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1.
I
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[1
].
C
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[
2
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.
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[
4
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.
T
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I
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IJ
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[
5
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.
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R
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ai
d
s
b
as
ed
l
o
cal
w
i
s
d
o
m
w
as
ad
ap
t
ed
t
h
e
A
D
D
I
E
(
A
na
l
ys
i
s
,
D
e
s
i
gn,
D
e
ve
l
o
p
m
e
nt
,
I
m
p
l
e
m
e
n
t
a
t
i
o
n
a
nd
E
va
l
ua
t
i
o
n
)
m
ode
l
w
h
ic
h
is
th
e
t
he
m
o
s
t
o
f
t
he
c
ur
r
e
nt
i
ns
t
r
uc
t
i
o
na
l
d
e
s
i
g
n
m
o
d
e
l
[7
]
.
T
he
p
ha
s
e
of
de
v
e
l
opm
e
nt
c
he
m
i
s
t
r
y
t
each
i
n
g
ai
d
s
b
as
ed
l
o
cal
w
i
s
d
o
m
w
as
d
es
cr
i
b
ed
i
n f
i
ve
p
ha
s
e
:
a.
A
na
l
ys
i
s
p
ha
s
e
Co
n
s
i
s
t
s
o
f
(
1
)
an
al
y
s
i
s
an
d
d
et
er
m
i
n
e t
h
e p
r
o
d
u
ct
d
ev
e
l
o
p
m
e
n
t
o
b
j
ect
i
v
es
,
(2
)
an
al
y
ze t
h
e
l
ear
n
i
n
g
m
a
te
r
ia
l
s
a
n
d
co
l
l
ect
t
h
e r
ef
er
en
ces
,
(
3
)
c
o
nd
uc
t
a
n a
na
l
ys
i
s
t
o
w
a
r
d
s
t
he
p
r
o
d
uc
t
us
a
ge
’
s
t
a
r
ge
t
w
h
i
c
h
w
i
l
l
be
de
v
e
l
ope
d.
b.
D
e
si
g
n
p
ha
s
e
Co
n
s
i
s
t
s
o
f
(
1
)
c
r
eat
e a
d
es
i
g
n
o
f
t
each
i
n
g
ai
d
w
h
i
c
h
w
i
l
l
b
e d
ev
el
o
p
ed
,
an
d
(
2
)
cr
eat
e a
n
in
s
tr
u
m
e
n
t f
o
r
t
each
i
n
g
ai
d
s
a
s
se
s
s
m
e
n
t
.
s
c.
D
e
ve
l
o
p
m
e
nt
p
ha
s
e
C
on
s
i
s
t
of
(
1)
c
r
eat
e a
c
h
e
mi
s
t
r
y
t
e
a
c
hi
ng
a
i
d
s
,
w
hi
c
h a
r
e
cl
ay
m
ol
y
m
od,
e
le
c
tr
o
l
y
te
t
es
t
er
an
d
e
le
c
tr
o
p
la
tin
g
t
ool
s
,
(2
)
cr
eat
e a g
u
i
d
e b
o
o
k
,
(3
)
c
o
nd
uc
t
p
r
o
d
u
ct
r
ev
i
e
w
s
b
y
m
ed
i
a ex
p
er
t
s
,
m
a
t
er
i
a
l
ex
p
er
t
s
,
a
nd
r
ev
i
e
w
er
s
.
d.
I
m
p
le
m
e
n
ta
tio
n
p
ha
s
e
T
he
c
he
m
i
s
t
r
y
t
e
a
c
hi
n
g
a
i
d
s
w
a
s
us
e
d
i
n
c
h
e
m
is
tr
y
t
e
a
c
hi
ng
a
nd
l
e
a
r
ni
ng
f
o
r
s
t
ud
e
nt
s
gr
a
d
e
X
S
e
ni
o
r
H
i
gh
S
c
h
ool
.
e.
E
v
a
lu
a
tio
n
p
ha
s
e
E
v
al
u
a
t
e t
h
e l
ear
n
er
s
'
r
es
p
o
n
s
e
t
o
w
ar
d
s
t
h
e
ch
e
m
i
s
t
r
y
t
eac
h
i
n
g
ai
d
s
as
a
l
ear
n
i
n
g
m
ed
i
a.
T
h
e r
es
p
o
n
s
e
g
ai
n
ed
b
y
q
u
es
t
i
o
n
n
a
i
r
es
w
h
i
ch
co
n
s
i
s
t
s
o
f
8
a
s
p
ect
s
.
T
h
e
as
p
ect
s
w
er
e l
ear
n
i
n
g
co
n
f
o
r
m
i
t
y
,
m
at
er
i
al
c
o
n
f
o
r
m
i
t
y
,
p
r
a
c
tic
a
li
t
y
a
n
d
f
l
e
x
ib
ilit
y
,
ti
m
e
e
f
f
ic
i
e
n
c
y
,
to
o
l d
u
r
a
b
ilit
y
,
s
a
f
e
t
y
f
o
r
t
h
e
s
t
ud
e
nt
s,
a
e
s
t
h
e
t
i
c
s
a
nd
ki
t
b
o
x.
3.
R
ES
U
LT
S
A
ND AN
AL
Y
S
I
S
3.
1.
C
l
ay M
ol
ym
od
M
o
l
y
m
o
d
(
m
o
l
ec
u
l
ar
m
o
d
el
)
i
s
a t
h
r
ee
-
d
i
m
e
n
s
io
n
a
l m
o
d
e
l w
h
ic
h
d
e
f
i
n
e
s
a
m
o
le
c
u
la
r
s
tr
u
c
tu
r
e
[8
].
V
i
s
u
a
l
r
ep
r
es
en
t
at
i
o
n
s
a
n
d
p
h
y
s
i
cal
m
o
d
el
s
ar
e
co
m
m
o
n
p
l
ace i
n
c
h
e
m
i
s
t
r
y
t
each
i
n
g
a
n
d
l
ear
n
i
n
g
[9
].
O
n
e
o
f
t
h
ei
r
ap
p
l
i
cat
i
o
n
s
i
s
t
o
en
h
a
n
ce
t
h
e
s
p
at
i
al
a
w
ar
en
e
s
s
o
f
c
o
n
cep
t
s
i
n
c
h
e
m
i
s
t
r
y
t
each
i
n
g
an
d
l
ear
n
i
n
g
[1
0
].
O
n
e
c
o
m
po
n
e
n
t
of
m
ol
ym
od
w
h
i
c
h
i
s
t
h
e at
o
m
m
ad
e o
f
c
l
a
y
.
C
l
a
y
i
s
u
s
ed
a
s
t
h
e b
as
i
c
m
at
er
i
al
f
o
r
m
ak
e
t
h
e
p
o
tte
r
y
.
T
h
is
p
o
tte
r
y
i
n
d
u
s
tr
y
is
a
k
i
n
d
o
f
lo
c
a
l
w
is
d
o
m
in
K
a
s
o
n
g
a
n
,
Y
o
g
y
a
k
a
r
ta
[
11]
.
M
ol
y
m
od pr
ops
c
a
n
b
e s
een
i
n
F
i
g
u
r
e 1
.
F
i
g
ur
e
1
.
C
l
a
y
M
ol
y
m
od
Evaluation Warning : The document was created with Spire.PDF for Python.
IJ
E
R
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SSN
:
2252
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297
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85.
83%
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a
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a
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a
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n
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t
o
f
ab
s
t
r
act
m
o
l
ecu
l
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s
t
r
u
ct
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r
e.
L
ear
n
i
n
g
i
n
c
h
e
m
is
tr
y
ab
o
u
t m
o
le
c
u
la
r
g
e
o
m
e
tr
y
u
s
in
g
m
ode
l
s
b
eco
m
e
s
eas
i
er
t
o
u
n
d
er
s
t
an
d
b
y
t
h
e s
t
u
d
en
t
s
an
d
i
t
ca
n
en
r
i
ch
es
t
h
e s
t
u
d
en
t
s
'
l
ear
n
i
n
g
ex
p
er
i
en
ces
[1
2
].
I
n
ad
d
i
t
i
o
n
,
t
h
e
m
o
l
y
m
o
d
s
p
h
e
r
es
ar
e
m
ad
e o
f
cl
a
y
,
w
h
i
l
e
t
h
e
co
n
n
ect
i
n
g
r
o
d
s
u
s
e
a co
at
ed
w
i
r
e
w
i
t
h
a
p
la
s
tic
h
o
s
e
s
o
t
h
at
i
t
i
s
s
a
f
e
w
h
e
n
i
t
u
s
es
b
y
t
h
e
s
t
u
d
e
n
t
s
.
T
h
e
s
p
h
er
es
ar
e p
ai
n
t
ed
i
n
d
i
f
f
er
en
t
co
l
o
r
s
acco
r
d
i
n
g
t
o
t
h
e t
y
p
e o
f
t
h
e
at
o
m
s
o
t
h
e
y
l
o
o
k
m
o
r
e at
t
r
act
i
v
e.
T
h
e u
s
e o
f
at
t
r
act
i
v
e
t
each
i
n
g
ai
d
s
ca
n
i
n
cr
eas
e at
t
e
n
t
i
o
n
,
an
d
s
t
u
d
en
t
s
f
o
c
u
s
m
o
r
e o
n
t
h
e l
ear
n
i
n
g
p
r
o
c
e
s
s
; it
m
a
k
e
s
t
h
e
w
il
l e
a
s
il
y
u
n
d
e
r
s
ta
n
d
t
h
e
m
at
er
i
al
co
n
cep
t
s
.
3.
2.
E
l
ect
ro
l
y
t
e T
es
t
er
E
le
c
tr
o
ly
te
te
s
te
r
i
s
a
to
o
l
w
h
i
c
h
h
e
lp
s
to
te
s
t
w
h
e
t
h
e
r
a
s
o
l
u
tio
n
c
a
n
c
o
n
d
u
c
t e
le
c
tr
ic
it
y
o
r
n
o
t.
T
h
e
s
o
lu
tio
n
s
c
a
n
b
e
te
s
te
d
u
s
in
g
a
n
e
le
c
tr
o
l
y
te
te
s
te
r
; o
n
e
o
f
w
hi
c
h
i
s
a
s
ol
ut
i
on us
e
d i
n t
h
e
pr
oc
e
s
s
o
f
e
le
c
tr
o
p
la
tin
g
.
T
h
e
s
ilv
e
r
h
a
n
d
ic
r
a
f
t
in
d
u
s
tr
y
i
n
K
o
ta
g
e
d
e
,
Y
o
g
y
a
k
a
r
ta
,
u
s
e
s
e
le
c
tr
o
l
y
te
s
o
lu
t
io
n
s
w
h
ic
h
co
n
t
ai
n
s
g
i
l
d
i
n
g
m
et
al
s
s
o
t
h
a
t
t
h
e el
ect
r
o
p
l
at
i
n
g
p
r
o
ces
s
can
b
e d
o
n
e
[
13
]
.
E
le
c
tr
o
ly
t
e t
e
s
t
er
can
b
e s
een
in
F
i
g
ur
e
2
.
F
i
g
ur
e
2
.
E
le
c
tr
o
ly
te
T
e
s
te
r
O
v
e
r
a
ll,
b
as
ed
o
n
r
ev
i
e
w
er
as
s
es
m
en
t
,
t
h
e
e
l
e
c
t
r
ol
y
t
e
t
e
s
t
e
r
h
a
s
v
e
r
y
g
ood qu
a
l
i
t
y
w
i
t
h
85.
17%
of
i
d
eal
p
er
cen
t
ag
e.
T
h
e ef
f
i
ci
e
n
c
y
u
s
ag
e
o
f
t
h
e t
o
o
l
i
s
n
eces
s
ar
y
f
o
r
s
m
o
o
t
h
a
n
d
s
u
cces
s
f
u
l
l
ear
n
i
n
g
act
i
v
i
t
i
e
s
b
ecau
s
e i
t
w
i
l
l
s
a
v
e t
h
e p
r
act
i
ce t
i
m
e.
E
l
ect
r
o
l
y
t
e t
es
t
er
i
s
v
er
y
e
f
f
i
ci
e
n
t
w
h
e
n
i
t
u
s
ed
,
b
ecau
s
e t
h
e t
o
o
l
i
s
eas
y
t
o u
s
e
a
n
d doe
s
n
ot
r
e
qu
i
r
e
a
l
on
g
t
i
m
e
t
o
m
a
k
e
t
h
is
to
o
ls
.
3.
3.
E
l
e
c
t
r
op
l
at
i
n
g T
ool
E
le
c
tr
o
p
la
tin
g
to
o
l
s
h
o
w
s
a
s
i
m
p
le
e
le
c
tr
o
p
la
tin
g
p
r
o
c
e
s
s
i
n
K
o
ta
g
e
d
e
,
in
s
il
v
e
r
h
a
n
d
ic
r
a
f
t in
d
u
s
tr
y
.
T
h
e p
r
i
n
ci
p
l
e o
f
el
ect
r
o
p
l
at
i
n
g
i
s
t
h
at
t
h
e co
at
ed
m
et
al
t
r
ea
t
ed
as
a cat
h
o
d
e
w
h
i
ch
co
n
n
e
ct
ed
w
i
t
h
a n
e
g
at
i
v
e
p
o
l
e an
d
t
h
e co
at
i
n
g
m
et
al
t
r
e
at
ed
as
an
o
d
e
w
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[
1]
E
.
v
a
n R
os
s
um
an
d
R
.
H
am
er
,
“
T
he
m
e
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ni
ng
of
l
e
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s
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20
10
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2]
E
. O
t
o
r
,
e
t a
l.
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f
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111
-
1
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2
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.
[
3]
J
.
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22
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-
2
34,
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011
.
[
5]
T.
La
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l.
,
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-
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.
[
6]
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. A
b
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7]
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.
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8]
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[
9]
V
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e
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k
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:
25
(
1
0)
,
pp
.
122
7
-
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45,
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[
1
0]
C.
Co
p
o
l
o
a
nd
P
.
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ou
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l
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s
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l/is
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)
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2
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-
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5,
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[
1
1]
S
.
G
u
s
ta
m
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t a
l.
,
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p.
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-
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[
1
2]
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ar
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t
as
,
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s
e
ar
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d R
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:
10
(
20)
,
p
p.
2
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-
275
7,
20
15
.
[
1
3]
R.
P
u
t
ra
,
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t
a
l.
,
“
R
e
m
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v
a
l C
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nt
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o
nf
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s
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ar
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m
pl
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m
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on
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d
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on
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at
he
m
at
i
c
an
d
S
ci
en
ce
,
p
p.
83
-
88
,
2
01
6.
Evaluation Warning : The document was created with Spire.PDF for Python.