SLIC Superpixel Based Self Organizing Maps Algorithm for Segmentation of Microarray Images

Abstract

We can find the simultaneous monitoring of thousands of genes in parallel Microarray technology. As per these measurements, microarray technology have proven powerful in gene expression profiling for discovering new types of diseases and for predicting the type of a disease. Gridding, Intensity extraction, Enhancement and Segmentation are important steps in microarray image analysis. This paper gives simple linear iterative clustering (SLIC) based self organizing maps (SOM) algorithm for segmentation of microarray image. The clusters of pixels which share similar features are called Superpixels, thus they can be used as mid-level units to decrease the computational cost in many vision applications. The proposed algorithm utilizes superpixels as clustering objects instead of pixels. The qualitative and quantitative analysis shows that the proposed method produces better segmentation quality than k-means, fuzzy c-means and self organizing maps clustering methods.