
c
h
an
n
els.
T
h
is
h
ap
p
en
s
wh
en
t
h
e
p
er
s
o
n
is
s
u
f
f
er
i
n
g
f
r
o
m
ep
ilep
tic
f
i
ts
.
T
h
is
is
th
e
w
a
y
to
d
iag
n
o
s
e
ep
ilep
s
y
u
s
i
n
g
th
e
p
r
o
p
o
s
ed
m
et
h
o
d
.
Fig
u
r
e
2
.
E
E
G
s
ig
n
al
o
f
a
p
ati
en
t
w
it
h
E
p
ilep
s
y
f
r
o
m
C
h
a
n
n
e
l 1
o
f
E
E
G
m
ac
h
i
n
e
Fig
u
r
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3
.
E
E
G
s
ig
n
al
o
f
a
p
ati
en
t
w
it
h
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p
ilep
s
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f
r
o
m
C
h
a
n
n
e
l 1
7
o
f
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E
G
m
ac
h
in
e
Fig
u
r
e
4
.
R
P
o
f
E
E
G
at
d
if
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er
e
n
t
m
o
m
e
n
ts
Fig
u
r
e
5
.
S
y
n
c
h
r
o
n
izat
io
n
i
n
d
ex
g
r
ap
h
o
f
ab
o
v
e
p
atien
t
w
it
h
ep
ilep
s
y
Evaluation Warning : The document was created with Spire.PDF for Python.
I
SS
N
:
2
0
8
8
-
8708
I
n
t J
E
lec
&
C
o
m
p
E
n
g
,
Vo
l.
9
,
No
.
4
,
A
u
g
u
s
t 2
0
1
9
:
2
7
5
1
-
2759
2756
Fig
u
r
e
s
6
-
8
s
h
o
w
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th
e
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r
ap
h
o
f
s
y
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h
r
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izatio
n
in
d
e
x
.
T
h
e
ch
a
n
n
els
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h
e
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n
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E
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e.
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n
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ap
h
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p
lo
tted
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.
Si
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if
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o
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ith
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ical
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p
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r
ith
m
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a
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a
m
eter
“s
y
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n
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za
tio
n
I
n
d
ex
”,
s
o
o
b
v
io
u
s
l
y
t
h
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latter
ap
p
r
o
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h
is
s
i
m
p
ler
as c
o
m
p
ar
ed
to
th
e
f
o
r
m
er
o
n
e.
Evaluation Warning : The document was created with Spire.PDF for Python.
I
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N
:
2
0
8
8
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8708
I
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&
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l.
9
,
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.
4
,
A
u
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s
t 2
0
1
9
:
2
7
5
1
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2759
2758
5.
CO
NCLU
SI
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clu
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t
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Sin
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ab
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ith
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m
a
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el
f
in
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E
G
s
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s
.
Mo
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m
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T
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also
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w
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ith
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C
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n
o
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ar
io
u
s
d
is
o
r
d
er
s
.
RE
F
E
R
E
NC
E
S
[1
]
A
.
Ba
h
ra
m
in
a
s
a
b
,
e
t
a
l.
,
“
Dire
c
ti
o
n
o
f
Co
u
p
li
n
g
f
ro
m
P
h
a
se
s o
f
In
tera
c
ti
n
g
Os
c
il
lato
rs:
A
P
e
rm
u
tatio
n
In
f
o
rm
a
ti
o
n
A
p
p
ro
a
c
h
,
”
Ph
y
sic
a
l
Rev
iew L
e
tt
e
rs
,
v
o
l.
1
0
0
,
2
0
0
8
.
[2
]
A
.
G
ro
th
,
“
Visu
a
li
z
a
ti
o
n
o
f
c
o
u
p
l
in
g
in
t
im
e
se
rie
s b
y
o
rd
e
r
re
c
u
rre
n
c
e
p
lo
ts
,
”
Ph
y
sic
a
l
Rev
iew
,
v
o
l.
7
2
,
2
0
0
5
.
[3
]
A
.
P
ik
o
v
sk
y
,
e
t
a
l.
,
“
S
y
n
c
h
ro
n
iza
ti
o
n
-
A
Un
iv
e
rsa
l
Co
n
c
e
p
t
in
No
n
li
n
e
a
r
S
c
ie
n
c
e
s,”
Ca
m
b
rid
g
e
Un
iv
e
rsit
y
P
re
ss
,
Ca
m
b
rid
g
e
,
En
g
lan
d
,
2
0
0
1
.
[4
]
A
.
S
tefa
n
o
v
sk
a
,
e
t
a
l.
,
“
Re
v
e
rsib
le
T
ra
n
siti
o
n
s
b
e
tw
e
e
n
S
y
n
c
h
ro
n
iza
ti
o
n
S
tate
s
o
f
th
e
Ca
rd
i
o
re
sp
ir
a
to
ry
s
y
ste
m
.
”
Ph
y
s R
e
v
L
e
tt
.
No
v
2
7
;
8
5
(
2
2
)
:4
8
3
1
-
4
,
2
0
0
0
.
[5
]
S
a
c
re
d
He
a
rt
He
a
lt
h
Ca
re
S
y
st
e
m
,
“
Am
b
u
lato
r
y
El
e
c
tro
e
n
c
e
p
h
a
lo
g
ra
p
h
y
(EE
G
)
Ca
rd
io
re
sp
irato
ry
S
y
ste
m
”
Ph
y
s.
Rev
.
L
e
tt
.
,
v
o
l
.
8
5
,
p
p
.
4
8
3
1
,
2
0
0
0
.
[6
]
M
.
Nik
n
a
z
a
r,
e
t
a
l.
,
“
A
Ne
w
F
ra
m
e
w
o
rk
Ba
se
d
o
n
Re
c
u
rre
n
c
e
Qu
a
n
ti
f
ica
ti
o
n
A
n
a
l
y
sis
f
o
r
Ep
il
e
p
ti
c
S
e
izu
re
De
tec
ti
o
n
,
”
IEE
E
J
o
u
rn
a
l
o
f
B
io
me
d
ica
l
a
n
d
He
a
lt
h
In
f
o
rm
a
ti
c
s,
v
o
l/
issu
e
:
1
7
(3
),
2
0
1
3
.
[7
]
J.
En
g
e
l,
e
t
a
l.
,
“
E
p
il
e
p
sy
:
A
Co
m
p
re
h
e
n
siv
e
T
e
x
tb
o
o
k
,
”
L
ip
p
in
c
o
t
t
W
il
li
a
m
s &
W
il
k
in
s,
2
0
0
7
.
[8
]
B.
L
it
t,
e
t
a
l.
,
“
T
ra
n
sla
ti
n
g
S
e
izu
re
De
tec
ti
o
n
,
P
re
d
ictio
n
a
n
d
B
ra
in
S
ti
m
u
latio
n
I
n
to
Im
p
lan
tab
l
e
De
v
ic
e
s
f
o
r
Ep
il
e
p
sy
,
”
in
Co
n
fer
e
n
c
e
Pro
c
e
e
d
in
g
s
in
th
e
1
st
I
n
ter
n
a
ti
o
n
a
l
IE
EE
EM
BS
C
o
n
fer
e
n
c
e
o
n
Ne
u
r
a
l
En
g
in
e
e
rin
g
,
p
p
.
4
8
5
–
4
8
8
,
2
0
0
3
.
[9
]
B.
L
it
t
a
n
d
K.
L
e
h
n
e
rtz,
“
S
e
izu
re
P
re
d
icti
o
n
a
n
d
th
e
P
re
se
izu
re
P
e
rio
d
,
”
Cu
rr
e
n
t
O
p
in
i
o
n
in
Ne
u
ro
l
o
g
y
,
v
o
l
/i
ss
u
e
:
1
5
(
2
),
p
p
.
1
7
3
–
1
7
7
,
2
0
0
2
.
[1
0
]
S
.
S
a
n
e
i
a
n
d
J.
Ch
a
m
b
e
rs,
“
EE
G
S
ig
n
a
l
P
ro
c
e
ss
in
g
,
”
W
il
e
y
-
In
ters
c
ien
c
e
,
2
0
0
7
.
[1
1
]
B.
S
c
h
e
lt
e
r,
e
t
a
l.
,
“
Do
F
a
lse
P
r
e
d
ictio
n
s
o
f
S
e
izu
re
s
De
p
e
n
d
o
n
th
e
S
tate
o
f
V
ig
il
a
n
c
e
?
”
Ep
il
e
p
sia
,
v
o
l/
issu
e
:
4
7
(
1
2
),
p
p
.
2
0
5
8
-
2
0
7
0
,
2
0
0
6
.
[1
2
]
R.
S
c
h
u
y
ler,
e
t
a
l.
,
“
E
p
il
e
p
t
icSeiz
u
re
De
tec
ti
o
n
,
”
E
n
g
i
n
e
e
rin
g
i
n
M
e
d
icin
e
a
n
d
B
io
l
o
g
y
M
a
g
a
zin
e
,
IE
EE
,
v
o
l/
issu
e
:
2
6
(
2
),
p
p
.
7
4
–
8
1
,
2
0
0
7
.
[1
3
]
B.
S
h
n
e
k
e
r
a
n
d
N.
F
o
u
n
ta
i
n
,
“
Ep
i
lep
sy
,
”
Dis
e
a
se
-
a
-
M
o
n
th
,
v
o
l/
issu
e
:
4
9
(
7
),
p
p
.
4
2
6
–
4
7
8
,
2
0
0
3
.
[1
4
]
M
.
W
in
terh
a
ld
e
r,
e
t
a
l
.
,
“
T
h
e
se
izu
re
p
re
d
ictio
n
c
h
a
ra
c
teristic:
a
g
e
n
e
ra
l
f
ra
m
e
w
o
r
k
to
a
ss
e
ss
m
a
n
d
c
o
m
p
a
re
se
izu
re
p
re
d
ictio
n
m
e
th
o
d
s,”
E
p
il
e
p
sy
a
n
d
Beh
a
v
io
r
,
2
0
0
3
.
[1
5
]
M
.
H.
D.
M
o
h
a
m
m
a
d
i,
“
I
m
p
ro
v
e
d
De
n
o
isin
g
M
e
th
o
d
f
o
r
Ultras
o
n
ic
Ech
o
w
it
h
M
o
th
e
r
W
a
v
e
let
Op
ti
m
iza
ti
o
n
a
n
d
b
e
st
b
a
sis
se
lec
ti
o
n
,
”
In
ter
n
a
ti
o
n
a
l
J
o
u
r
n
a
l
o
f
El
e
c
trica
l
a
n
d
C
o
mp
u
ter
En
g
in
e
e
rin
g
(
IJ
ECE
)
,
v
o
l/
issu
e
:
6
(
6
),
2
0
1
6
.
[1
6
]
N.
M
o
h
a
n
,
“
M
o
d
if
ied
V
a
riati
o
n
a
l
M
o
d
e
De
c
o
m
p
o
siti
o
n
f
o
r
P
o
w
e
r
L
in
e
In
ter
f
e
re
n
c
e
R
e
m
o
v
a
l
in
ECG
S
ig
n
a
ls
,”
In
ter
n
a
t
io
n
a
l
J
o
u
rn
a
l
o
f
E
lec
trica
l
a
n
d
C
o
mp
u
ter
En
g
in
e
e
rin
g
(
IJ
ECE
)
,
v
o
l/
issu
e
:
6
(1
)
,
2
0
1
6
.
[1
7
]
M
o
h
d
S
u
h
a
ib
Ki
d
w
a
i,
“
A
Re
v
ie
w
o
f
th
e
Re
c
u
rre
n
c
e
Ba
s
e
d
T
e
c
h
n
i
q
u
e
s
f
o
r
De
tec
ti
o
n
o
f
V
a
rio
u
s
Ne
u
ro
lo
g
ica
l
Diso
rd
e
rs
,
”
IJ
AR
CCE
,
Vo
l
5
Iss
u
e
9
,
2
0
1
6
.
[1
8
]
M
o
h
d
S
u
h
a
ib
Kid
w
a
i,
“
A
No
v
e
l
A
p
p
ro
a
c
h
to
S
tu
d
y
th
e
E
ff
e
c
ts
o
f
A
n
e
sth
e
sia
o
n
Re
sp
irato
r
y
S
ig
n
a
l
s
b
y
u
sin
g
th
e
EE
G
S
ig
n
a
ls”
,
In
ter
n
a
ti
o
n
a
l
J
o
u
r
n
a
l
o
f
E
lec
trica
l
a
n
d
Co
mp
u
ter
E
n
g
i
n
e
e
rin
g
(
IJ
ECE
)
,
V
o
l
7
Iss
u
e
6
,
2
0
1
7
.
[1
9
]
M
o
h
d
S
u
h
a
i
b
Kid
w
a
i,
“
Us
e
Of
R
e
c
u
rre
n
c
e
F
o
r
De
tec
ti
o
n
o
f
Ep
il
e
p
s
y
,
”
IJ
AIE
M
,
V
o
l
2
,
Iss
u
e
5
,
2
0
1
3
[2
0
]
M
o
h
d
S
u
h
a
i
b
Kid
w
a
i,
”
A
n
Eff
ic
ien
t
A
lg
o
rit
h
m
f
o
r
th
e
Dia
g
n
o
si
s
of
A
lzh
e
i
m
e
r
Dise
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se
by
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g
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ATLA
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”,
IJ
ET
T
CS
,
Vo
l
3
Iss
u
e
2
,
2
0
1
4
.
[2
1
]
M
.
T
h
iel,
M
.
C
.
R
o
m
a
n
o
,
J.
K
u
rt
h
s,
R.
M
e
u
c
c
i,
E.
A
ll
a
ria,
T
.
A
re
c
c
h
i,
“
In
f
lu
e
n
c
e
o
f
o
b
se
rv
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ti
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n
a
l
n
o
ise
o
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re
c
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rre
n
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q
u
a
n
ti
f
ica
ti
o
n
a
n
a
ly
sis
,
”
Ph
y
sic
a
D
1
7
1
(3
),
1
3
8
,
2
0
0
2
.
[2
2
]
M
.
T
h
iel,
M
.
C.
Ro
m
a
n
o
a
n
d
J.
Ku
rth
s,
“
A
n
a
l
y
ti
c
a
l
De
s
c
rip
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lo
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r Dy
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mic
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1
1
(
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0
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0
0
3
.
[2
3
]
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.
T
h
iel,
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.
C.
Ro
m
a
n
o
,
P
.
Re
a
d
,
a
n
d
J.
Ku
rth
s
,
“
S
u
rro
g
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te
b
a
se
d
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y
p
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sis T
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t
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tes
,
”
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o
s
14
(2
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2
3
4
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2
0
0
4
.
[2
4
]
N.
F
.
Ru
lk
o
v
,
M
.
M
.
S
u
sh
c
h
ik
,
L
.
S
.
T
si
m
rin
g
,
a
n
d
H.
D.
I.
A
b
a
rb
a
n
e
l,
“
Ge
n
e
ra
li
z
e
d
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y
n
c
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ro
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iza
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n
o
f
Ch
a
o
s
in
Dire
c
ti
o
n
a
ll
y
Co
u
p
led
Ch
a
o
t
ic S
y
ste
m
,
”
Ph
y
s.
Rev
.
E
5
1
,
9
8
0
,
1
9
9
5
.
[2
5
]
P
.
F
a
u
re
,
H.
Ko
rn
,
“
A
n
e
w
m
e
th
o
d
t
o
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stim
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te
th
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lm
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g
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v
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p
y
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ro
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r
e
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lo
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it
s
a
p
p
li
c
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ti
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e
u
ro
n
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l
sig
n
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ls,
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sic
a
D
1
2
2
,
2
6
5
,
1
9
9
8
.
[2
6
]
P
.
G
ra
s
sb
e
rg
e
r
a
n
d
I.
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r
o
c
a
c
c
ia,
“
Esti
m
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ti
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f
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lm
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g
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v
e
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tro
p
y
f
ro
m
a
c
h
a
o
ti
c
sig
n
a
l
,
”
Ph
y
s.
Rev
.
A
2
8
,
2
5
9
1
,
1
9
8
3
.
[2
7
]
P
.
T
a
ss
,
M
.
G
.
Ro
se
n
b
lu
m
,
J.
W
e
u
le,
J.
Ku
rth
s,
A
.
P
ik
o
v
sk
y
,
J.
V
o
lk
m
a
n
n
,
A
.
S
c
h
n
it
z
ler,
a
n
d
H.J.F
re
u
n
d
,
“
De
tec
ti
o
n
o
f
n
:
m
P
h
a
se
L
o
c
k
in
g
f
ro
m
No
is
y
Da
ta:
A
p
p
li
c
a
ti
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n
to
M
a
g
n
e
to
e
n
c
e
p
h
a
l
o
g
ra
p
h
y
,
”
P
h
y
s.
Rev
.
L
e
tt
.
V
o
l
.
8
1
,
N
o
.
1
5
,
1
9
9
8
.
Evaluation Warning : The document was created with Spire.PDF for Python.
I
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t J
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(
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2759
[2
8
]
R.
Qu
ian
Qu
iro
g
a
,
J.
A
rn
h
o
ld
a
n
d
P
.
G
ra
ss
b
e
r
g
e
r,
“
Lea
rn
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g
d
riv
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r
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re
sp
o
n
se
re
latio
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sh
i
p
s
f
ro
m
s
y
n
c
h
ro
n
iza
ti
o
n
p
a
tt
e
rn
s
,
”
Ph
y
s.
Rev
.
E
6
1
,
5
1
4
2
,
2
0
0
0
.
[2
9
]
S
.
J.
S
c
h
if
f
,
P
.
S
o
,
T
.
Ch
a
n
g
,
R.
E.
Bu
rk
e
,
a
n
d
T
.
S
a
u
e
r,
“
D
e
tec
ti
n
g
d
y
n
a
m
i
c
a
l
in
terd
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p
e
n
d
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n
d
g
e
n
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ra
li
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d
s
y
n
c
h
ro
n
y
th
ro
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g
h
m
u
tu
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l
p
re
d
ictio
n
in
a
n
e
u
ra
l
e
n
se
m
b
le
,
”
Ph
y
s.
Rev
.
E
5
4
,
6
7
0
8
,
1
9
9
6
.
[3
0
]
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.
S
c
h
re
ib
e
r,
“
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e
a
su
rin
g
In
f
o
rm
a
ti
o
n
T
ra
n
sf
e
r
,
”
Ph
y
s.
Rev
.
L
e
tt
.
8
5
,
4
6
,
2
0
0
0
.
B
I
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RAP
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th
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.
Evaluation Warning : The document was created with Spire.PDF for Python.